Digital Biomarker Science & Technology Neuroscience Lead

Roche; Indianapolis (IN); On-site; USD 216,000 - 288,000; Full time

Job summary

Roche Information Solutions in Basel seeks a Scientific Product Owner for digital biomarker solutions within the dBM and RPM chapters. You will lead end-to-end scientific research, coordinate cross-disciplinary teams, and define the scientific roadmap for remote patient monitoring in clinical research and care.

You have a Ph.D. with 10+ years in pharma/digital health, strong publication record, and proven senior stakeholder management. Join Roche to advance healthcare with sensor-based endpoints.

Qualifications

• Ph.D. or equivalent in Life Sciences with 10+ years in pharma/digital health.
• Proven track record of high-impact publications in peer-reviewed journals.
• Experience leading external collaborations and senior stakeholders in a matrix organization.

Responsibilities

• Act as scientific product owner for digital biomarker solutions for Roche and external customers.
• Oversee end-to-end scientific research & development and the scientific roadmap.
• Lead interdisciplinary project teams to design and implement digital biomarker solutions addressing unmet measurement needs.
• Drive the regulatory strategy for digital endpoints and maintain scientific credibility with stakeholders.

Skills

Publications in high-impact journals

Stakeholder management

Scientific product management

Sensor data / digital biomarkers

Leadership in matrix organizations

Cross-functional collaboration

Education

Ph.D. or equivalent in Life Sciences

Job description

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

Who we are

We, the Digital Biomarker (dBM) and Remote Patient Management (RPM) Chapter in Roche Information Solutions, are an integrated team of scientists, technologists, data analysts and operations experts, that leverages mobile technologies like smartphones and wearables to bring the power of sensor measures to patients everywhere: in clinical drug trials and clinical care. We drive research, workflows and analytics for Digital Biomarkers and Remote patient management in Roche Information Solutions. Together with our partners, we invent, design and deliver solution capabilities, products and services for better clinical research and improved healthcare outcomes. We co-create innovative digital remote monitoring concepts for sensitive and meaningful drug development endpoints, implement them in technology solutions, develop health related outcome measures with the data, seek community and regulatory acceptance of corresponding endpoints and offer them to Biopharma companies and research institutes for use in clinical trials. We are establishing the scientific foundations for disease monitoring and screening solutions in clinical practice and enable patients and healthcare providers to leverage the power of sensor data for better outcomes in the management of neurological disease, diabetes and others.

Here's what we're looking for:

• Collaborate with the International Product Manager for Chronic Remote Care Management to leverage scientific data insights and customer feedback to discover, develop and scale a product that is desirable, feasible and viable
• Together with the International Product Manager for Chronic Remote Care Management, develop and cultivate networks with key opinion leaders for Neuroscience as well as with key stakeholders within the company
• Partner with a broad stakeholder community of patients, care givers, physician and other experts to create scientific digital health solutions
• Act as scientific product owner for a set of digital biomarker solutions for Roche and external customers with needs in areas of Disease understanding / Drug portfolio decision-making (phase I-II) / Regulatory treatment approval (phase III-IV) / Clinical trial participant selection / Clinical care
• Oversee end-to-end scientific product research & development and the scientific roadmap
• Scientifically lead large interdisciplinary project teams that identify, design, develop and implement the scientific digital biomarker solutions to address the unmet measurement needs
• Drive the regulatory strategy for digital endpoint endorsement and qualification
• Drive scientific community acceptance of digital measures and maintain a strong network of collaborators spanning industry and academia
• Develop scientific core messages for product marketing
• Represent RIS scientifically in pre-sales conversations on Remote Patient Management and Digital Biomarker products
• Plan, initiate and co-author high-profile scientific publications and posters and represent Roche at relevant high-profile conferences
• Grow your influence as a respected scientific digital biomarker expert and advocate in the research and development community at Roche and externally through cross-industry task forces, communicating results at conferences and in peer-reviewed publications
• Drive the scientific foundations of clinical use scenarios based on sensor-measurements to improve outcomes for patients as well as the efficiency of healthcare delivery

Who you are

• University degree (Ph.D. or equivalent) in Life Sciences or related field with a minimum of 10 years related experience in the pharmaceutical and digital health industry
• Track record of writing compelling publications in high impact, peer-reviewed journals
• Proven experience with senior stakeholder management and external collaborations
• Deep scientific product management experience in a large Pharma or Medtech company
• Deep experience in the area of sensor data and digital biomarker development
• Provable experience leading in a matrix setup, recognized for embracing new ways of leading and working, with strengths in coaching and fostering a collaborative environment
• Transparent communicator and able to apply effective empowering leadership
• Previous clinical experience in chronic disease management and Neuroscience (especially Parkinson's Disease, Huntington's Disease, Multiple Sclerosis)

Should you have these additional nice-to-have skills, you are the ideal team member we are searching for

• Comprehensive understanding of the current state of drug development for Parkinson's and Huntington's Disease
• In-depth knowledge of the clinical endpoint landscape and associated challenges in Parkinson's and Huntington's Disease
• Overview of existing digital biomarker approaches for these diseases
• Experience with developing digital outcome measures
• FDA/EMA regulatory interactions or regulatory consortia regarding clinical drug development and novel drug development endpoints

Where pay transparency applies, details are provided based on the primary posting location. For this role, the primary location is Basel. If you are interested in additional locations where the role may be available, we will provide the relevant compensation details later in the hiring process.

Who we are

A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let's build a healthier future, together.

Roche is an Equal Opportunity Employer.

Roche is an equal opportunity employer and strictly prohibits unlawful discrimination based upon an individual's race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, mental/physical disability, medical condition, marital status, veteran status, or any other characteristic protected by law.