Director, Biomarkers and Companion Diagnostics

BeOne Medicines; San Carlos (CA); On-site; USD 177,000 - 237,000; Full time

Job summary

BeOne Medicines in California seeks a Director of Clinical Biomarkers to lead biomarker strategies across the clinical pipeline, partnering with cross-functional teams, collaborators, and vendors.

You will translate emerging biomarker science into actionable plans for patient selection and precision medicine, with expertise in biomarker platforms and translational research to influence program strategy at a global scale.

Qualifications

• PhD in a life science field or equivalent.
• 7+ years in biotech/pharma with 3+ years in biomarker R&D or strategy.
• Deep biomarker expertise in translational research, preferably hematology/oncology/immunology; AML preferred.
• Ability to develop and lead biomarker strategies informing development.
• Knowledge of CDx development and regulatory requirements.
• Experience evaluating novel biomarker technologies.
• Proven ability to influence across cross-functional and global teams.

Responsibilities

• Develop and implement biomarker strategies.
• Assess novel biomarker platforms.
• Support clinical protocol development.
• KOL & collaborator engagement for biomarkers development.
• Build relationships with internal and external experts.
• Identify continuous process improvement opportunities.
• Develop, track, execute and report on goals and objectives.
• Support budget planning and management.
• Be accountable for compliant business practices.

Skills

Biomarker strategy

Cross-functional leadership

Translational research

Stakeholder engagement

Communication

Education

PhD in Life Sciences

Job description

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.

The Director of Clinical Biomarkers will provide scientific and strategic leadership for biomarker activities across BeiGene’s clinical pipeline. In partnership with cross-functional teams, external collaborators, and vendors, the Director will develop and execute biomarker strategies across preclinical and clinical programs, including scientific objectives, experimental validation, timelines, and budgets.

The Director will also evaluate and advance novel biomarker technologies, translating emerging science into actionable strategies that support clinical development, patient selection, and precision medicine. The successful candidate will bring deep scientific expertise in biomarker platforms, strong communication and leadership skills, demonstrated scientific impact, and the ability to influence program strategy across a complex, global organization.

Responsibilities

Essential Functions of the job:

• Lead, manage and/or develop the following areas collaboratively (internally and/or through third-party):
• Development and implementation of biomarker strategies
• Assessment of novel biomarker platforms
• Support of clinical protocol development
• KOL & collaborator engagement for biomarkers development
• Build strong relationships with internal and external experts
• Identify continuous process improvement opportunities
• Develop, track, execute and report on goals and objectives
• Support budget planning and management
• Be accountable for compliant business practices

Qualifications/Requirements

• Advanced degree (e.g., PhD) in a clinical or scientific discipline, or equivalent education, training, and experience.
• 7+ years of biotechnology/pharmaceutical industry experience, including 3+ years in biomarker research, development, or strategy.
• Deep expertise in clinical biomarkers and translational research, preferably in hematology, oncology, or immunology; AML experience strongly preferred.
• Demonstrated ability to develop and lead biomarker strategies that inform clinical development and key program decisions.
• Strong understanding of biomarker implementation, including scientific, operational, budget, and timeline considerations.
• Working knowledge of companion diagnostic (CDx) development and relevant regulatory requirements.
• Experience evaluating and applying novel biomarker technologies and platforms, particularly in hematology.
• Proven ability to influence and lead across cross-functional and global teams, align stakeholders, and communicate effectively with senior leadership.

Capabilities And Competencies

• Scientific and technical expert on biomarkers to support clinical development
• Successful and superior influencing skills across all levels of the organization and external collaborators
• Values based collaborator – respectful, accountable and collaborative
• Ability to build working relations throughout the organization and with business partners to achieve business goals
• Impactful written and verbal scientific communication
• Problem solving and risk‑mitigation skills
• Strategic and creative thinker
• Strong time management and organizational skillsAbility to manage multiple projects in a fast‑paced environment
• Appreciation of diversity and multiculturalism

Supervisory Responsibilities

• None listed

Education Required

• PhD in one of the Life Science areas (Molecular & Cellular Biology, Biochemistry, Immunology etc).

BeOne Global Competencies

When we exhibit our values of Patients First, Collaborative Spirit, Bold Ingenuity and Driving Excellence, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

• Fosters Teamwork
• Provides and Solicits Honest and Actionable Feedback
• Self‑Awareness
• Acts Inclusively
• Demonstrates Initiative
• Entrepreneurial Mindset
• Continuous Learning
• Embraces Change
• Results‑Oriented
• Analytical Thinking/Data Analysis
• Financial Excellence
• Communicates with Clarity

Global Competencies

When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

• Fosters Teamwork
• Provides and Solicits Honest and Actionable Feedback
• Self‑Awareness
• Acts Inclusively
• Demonstrates Initiative
• Entrepreneurial Mindset
• Continuous Learning
• Embraces Change
• Results‑Oriented
• Analytical Thinking/Data Analysis
• Financial Excellence
• Communicates with Clarity

Salary Range: $176,600.00 - $236,600.00 annually

BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness.

We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact [e-mail].