Director, Clinical Pharmacology (Immunology)

Allergan; South San Francisco (CA); On-site; USD 180,000 - 240,000; Full time

Benefits offered by this job

Paid time off

Long-term incentive programs

Job summary

AbbVie is seeking a Senior Clinical Pharmacology leader to guide PK/PD strategy and pharmacometric insights across drug development programs in a fast-paced environment. The role interfaces with R&D, Regulatory, and executive management to align scientific data with strategic decisions.

The successful candidate will lead teams, influence cross-functional plans, and ensure high-quality, timely deliverables across multiple projects in a dynamic organization.

Qualifications

• PhD with typically 7+ years of experience in PK/PD/Pharmacometrics
• Excellent interpersonal skills
• Knowledge across multiple therapeutic/functional areas
• Experience across development phases
• Leadership competencies in PK/PD and Pharmacometrics

Responsibilities

• Leads Clinical Pharmacology/PK/PD activities and major projects.
• Identifies issues and conducts risk assessments and contingency planning.
• Provides scientific and strategic consultation to R&D, Regulatory, and management.
• Reviews clinical protocols and regulatory documents for filings.
• May manage personnel and develop teams.

Skills

PK/PD

Pharmacometrics

Leadership

Project management

Cross-functional collaboration

Education

PhD in a relevant field

PharmD with relevant experience

MS in a related field

BS in related field

Job description

Company Description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, Xand YouTube.

Job Description

Communicates/presents key Clinical Pharmacology information/strategy to senior and executive management, regulatory agencies, and external peers. Supports strategic planning for drug development activities and projects to achieve departmental strategies, goals, and objectives. Utilizes scientific expertise to provide appropriate interpretation of data and relates implications of results to management. Serves as liaison to other departments/divisions for any study/project needs. Understands linkages across businesses and understands the impact of business decisions and solutions. May lead teams within Clinical Pharmacology and Pharmacometrics and accountable for effective performance of the teams.

Responsibilities

• Leads Clinical Pharmacology/PK/PD activities and multiple major projects. Assists R&D senior management in the selection of action plans that best meets drug development business objectives.


• Identifies issues and help with issue resolution. Conducts risk assessments and assists in development of contingency plans. Assures project remains in alignment with strategic objectives.


• Provides overall timelines to assess portfolio opportunities. Negotiates with other functional areas on project outcomes and deliverables to meet conflicting demands (time, cost, quality/performance).


• Provides scientific and strategic consultation to R&D, Regulatory, and all levels of management on critical decisions and development plans.


• Responsible for evaluating technical, scientific aspects of all AbbVie projects along with CLINICAL PHARMACOLOGY management. Reviews clinical protocols and scientific reports for regulatory filings and anticipates regulatory questions. Leads CLINICAL PHARMACOLOGY regulatory documents writing, submission and response to Regulatory agency comments.


• Independently conducts due diligence assessments, summarizes results and represents CLINICAL PHARMACOLOGY on business development teams.


• Identifies and develops process improvement initiatives and reviews recommendations with management for approval and sponsorship.


• Contribute to development of departmental goals. Influences strategic PK/PD decisions for the department.


• Performs functions and responsibilities with the highest regard for quality and timeliness. Maintains up-to-date knowledge of PK/PD data analysis, modeling and simulation methods and software.


• May manage personnel including development, mentoring, and effective delegation.

Qualifications

• PhD with typically 7+ years of experience or Pharm D with typically 9+ years of experience in a relevant field, MS or equivalent education with typically 15+ years of experience; BS or equivalent education and typically 17+ years of experience; (*relevant field includes experience with PK, PBPK, PK-PD, Pharmacometrics or systems pharmacology, Drug metabolism/Transporters)


• Excellent interpersonal skills


• Knowledge and experience in multiple therapeutic and/or functional areas


• Experience across range of development phases


• Knowledge of AbbVie and Pharma drug development processes


• Must have demonstrated leadership competencies in PK/PD, Biopharmaceutics, and Pharmacometric activities from planning, implementation through completion across multiple projects


• Scientific project leadership or related experience


• Project management skills such as scope management, progress tracking/driving as well as time management


• Participates in initiatives and advancement of CLINICAL PHARMACOLOGY


• Key Leadership Competencies:


• Knows the business and the cross-functional contributions needed to deliver results


• Persistent and resilient finds the way to move good ideas forward


• Acts respectfully yet courageously


• Connects unrelated concepts, generates original or unique ideas


• Influences colleagues to achieve cross-functional alignment


• Communicates openly and honestly with all colleagues


• Manages conflict and difficult conversations in a constructive transparent way

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law:

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.




• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.




• This job is eligible toparticipatein our long-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless and until paid andmay bemodifiedat the Company’s sole and absolute discretion, consistent withapplicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html