Developability & Early CMC Director — Onsite

PineTree Therapeutics Inc; Cambridge (MA); On-site; USD 100,000 - 250,000; Full time

Job summary

A biotech company in Cambridge is seeking a Director of Developability and Early CMC Development. This full-time position involves leading early CMC development for monoclonal and multispecific antibodies, requiring a PhD and over 10 years of relevant experience. Candidates should possess strong analytical method development skills and managerial experience. Competitive compensation ranges from $100,000 to $250,000 per year, with the possibility to convert to full-time based on performance.

Qualifications

• 10+ years of experience in advancing biological molecules from late research to CMC development.
• Experience in analytical method development and optimization for biological characterization.
• Demonstrated expertise in designing and validating purification techniques.

Responsibilities

• Oversee development of late-stage drug candidates with analytical and developability screening.
• Establish analytical methods for therapeutic antibody development.
• Collaborate with cross-functional teams on clinical development strategies.

Skills

Interpersonal and communication skills

Analytical method development

Organization and problem-solving

Managerial experience

Education

PhD or advanced degree in relevant scientific discipline

Tools

UPLC-MS

LC-MS

RP-HPLC

HIC-HPLC

CEX-HPLC

Job description

A biotech company in Cambridge is seeking a Director of Developability and Early CMC Development. This full-time position involves leading early CMC development for monoclonal and multispecific antibodies, requiring a PhD and over 10 years of relevant experience. Candidates should possess strong analytical method development skills and managerial experience. Competitive compensation ranges from $100,000 to $250,000 per year, with the possibility to convert to full-time based on performance.