Director, Commercial Transformation

Vertex Pharmaceuticals LLC; Boston (MA); Hybrid; USD 214,000 - 320,000; Full time

Job summary

Vertex Pharmaceuticals LLC is seeking a Director, Commercial Transformation to lead initiatives that enhance Vertex's commercial capabilities, operating models, and processes. You will diagnose needs, develop business cases, secure budgets, and drive strategy with cross-functional teams to deliver measurable value for patients and the business.

In this hybrid/on-site role, you will partner with Finance and DTE to establish investment assumptions, monitor adoption, and guide leadership through

Qualifications

• Pharma/biotech commercial experience or related field preferred.
• Strong analytical skills to assess data and inform decisions.
• Experience building business cases and facilitating strategic analyses.

Responsibilities

• Serve as trusted advisor to senior commercial and enterprise leaders on transformation opportunities and priorities.
• Ensure transformation initiatives have a clear diagnosis, business case, and defined benefits realization plan.
• Lead transformation initiatives from start to finish, including securing budget and cross-functional connectivity.
• Cultivate partnerships with cross-functional teams to understand end-user impact and change capacity.
• Prepare governance materials and communicate progress to senior leadership.
• Respond proactively to market dynamics and scale internal capabilities.

Skills

Transformation leadership

Cross-functional influence

Strategic analysis

ROI / cost-benefit

Ambiguity navigation

Business case experience

Education

Bachelor's degree in a relevant field

Job description

Job Description

General Summary:

The Director, Commercial Transformation, is a key role within the Vertex Commercial Transformation Office, responsible for leading initiatives that will improve Vertex's commercial capabilities, operating models and processes. Reporting to the Transformation Office Lead, this role will execute complex transformation programs, proactively perform forward looking views of commercial capability builds, as well as reactive assessments of gaps/opportunities that require immediate remediation. The Director of Transformation will assess, diagnose, and recommend how transformation initiatives are resourced, executed, and deployed across the organization.

Key Duties and Responsibilities:

• Serve as a trusted advisor to senior commercial and enterprise leaders on transformation opportunities and priorities.
• Ensure transformation initiatives have clear diagnosis, business case and defined benefit-realization plan.
• Lead transformation initiatives from start to finish, including securing budget, developing connectivity cross functionally and delivering the work
• Cultivate strong partnerships with cross-functional teams to understand end user impact of transformation initiatives and organizational capacity for change.
• Prepare content for governance forums to drive effective and timely decision-making, and reading out to senior leadership on progress
• Proactively respond to the dynamics of a changing external marketplace and scaling internal organization.

Executing for Results

• A leader that sets clear and challenging goals for transformation initiatives, tenacious and accountable in driving results.
• Exceptional project manager with proven ability to successfully navigate a fast-paced environment, adapt nimbly, and take smart risks.
• A partner with DTE to leverage technology, advance AI adoption and meaningfully influence our ways of working/ways of successfully commercializing Vertex medicines.
• A parter with Finance to establish investment assumptions and validate benefits.

Leading Adoption

• Clear and engaging communicator; makes the transformation story accessible and relevant for different audiences.
• End-user oriented - tuned into how change will land and impact the organizations to help leaders respond constructively.
• A leader who drives the organization's performance with an attitude of continuous improvement by being open to feedback and differing ideas.
• Monitor adoption and business impact after implementation; ensure corrective actions are taken when outcomes do not meet expectations.

Knowledge and Skills:

• Pharma/biotech industry experience preferred with commercialization experience either in global, regional, or market specific roles.
• Comfortable working in ambiguity, taking initiative, and navigating sensitive topics with multiple stakeholders.
• Strong analytical skills to seek out and assess data to get to the core of an issue/opportunity.
• Experience building business cases or conducting strategic analyses to inform senior decision-making.
• A passion for technology and creative problem-solving to direct the development or adoption of new, innovating solutions.
• Strong financial acumen or experience partnering with Finance to develop ROI analysis, cost-benefit analysis, and value realization.
• Superior cross-functional collaboration and influencing skills and ability to inspire and motivate teams.

Education and Experience:

• Bachelor's degree in a relevant field
• Typically requires 10 years of relevant biotech/pharmaceutical commercial experience
• Experience with branded drug products, management consulting, corporate strategy, change management, or organizational transformation.

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$213,600 - $320,400

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [e-mail]