Director, Clinical Pharmacology

Biopharma Careers; Princeton (NJ); Hybrid; USD 202,000 - 245,000; Full time

Job summary

Bristol Myers Squibb is seeking a Director of Clinical Pharmacology to lead PK/PD strategies and model-informed drug development across development programs in Princeton, NJ. The role reports to the Senior Director and emphasizes cross-functional leadership, asset-team representation, and robust CP&P planning.

The candidate will mentor CP&P leads, guide study design, and collaborate with regulatory teams while advancing quantitative pharmacology and data-driven decision making in a dynamic,

Qualifications

• MS, PhD or PharmD in relevant field or a PharmD with clinical pharmacology research fellowship.
• 7+ years’ experience in Clinical Pharmacology and Pharmacometrics with drug development experience.
• In-depth knowledge of Clinical Pharmacology and Pharmacometrics.
• Strong written and oral communication skills for scientific presentations.
• Ability to work in a dynamic team-oriented environment.
• Mentorship and guidance to CP&P staff.
• Stakeholder management with leadership.
• Programming experience (e.g., NONMEM, R, WinNonlin, SAS).

Responsibilities

• Supervise and/or mentor CP&P leads.
• Contribute to compound development across development phases.
• Represent Clinical Pharmacology at asset teams.
• Input to Phase 2/3 study design and registrational strategy.
• Lead CP&P plan.
• Design CP studies and manage data analysis/reporting.
• Collaborate on cross-functional drug development teams and regulatory submissions.
• Engage with health authorities as CP&P SME.
• Lead CP&P initiatives and cross-functional workstreams.
• Support BD with external acquisitions.

Skills

PK/PD analysis

MIDD

Regulatory submissions

Cross-functional work

NONMEM

R

WinNonlin

SAS

Data visualization

Education

MS/PhD/PharmD in relevant field

Tools

NONMEM

R

WinNonlin

SAS

Job description

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”, a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

Position Summary

The Director, Clinical Pharmacology is responsible for leading the planning, implementation, and execution of clinical pharmacology strategies across one or more development programs, reporting to the Senior Director, Clinical Pharmacology & Pharmacometrics. This role drives trial- and program-level activities, applying pharmacokinetics/pharmacodynamics (PK/PD) principles and model-informed approaches to support decision-making throughout drug development. The Director partners cross-functionally to shape and deliver integrated development strategies, contributes as a key member of Clinical Pharmacology leadership and program teams, and ensures the development and execution of robust Clinical Pharmacology & Pharmacometrics (CP& P) plans aligned with compound strategy. In addition, the role fosters a collaborative and supportive environment that promotes scientific excellence and continuous learning.

Key Responsibilities:

• Supervise and/or mentor other CP& P leads as appropriate
• Independently contribute to compound development across various development phases
• Represent Clinical Pharmacology at asset teams at governance based on proficiency
• Provide input to Phase 2/3 clinical study design and registrational strategy
• Accountable for Clinical Pharmacology and Pharmacometrics Plan
• Lead design of Clinical Pharmacology studies and manages data analysis, interpretation, and reporting
• High proficiency in PK, PK/PD, and model informed drug development (MIDD) principles and analyses
• Collaborate on cross-functional drug development teams, regulatory submissions, and departmental initiatives; serves as Clinical Pharmacology subject matter expert
• Participate in interactions with health authorities; serve as Clinical Pharmacology subject matter expert
• Lead and participate in departmental initiatives and represent CP& P on cross-functional initiatives / workstreams / taskforces
• Work with Business Development teams and provide critical expertise to assess external acquisitions

Qualifications & Experience:

• MS, PhD or PharmD in relevant field or a PharmD with clinical pharmacology research fellowship
• Approximately 7+ years’ experience with demonstrated progression in Clinical Pharmacology and Pharmacometrics, including expertise in the general drug development process and in small molecule and/or biologic drug property characterization
• In-depth knowledge of current practices and issues in Clinical Pharmacology and Pharmacometrics
• Strong written and oral communication skills necessary to report on and deliver scientific presentations
• Demonstrate the ability to work in a dynamic team-oriented environment
• Manage and provide mentorship and guidance to staff and CP& P function
• Independently serve as the CP& P lead for one or more assets in the BMS drug development program
• Demonstrated stakeholder management with strong influence/leadership
• Programming experience is highly desired (e.g., NONMEM, R, and WinNonlin. SAS, Splus, etc.)
• Quantitative data analysis, POP PK/PD, and data visualization skills are highly desired
• #LI-Hybrid

Compensation Overview:

Cambridge Crossing: $226,130 - $274,021

Princeton - NJ - US: $201,910 - $244,666

The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully – carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.

Benefits:

• Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).
• U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year.
• Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.
• Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.

U.S.-based job seekers can explore full benefit offerings at https://careers.bms.com/benefits

How We Work

Where you work matters – because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail] . Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection .

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If this posting is missing required information required by local law or incorrect, contact BMS at [e-mail] with the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.

R1603445 : Director, Clinical Pharmacology