Director, Disease Area Strategy Lead – General Medicine

Amgen; Thousand Oaks (CA); On-site; USD 196,000 - 265,000; Full time

Job summary

Amgen seeks a Director, Disease Area Strategy Lead to shape the General Medicine portfolio strategy across cardiovascular disease and bone health. You will integrate scientific, clinical, patient, competitive and commercial insights to define asset priorities and guide early development, with cross‑functional leadership across R&D, Medical, Commercial and BD.

In this role you will lead commercial assessments for early programs, develop target product profiles, forecast needs, and influence

Qualifications

• Doctorate or Master’s degree with marketing/commercial experience in biotech/pharma.
• Experience shaping disease-area strategy and portfolio planning.
• Strong ability to lead cross-functional teams and influence decisions.

Responsibilities

• Lead ongoing development and evolution of General Medicine TA strategy with cross-functional partners.
• Serve as Commercial lead for early pipeline projects, informing investment and development decisions.
• Develop target product profiles, forecast market opportunities and support portfolio prioritization.

Skills

Cross-functional leadership

Strategic thinking

Commercial acumen

Forecasting

Portfolio strategy

Education

Doctorate degree

Master’s degree

Bachelor’s degree

Job description

Career Category Marketing Job Description

Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity‑related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives. Our award‑winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Director, Disease Area Strategy Lead

What you will do

Let’s do this. Let’s change the world. As Amgen continues to invest in discovery research and early pipeline development, the Disease Area Strategy Lead (DASL) function plays a critical role in shaping where we invest and how scientific innovation is translated into differentiated medicines with meaningful value for patients. The Director, Disease Area Strategy Lead – General Medicine will help shape the future of Amgen’s General Medicine portfolio by integrating scientific, clinical, patient, competitive and commercial perspectives into therapeutic area, portfolio and early asset decisions. The role operates at the intersection of R&D, commercial, and therapeutic area strategy. Working closely with the Executive Director DASL and cross‑functional leaders, the Director will lead the ongoing development and evolution of the General Medicine therapeutic area strategy and translate strategic priorities into implications for disease areas, franchises, pipeline investments and individual programs. The Director will also serve as the Commercial strategic lead for early pipeline projects and programs from discovery through early development. Success in this role requires strong strategic judgment, scientific curiosity and commercial acumen, combined with the ability to build trusted cross‑functional partnerships and drive complex questions toward clear recommendations and decisions. In this role you will be responsible for the following:

• Therapeutic Area Strategy Lead the ongoing development and evolution of the General Medicine (Cardiovascular Disease and Bone Health) therapeutic area strategy, in partnership with the Executive Director DASL and cross‑functional leaders. Translate TA ambitions into disease and franchise priorities, portfolio implications, investment priorities and strategic actions. Maintain a forward‑looking view of evolving science, standards of care, patient and customer needs, competitive dynamics and Amgen’s portfolio, and assess implications for strategy. Assess where Amgen has a differentiated right to win, where opportunities warrant investment, and where we should remain selective or deprioritize investment. Ensure asset and program decisions remain connected to broader TA and franchise strategy, including explicit trade‑offs across assets, diseases, mechanisms and platforms. Partner with Business Development and Commercial BD to inform external innovation priorities and opportunity assessments in the context of The General Medicine TA and portfolio strategy.
• Early Pipeline & Program Commercial Leadership Serve as the Commercial strategic lead and representative for early pipeline projects and programs, developing and representing the Commercial point of view through program evolution and governance. Partner with Research, Development, Medical and other functions to define the patient population, unmet need, future treatment context, differentiation requirements, product profile and evidence needs for a compelling opportunity. Identify critical strategic and commercial questions early enough to influence research, development and investment choices. Assess whether scientific and technical success can translate into a differentiated and commercially attractive medicine, and develop recommendations regarding progression, investment, partnering or discontinuation. Lead cross‑functional team in the creation of target product profiles and development strategies that reflect patient needs, future standards of care and meaningful differentiation. Lead New Product Planning and early commercial assessments for assigned programs, including market and competitive assessment, patient segmentation, positioning, forecasting and commercial opportunity assessment to inform product and investment strategy. Drive cross‑functional opportunity assessments (e.g., forecast estimates, eNPVs, competitive landscapes) across development stages to inform indication prioritization, sequencing, and patient‑impact expansion opportunities.
• Cross‑Functional Leadership & Strategic Decision Support Partner across Research, Development, Medical, Competitive Intelligence, Business Analytics and Insights, Commercial and other functions to drive complex asset‑ and therapeutic area‑level strategic work, bringing together the right expertise, challenging assumptions, building alignment and moving critical questions toward decisions. Structure ambiguous strategic questions and identify the issues, assumptions and evidence most important to the decision. Integrate qualitative and quantitative evidence, including scientific and clinical data, customer and KOL insights, competitive intelligence, epidemiology, market research, RWE, forecasting and analytics. Develop clear recommendations despite uncertainty, communicate complex conclusions concisely, and influence effectively without formal authority to create clarity, alignment and momentum.

Win What we expect of you

We are all different, yet we all use our unique contributions to serve patients.

Basic Qualifications:

Doctorate degree and 4 years of marketing and/or commercial experience, OR Master’s degree and 7 years of marketing and/or commercial experience, OR Bachelor’s degree and 9 years of marketing and/or commercial experience.

Preferred Qualifications:

Advanced degree such as an MBA, PhD, PharmD, MD, MPH or other relevant scientific or business discipline preferred. Experience in the biopharmaceutical industry, life sciences strategy consulting or a related field, with demonstrated ability to solve complex strategic and commercial problems. Experience in New Product Planning, pipeline commercial strategy, portfolio strategy, commercial development, strategy consulting, forecasting, market research, analytics, business development or related disciplines, with ability to integrate across functions. Experience evaluating early‑stage assets, disease opportunities or product concepts, including patient need, future treatment landscapes, differentiation, positioning and commercial potential. Therapeutic area experience in cardiovascular disease, bone health, or other General Medicine areas preferred, with demonstrated ability to rapidly build expertise across new diseases and scientific areas. Strong scientific and clinical learning agility, with the ability to engage credibly with scientific and clinical experts and translate technical information into strategic implications. Strong qualitative and quantitative strategic judgment, including the ability to structure ambiguous problems, identify decision‑critical assumptions, evaluate trade‑offs and develop recommendations despite uncertainty. Demonstrated ability to lead through influence and build trusted cross‑functional partnerships, creating direction, alignment and momentum across Research, Development, Medical, Commercial and other functions.

Thrive

What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well‑being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

What you can expect of us

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales‑based incentive plan Stock‑based long‑term incentives Award‑winning time‑off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Sponsorship

Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Application Deadline

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Equal Opportunity Statement

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Salary Range

Salary Range 195,880.80USD -265,015.20 USD

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. For more information, visit www.amgen.com and follow us on www.twitter.com/amgen.