Director, Evidence Generation

Kiniksa Pharmaceuticals; Lexington (VA); On-site; USD 191,000 - 264,000; Full time

Job summary

Kiniksa Pharmaceuticals is looking for an experienced Associate Director of Evidence Generation to join our Lexington, VA team onsite five days a week. You will lead evidence-generation plans in collaboration with Global Medical Affairs and cross-functional teams, overseeing CRO activities, translating outputs into clear, accurate messaging, and presenting findings to diverse audiences.

The role requires a strong track record in data-driven clinical research, excellent communication, and the

Qualifications

• Ten+ years of experience in evidence generation or closely related fields.
• PhD/PharmD/MD or advanced science degree (MS/MPH) accepted.
• Direct experience leading disease registries in pharma or CRO, preferably rare diseases.
• Excellent attention to detail and data-driven mindset.
• Strong communication, collaboration, and problem-solving skills.
• Robust analytical skills with clinical data interpretation experience.
• Independent, fast-paced, compliant, and results-driven.
• Willingness to travel as required.

Responsibilities

• Identify evidence gaps by engaging stakeholders and defining clinical questions.
• Plan, design, and execute evidence-generation initiatives and protocols.
• Manage timelines, deliverables, and budgets for projects.
• Oversee CRO-led activities and data collection.
• Translate findings into clear, compliant messaging for stakeholders.
• Present data to diverse internal and external audiences.
• Collaborate to ensure alignment with corporate and product needs.
• Identify process improvements and leverage AI tools.

Skills

Evidence generation

Data presentation

Scientific communication

Cross-functional collaboration

Project management

Education

PhD/PharmD/MD or MS/MPH

Tools

Microsoft Word

Microsoft Excel

PowerPoint

CoPilot

Outlook

AI tools

Job description

Kiniksa Pharmaceuticals is a commercial‑stage biopharmaceutical company developing and commercializing novel therapies for diseases with unmet need, with a focus on cardiovascular indications. With deep expertise in immunology and inflammation, Kiniksa is advancing a growing portfolio of approved and investigational medicines, anchored by its lead product, ARCALYST®, the first and only FDA‑approved therapy for recurrent pericarditis. Grounded in rigorous science and bold innovation, the company fosters a highly collaborative, patient‑first culture led by accomplished life sciences leaders. At Kiniksa, talented individuals are trusted and empowered to make a real impact—shaping the future of medicine while improving the lives of patients who need it most.

Reporting to the Medical Director, Global Medical Affairs, the Associate Director of Evidence Generation will develop and execute evidence-generation plans, ensuring close alignment with product strategy. In close collaboration with Global Medical Affairs and cross-functional team members, this role will be responsible for driving the execution of a variety of evidence generation activities such as studies on natural history of disease, treatment trends, claims data, qualitative/quantitative research, and registries.

This role is based in the Lexington office and requires employees to be onsite five days a week.

Responsibilities (including, but not limited to):

• Engage with both internal and external stakeholders to perform evidence gap analyses that systematically and proactively identify key unanswered clinical and scientific questions
• Support the planning, design, and execution of evidence generation initiatives including conceptualization, document preparation, protocol reviews, and operational plans
• Manage timelines, deliverables, and budgets for all evidence generation initiatives
• Provide oversight of all evidence generation activity, including CRO-led activities (e.g., site trainings, data collection, data management)
• Translate evidence generation outputs into clear, concise, and targeted messaging and while maintaining medical accuracy and compliance
• Confidently present data to broad range of audiences, both in internal and external settings
• Drive appropriate collaboration with both internal and external stakeholders to assure evidence generation initiatives fit both corporate and product needs
• Closely collaborate with Scientific Communications to assure proper accurate, timely, and impactful dissemination of emerging evidence
• Proactively identify opportunities to improve evidence generation processes and efficiencies, including use of innovative tools and AI

Standout Skills for Success:

• Proactively identify opportunities for evidence generation
• Will clearly communicate complex data sets to various stakeholders
• Will review all datasets and final deliverables, assuring they are thorough, precise, and accurate
• Owns accuracy and timeliness of all deliverables

Qualifications:

• 10+ years of experience in related fields with a concentration in evidence generation
• Scientific degree (PhD, PharmD, MD) or relevant advanced science degree (MS, MPH)
• Direct experience in a pharmaceutical or CRO leading the planning and execution of a disease registry, preferably within rare disease space
• Strong attention to detail
• Ability to collaborate effectively with internal stakeholders and external stakeholders
• Excellent verbal and written communication skills, presentation skills, conflict management, and problem-solving skills are required
• Strong analytical skills and experience with clinical data presentation and interpretation
• Efficient independent worker with ability to focus and drive for results
• Ability to work in a fast paced-environment and to handle multiple tasksStrong commitment to compliance and ethical standards
• High proficiency in Microsoft Word, Excel, PowerPoint, CoPilot, and Outlook
• Experience with AI preferred
• Some travel may be required

Compensation decisions are based on objective criteria including role responsibilities, experience/qualifications, internal equity, geographic location, and external market benchmarks.

Pay Range

$191,000—$264,000 USD

Kiniksa is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, transgender status, age, genetics, national origin, protected veteran status, or disability status, or any other legally protected category. We will ensure that individuals with disabilities areprovidedreasonable accommodation toparticipatein the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Kiniksa does not accept unsolicited resumes from staffing agencies or search firms. Any resumes submitted without a signed agreement will be considered property of Kiniksa, and no fees will be paid.