Director, Clinical Study Start-Up & Site Contracts

Summit Therapeutics, Inc.; United States; On-site; USD 203,000 - 253,000; Full time

Job summary

Summit Therapeutics Inc. is seeking an experienced Director to join our Clinical Operations team. This role manages site agreements for oncology programs, focusing on fair market value negotiations and timely site activations.

You will lead cross-functional collaboration with Legal, Finance, CROs and clinical teams to finalize budgets, contracts and related documentation, ensuring regulatory and company standards are met.

Qualifications

• Minimum 10+ years’ experience with clinical trial site agreements in biotech or pharma.
• Oncology experience is highly desirable.
• Strong global negotiation and contract management skills.
• Budgeting and financial acumen essential.
• Experience with global site budgets and escalation pathways.
• Knowledge of CTA risk and fallback language.
• Proficient with MS Office and document management tools.
• Clear, concise communication and collaboration across departments.

Responsibilities

• Lead development of pricing strategies for site budgets to enable contract execution and site activation.
• Negotiate and finalize site agreements, including budgets, contracts, and other necessary documentation.
• Rigorous analysis of budgets to secure best price and value.
• Present the budget to the Chief Accounting Officer for approval.
• Collaborate with Legal, Finance, CRO and clinical teams to ensure compliance.
• Maintain relationships with CROs, FSPs, and clinical sites.
• Provide study-wide site payment estimates and forecasts.
• Develop outsourcing strategies to support clinical trials across phases.

Skills

Global negotiation

Contract management

Budgeting & financial analysis

Cross-functional collaboration

Communication skills

GCP knowledge

Problem solving

Attention to detail

Education

Bachelor's degree in Life Sciences or related field

Tools

MS Office

Document management systems

Job description

Summit Therapeutics Inc. is seeking an experienced Director to join our Clinical Operations team. This role manages site agreements for oncology programs, focusing on fair market value negotiations and timely site activations.

You will lead cross-functional collaboration with Legal, Finance, CROs and clinical teams to finalize budgets, contracts and related documentation, ensuring regulatory and company standards are met.