Director, Business Development, Transactions

Alnylam Pharmaceuticals, Inc.; Cambridge, Northern (MA, KY); Hybrid; USD 180,000 - 240,000; Full time

Job summary

Alnylam Pharmaceuticals, Inc. in Cambridge, MA, seeks a Director of Business Development Transactions to lead deal sourcing, evaluation, and execution across licensing and strategic partnerships.

This role partners with R&D, Legal, Finance, and Commercial teams to shape value-creating collaborations that advance the portfolio. The ideal candidate has 8–10+ years in biopharma BD, strong deal-making, valuation, and negotiation skills, and a track record of driving complex transactions from

Qualifications

• Bachelor’s degree or higher in life sciences, business, or related fields.
• 8–10+ years in biopharma BD or related fields.
• 3–5 years direct BD deal experience with proven deals.

Responsibilities

• Identify and evaluate BD opportunities, including licensing and partnerships.
• Lead and support strategic, financial, and commercial assessments.
• Manage transaction execution: due diligence, term sheets, negotiation.
• Develop governance materials and senior leadership presentations.
• Collaborate with R&D, Commercial, Legal, and Finance to assess fit and risks.
• Expand external network with biotech/pharma partners.

Skills

Deal making

Valuation

Negotiation

Due diligence

Term sheets

Education

Bachelor’s degree

MBA or JD preferred

Job description

Director, Business Development, Transactions

Cambridge, MA

Overview

For the Director, Business Development Transactions role, we are seeking an experienced, high-performing, high-potential business development professional with strong business acumen and expertise in the biopharmaceutical industry. The ideal candidate brings experience across the full deal-making lifecycle, including opportunity evaluation, valuation, investment structuring, negotiation, and execution across a range of therapeutic areas, modalities, and stages of development.

The Director, Business Development will play a key role in driving the company’s growth strategy by identifying, evaluating, and executing strategic collaborations. This role will work cross-functionally to assess external opportunities, lead deal execution, and contribute to long-term portfolio strategy.

Success in the role requires excellent judgment, strong analytical capabilities, and ability to collaborate and influence internal and external stakeholders to drive and facilitate highly visible and time-sensitive BD projects.

Reporting to the Vice President, Head of Business Development, Transactions, this position is hybridand located inCambridge, MA.

Responsibilities

• Identify and evaluate potential business development opportunities, including in-licensing, out-licensing, and strategic partnerships.
• Lead and support strategic, financial, and commercial assessments of opportunities, including valuation and deal structuring.
• Manage transaction execution, including due diligence coordination, term sheet development, and negotiation.
• Develop materials for internal governance (e.g., investment committees) and senior leadership presentations.
• Collaborate closely with internal stakeholders (R&D, Commercial, Legal, and Finance) to assess strategic fit and risks.
• Maintain and expand external network with biotech/pharma companies, advisors, and other partners.
• Support alliance management activities post-deal execution, as needed.

Qualifications

• Bachelor’s degree required, with preference for a life science or business discipline; MBA, JD, or other advanced degree preferred; scientific background or strong aptitude to rapidly understand complex science and emerging technologies strongly preferred.
• At least 8-10+ years of relevant experience in the biopharmaceutical industry and related fields (including consulting or investment banking), including at least 3-5 years of direct business development experience, with a proven track record of leading deals.Detailed dealsheet required.
• Strong understanding of the drug development process and biotechnology/pharmaceutical industry dynamics including market trends, regulatory environment, the macro deal making environment, and their business impact.
• Ability to integrate scientific knowledge into business cases, including the analysis and interpretation of commercial forecasts, P&Ls, risk assessments, and other financial valuation methodologies, alongside strong term sheet development, project management, and contract negotiation skills.
• Ability to synthesize complex information into clear strategic insights, frame strategic tradeoffs, and influence decision-making, as well as strong attention to detail and execution rigor.
• Excellent communication, presentation, and problem-solving skills and executive presence, with the ability to influence stakeholders at all levels, internally and externally.
• Highly collaborative, adaptable, and effective in a fast-paced, evolving environment with competing priorities.

About Alnylam

We are the leader in RNAi therapeutics– a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

The pay range below reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.