Director, Global Value & Access Strategy (Cell and Gene Therapy)

Vertex Pharmaceuticals Inc (US); United States; Hybrid; USD 212,000 - 318,000; Full time

Job summary

Vertex Pharmaceuticals Inc. in the United States seeks a Director, T1D Market Access lead within the Global Value and Access Strategy (GVAS) portfolio to develop global market access strategies for early-stage T1D assets, align with regional access colleagues, and inform commercial plans.

The role requires 8+ years in biotech/pharma and strong US ex-US payer knowledge, with a focus on pricing, value evidence, and cross-functional leadership in a matrix environment.

Job description

Job Description Background and Job Description: Vertex operates at the forefront of scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Casgevy, a gene therapy for sickle cell disease and beta-thalassemia and Journavx, a novel new treatment for moderate to severe acute pain. Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in kidney diseases, Type 1 diabetes, among others. Vertex is investigating and advancing cell therapies aimed at treating an underlying cause of T1D — the absence of insulin-producing cells. For over 100 years, improvements in insulin and technologies for insulin management have helped people with T1D manage their condition. However, there are very few approved treatments that address a root cause of T1D — the absence of insulin-producing cells in the pancreatic islets. Our investigational approach is to replace the insulin-producing cells that have been destroyed in people with T1D. We’re evaluating multiple approaches to deliver our proprietary, fully-differentiated, insulin-producing cells. Market Access is a key commercial function that ensures transformative Vertex therapies are appropriately funded and ultimately make it into the hands of the patients around the world. GVAS works cross-functionally and across regions to ensure the payer view is represented in commercial and development plans across the lifecycle. We are driven by a desire to deliver groundbreaking pricing & reimbursement solutions to allow our medicines to reach patients faster than ever before. The Director, T1D will serve as a T1D Market Access Lead within our Cell and Gene Therapy (CGT) portfolio in the Global Value and Access Strategy (GVAS) team. The individual will be responsible for leading the development of Global Market Access strategies for early-stage pipeline assets in the T1D portfolio, ensuring enterprise planning to enable optimal patient access. In this capacity, the individual will help to inform development of T1D prioritization/portfolio strategy and ultimately the commercial strategy, to ensure price and access success. This individual will lead the assessment of price/access potential and key considerations such as indication/launch sequencing for these new indications in close collaboration with cross-functional and regional access colleagues. This role will also contribute to cross-portfolio capability building and thought leadership projects that advance knowledge of and readiness for the rapidly evolving Global payer environment. This position reports to the Senior Director, Cell and Gene Therapy within GVAS.

Key Responsibilities:

• Lead payer strategic planning to ensure value and access optimization for early-stage pipeline assets in the T1D portfolio
• Lead development and refinement of Market Access strategies and core Global P&R deliverables operating within the cross-functional, cross-regional commercialization process
• Accountable for Global Payer Plans, which integrate value evidence generation, strategic pricing, value communications, stakeholder engagement to support successful reimbursement and pricing
• Ensure the payer position is consistently represented to internal stakeholders and ensure robust strategic input into commercialization and development decisions
• Support strategies with deep functional knowledge, in-depth market research, environmental data & analogs
• Inform financial forecasts
• Partner with HEOR and Global Marketing to ensure robust value proposition and integrated evidence plans are optimized to support global market access and reimbursement
• Lead capability building and thought leadership projects that advance knowledge of and readiness for the rapidly evolving Global payer environment
• Maintain industry awareness and proactively address changes in market trends, competition, product acceptance and new product releases and adjust Market Access plans accordingly
• Collaborate closely with HEOR, International P&R, Corporate Affairs, US Managed Markets, Countries, Marketing and Clinical Development counterparts to ensure value and access optimization

Qualifications:

• 8+ years of direct biotechnology / pharmaceutical industry experience and/or payer experience
• Strong knowledge of both US and ex-US healthcare systems required, experience in comparable global and/or specialty disease area role considered a plus
• Demonstrated ability to think strategically and make sound pricing and market access recommendations
• Entrepreneurial, energetic, dynamic, enthusiastic, decisive, and self-motivated; possesses a sense of urgency with the ability and strong desire to "make things happen"
• Strong practical, quantitative and analytical skills combined with a sound understanding of how to successfully apply pricing & reimbursement / HEOR principles
• General experience in commercialization and drug development
• Cell and Gene Therapy experience preferred
• Demonstrated ability to effectively operate within highly cross-functional teams within a matrix environment
• Exhibits outstanding written and oral communication skills, including the ability to effectively write and deliver presentations to professionals at all levels within Vertex
• Demonstrated relationship building at all levels of the organization and across geographies
• Recognized as a team player with excellent interpersonal skills who is flexible and reliable
• Displays sound ethics and a fit for Vertex’s core values

Education:

BA/BS in field of study requiring quantitative analysis; advanced degree preferred

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$212,000 - $318,000

Disclosure Statement:

This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager.

Help Us Achieve Our Mission

Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases and conditions. The company has approved therapies for cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia, acute pain and acromegaly, and it continues to advance clinical and research programs in these areas. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including IgA nephropathy, neuropathic pain, APOL1-mediated kidney disease, primary membranous nephropathy, congenital adrenal hyperplasia, ACTH-dependent Cushing's syndrome, autosomal dominant polycystic kidney disease, type 1 diabetes, generalized myasthenia gravis, and myotonic dystrophy type 1.

Vertex was founded in 1989 and has its global headquarters in Boston, with international headquarters in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East.

Vertex is consistently recognized as one of the industry's top places to work, including 16 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For.

For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on LinkedIn, Facebook, Instagram, YouTube, and X.

We believe our culture is one of Vertex’s greatest strengths and a key enabler of our ability to deliver transformative medicines for patients who need them. Rooted in innovation, purpose and collaboration, our culture empowers people to take smart risks, challenge conventional thinking and do their best work. The diversity of our people is central to that culture. By bringing together individuals with different backgrounds, experiences and perspectives, we foster an environment where new ideas thrive, better decisions are made and breakthrough innovation is possible. We are committed to creating a workplace where everyone feels valued, included and connected to our shared mission, because we know that our unique culture and the collective strength of our people are what set Vertex apart.