Director, Clinical Sciences

Hemab Therapeutics; Cambridge (MA); Presencial; USD 200.000 - 260.000; Jornada completa

Descripción de la vacante

Hemab Therapeutics in Cambridge, MA, is seeking a Director, Clinical Sciences to turn scientific findings into well-designed clinical studies and clear evidence of how our therapies perform in patients. You will own protocol development, study execution and data interpretation, working closely with Medical Directors and colleagues across clinical development, regulatory and other functions.

In this leadership role you will shape study documents, guide sites and vendors, analyze study results and

Formación

• Substantial clinical science or clinical research experience in drug development with direct responsibility for clinical studies.
• Experience developing clinical protocols and interpreting safety and efficacy data from interventional studies.
• Strong working knowledge of ICH-GCP, clinical study design and drug development in a regulated environment.
• The scientific judgement to interpret clinical information and apply it to study decisions.
• Experience working effectively with investigators, vendors and cross-functional clinical, medical and regulatory colleagues.

Responsabilidades

• Lead the clinical science contribution to study strategy, design and execution, keeping patient needs at the centre of decisions.
• Drive protocol development with the Medical Director, including amendments as data or study needs require.
• Own the scientific review of clinical study data, identify discrepancies and translate data into actions for the team.
• Shape study documents and plans, including informed consent forms, eCRFs, MSPs and data review plans.
• Guide sites and vendors on protocol requirements and participant management for consistent execution.
• Partner across clinical development to analyse and interpret study results.
• Translate study findings for internal and external audiences alongside the Medical Director.
• Develop clinical content for regulatory documents (investigator brochures, safety reports, study reports, registrations).

Conocimientos

Clinical science experience

Clinical research in drug development

ICH-GCP knowledge

Clinical study design

Cross-functional collaboration

Educación

Advanced scientific or clinical degree

Descripción del empleo

Reporting to

VP, Clinical Sciences

About Hemab

Hemab is building preventative treatments for serious, underserved bleeding disorders. These are therapies designed to work with the body's own biology and stop bleeds before they start, instead of treating them after they happen. We're patient-first, science-led and clinical-stage - with a pipeline that takes different scientific approaches to different patient needs.

We went public via our 2026 IPO, and we're scaling across two homes: Cambridge, MA, USA, and Copenhagen, Denmark.

The role

As Director, Clinical Sciences, you'll help turn Hemab's science into well-designed clinical studies and clear evidence about how our treatments perform in patients. You'll take scientific ownership across protocol development, study execution and data interpretation, working closely with Medical Directors and colleagues across clinical development, regulatory and other functions.

What you'll do

• Lead the clinical science contribution to study strategy, design and execution, keeping the scientific questions and patient needs at the centre of decisions.
• Drive protocol development with the Medical Director, including amendments as emerging data or study needs require.
• Own the scientific review of clinical study data, identify discrepancies and trends, and turn emerging safety and efficacy data into clear questions and actions for the team.
• Shape study documents and plans, including informed consent forms, eCRFs, medical monitoring plans and data review plans.
• Guide sites and vendors on protocol requirements, eligibility criteria and participant management so studies are executed consistently and to the intended design.
• Partner across clinical development to analyse and interpret study results and build a clear understanding of what the data mean.
• Translate study findings for internal and external audiences alongside the Medical Director.
• Develop clinical content for regulatory documents, including investigator brochures, annual safety reports, clinical study reports and registration submissions.

What you'll bring to Hemab

• Substantial clinical science or clinical research experience in drug development, with direct responsibility for clinical studies.
• Experience developing clinical protocols and interpreting safety and efficacy data from interventional studies.
• A strong working knowledge of ICH-GCP, clinical study design and drug development in a regulated environment.
• The scientific judgement to interpret clinical information, literature and changing treatment approaches and apply it to study and development decisions.
• Experience working effectively with investigators, vendors and cross-functional clinical, medical and regulatory colleagues.

Nice to have

• Experience in haematology, rare disease or bleeding disorders.
• Experience contributing to development programmes through later-stage studies and registration.
• An advanced scientific or clinical degree.

What to expect, honestly

Hemab is still building a lot of its own structure. Systems here tend to get created as we need them, not handed down in advance. Whoever takes this role will likely build some of their own process instead of inheriting a finished one. We work across two hubs and multiple time zones - bridging that well takes real, deliberate effort. And because we're growing quickly, priorities can shift with less notice than they would at a larger, more established company.

This is the actual shape of working somewhere at this stage: It's genuinely energising for the right person and genuinely frustrating for the wrong one. If you want a place where the operating manual is already written, this might not be it – but if you want to help write it, this might be exactly it.

Why Hemab

At Hemab, your work ultimately connects back to something simple. People living with serious bleeding disorders get something they've never had before - the chance to prevent a bleed, instead of reacting to one after it happens. You'll be joining at a stage where individual decisions still carry real weight, and where your work can help turn promising science into a preventative treatment that actually reaches patients.

How we treat our people is meant to be an extension of how we think about patients: with care, honesty, and respect. We're still building the consistency to back that up across every hiring process, every time. We'd say that plainly instead of pretending otherwise. If any part of your experience with us falls short of it, tell us.

Hemab builds balanced candidate slates and assesses everyone against a single standard. If you need a reasonable adjustment at any stage of the hiring process, please tell us.

Hemab Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.