Director, Clinical Pharmacology

Recursion; New York (NY); On-site; USD 212,900 - 297,000; Full time

Benefits offered by this job

Annual bonus

Equity compensation

Comprehensive benefits package

Job summary

Recursion in New York is seeking a Clinical Pharmacology Leader to drive innovative strategies for drug development in oncology and rare diseases. You will be responsible for developing clinical strategies, designing studies, and collaborating across various teams to bring therapies to market faster.

The ideal candidate has a Ph.D./M.D. with substantial experience in drug development and proficiency in modeling software. The position offers the potential for remote work while maintaining strong teamwork and commitment to patients’ needs.

Qualifications

• 5-9+ years of experience in biotech/pharmaceutical drug development.
• Demonstrated success leading clinical pharmacology efforts.
• Ability to manage various analytical approaches for drug development.

Responsibilities

• Develop clinical pharmacology and pharmacometric strategies.
• Design clinical studies across various phases.
• Interface with cross-functional teams for project success.

Skills

Clinical pharmacology expertise

Pharmacokinetics

Regulatory submission experience

Modeling software proficiency (e.g., WinNonlin, NONMEM)

Collaboration skills

Oncology knowledge

Education

Ph.D. in Pharmaceutical Sciences or related discipline

M.D. with Clinical Pharmacology expertise

Pharm D with Clinical Pharmacology fellowship

Tools

WinNonlin

NONMEM

R

Job description

Your work will change lives. Including your own.

You will join an innovative and passionate clinical development team dedicated to improving the lives of patients suffering from devastating diseases. You will lead the innovative clinical pharmacology and pharmacometrics strategy and execution for a portfolio of rare disease and oncology clinical programs.

In this role, you will:

• Develop the clinical pharmacology and pharmacometric strategies to accelerate and support the overall product development plan. You’ll be the Clinical Pharmacology lead for various programs in clinical development, the representative for regulatory interactions, and propose innovative strategies to get therapies to patients faster.
• Design clinical studies. You’ll provide (clinical) pharmacology input on all clinical study designs, from Phase 1-3 and dedicated Phase 1 clinical pharmacology studies.
• Author review relevant clinical pharmacology sections for regulatory documents, including Investigator’s Brochures (IB), INDs, NDAs, and other regulatory submissions. Act as the clinical pharmacology expert during interactions with health authorities.
• Interface with cross-functional teams. You’ll work closely with clinical study teams, translational teams (DMPK, Translational Modeling and Toxicology), preclinical teams and due diligence teams to ensure clinical pharmacology-related considerations are addressed.
• Solve drug development questions/problems by overseeing and/or performing modeling and simulation with various tools to expedite decision making.

The Team You’ll Join

You will join the Development Sciences team within Recursion comprising clinical pharmacology, pharmacometrics, translational modeling and clinical biomarkers. The Development Sciences group sits within Recursion’s Clinical Development organization. Team members get to sit on both Discovery and Development projects and work in a seamless end-to-end environment at Recursion. The team collaborates closely with clinical development functions (clinical science, clinical operations, regulatory affairs, biostatistics, etc.), as well as discovery functions (DMPK, Biology, Chemistry and Translational Biomarkers).

The Experience You’ll Need

• Ph.D. in Pharmaceutical Sciences, Pharmacokinetics or related discipline, M.D with a Clinical Pharmacology expertise, or a Pharm D with a Clinical Pharmacology fellowship, with 5‑9+ years of experience in biotech/pharmaceutical drug development.
• Demonstrated success leading all clinical pharmacology related aspects of drug development.
• Ability to work closely with internal and external stakeholders to manage PK, PK‑PD, and PK‑safety analyses, including non‑compartmental analysis, population PK modeling, and PK‑PD modeling and simulations to support dose selection, exposure‑response and exposure‑safety analyses through various phases of drug development.
• Proficiency with WinNonlin, Monolix, NONMEM, R or other modeling software.
• Effective skills directed toward driving collaboration, achieving results, influencing, and resolving conflicts across internal and external stakeholders.
• Demonstrated experience responding to regulatory agency questions, preparing clinical pharmacology aspects of regulatory submissions and attending regulatory meetings.
• Highly motivated, decisive, and results‑oriented individual who is proactive, resourceful, and efficient with the flexibility and creativity to excel in and contribute to a rapidly growing drug discovery and development company.

Experience in oncology is preferred, but not an absolute requirement.

Working Location & Compensation

Making SLC or NYC your home base is ideal; however, we will consider remote work for this position. We ask that remote employees commit to regular on‑site visits for routine work and departmental events.

At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $212,900 to $297,000. You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package.

The Values We Hope You Share

• We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust.
• We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action.
• We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection.
• We move with urgency because patients are waiting. Speed isn’t about rushing but about moving the needle every day.
• We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy—leaders take accountability for decisive action, and teams own outcomes together.
• We are One Recursion. True cross‑functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities.

More About Recursion

Recursion (NASDAQ: RXRX) is a clinical‑stage TechBio company decoding biology to radically improve lives. Recursion is advancing a portfolio of differentiated investigational medicines across its wholly owned and partnered pipeline in oncology, rare disease, neuroscience, immunology, and other therapeutic areas with significant unmet need. Enabling its mission is the Recursion OS, an AI‑native, end‑to‑end drug discovery and development platform integrating biology, chemistry, and clinical development into a unified intelligence system. Powered by proprietary multimodal data, purpose‑built AI models, and bilingual teams fluent in both science and AI, the Recursion OS is designed to translate complex science into medicines that matter—faster, better, and at scale—for patients who are awaiting.

Recursion’s platform infrastructure is anchored in Salt Lake City, Utah and Milton Park, Oxfordshire, where its automated biology and chemistry laboratories generate proprietary data at industrial scale. Recursion also maintains offices in New York, Montréal, and London, three global hubs for talent and leadership at the intersection of AI and scientific innovation. Learn more at www.recursion.com, or connect on X and LinkedIn.

Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation.

Accommodations are available on request for candidates taking part in all aspects of the selection process.