Deputy Director Manufacturing Operations

BioSpace; Pearl River (NY); On-site; USD 180,000 - 240,000; Full time

Benefits offered by this job

Healthcare benefits

Parental leave

Career growth opportunities

Job summary

Sanofi is seeking a Deputy Director of Manufacturing Operations in Pearl River, NY. You will lead upstream and downstream manufacturing activities, drive readiness, and ensure GMP/GDP compliance across the site. The role requires strong Lean methods, RCA, and cross-functional collaboration with Process Development, Quality, and Engineering.

You will mentor teams, manage budgets, and help shape strategic initiatives in a fast-paced biopharma environment.

Qualifications

• Bachelor’s degree in engineering, science, life sciences, business, or related field.
• 5–7 years of pharmaceutical or biopharmaceutical manufacturing experience.
• 5+ years of progressive leadership in a GMP manufacturing environment.
• Strong GMP and GDP knowledge and Lean methodologies.
• Proven root cause analysis with corrective actions.
• Experience with performance management routines (e.g., +QDCI).
• Conflicts management and prioritization in a fast-paced setting.
• Excellent communication and stakeholder management.
• Understanding of cell growth and propagation in biopharma manufacturing.

Responsibilities

• Directly manage manufacturing teams supporting upstream and downstream operations.
• Ensure manufacturing areas are safe and production-ready; monitor schedules for targets and compliance.
• Lead a culture of accountability, collaboration, and continuous improvement.
• Coach and develop team members at all levels; manage cross-function relationships.
• Lead deviation investigations and RCA to resolve manufacturing deviations.
• Collaborate with Process Development, Quality, Supply Chain, and Engineering for tech transfers and improvements.
• Identify and elevate risks to readiness, supply continuity, or compliance; assist budget/resource planning.

Skills

Leadership

GMP Knowledge

Lean Manufacturing

Root Cause Analysis

Performance Management

Conflict Management

Communication

Stakeholder Management

Cell Culture Understanding

Education

Bachelor's degree

Job description

Job Title: Deputy Director Manufacturing Operations

Location: Pearl River, NY

About The Job

Join a global network that powers how Sanofi delivers seamlessly, purposefully, and at scale. In Manufacturing & Supply, youll help reimagine how life-changing treatments reach people everywhere, faster.

About Sanofi

Were an R&D-driven, AI-powered biopharma company committed to improving peoples lives and delivering compelling growth. Our deep understanding of the immune system and innovative pipeline enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve lives.

Main Responsibilities

Leadership & Team Management

• Ensure all areas and employees are safe at all times
• Directly manage manufacturing teams supporting upstream and downstream Flublok drug substance operations
• Foster a high-performance culture grounded in accountability, collaboration, and continuous improvement
• Provide coaching, mentorship, and professional development to team members at all levels
• Effectively manage conflict within and across teams to maintain a productive and respectful work environment
• Drive a strong sense of urgency in day-to-day operations while maintaining quality and compliance standards

Manufacturing Readiness & Operations

• Ensure manufacturing areas are consistently ready for scheduled production activities
• Oversee upstream and downstream manufacturing processes, including cell culture, protein production, clarification, purification, and related unit operations
• Monitor and manage production schedules to meet output targets while maintaining compliance with all applicable standards
• Ensure all equipment, materials, documentation, and personnel are in a state of readiness prior to manufacturing execution

Quality, Compliance & Continuous Improvement

• Ensure all manufacturing activities are conducted in strict accordance with GMP (Good Manufacturing Practice) and GDP (Good Documentation Practice) requirements
• Lead and support deviation investigations, applying structured root cause analysis (RCA) methodologies to identify, document, and resolve manufacturing deviations
• Champion Lean manufacturing principles and defect identification practices to eliminate waste and drive process efficiency
• Implement and sustain performance management routines, including +QDCI (Quality, Delivery, Cost, Involvement) metrics and visual management tools
• Partner with Quality Assurance and Regulatory Affairs to support inspections, audits, and regulatory submissions as needed

Strategic & Cross-Functional Collaboration

• Collaborate with Process Development, Quality, Supply Chain, and Engineering teams to support technology transfers, process improvements, and capacity planning
• Represent manufacturing in cross-functional forums and contribute to site-level strategic initiatives
• Identify and elevate risks to manufacturing readiness, supply continuity, or compliance in a timely manner
• Support the development and management of departmental budgets and resource planning

About You

Basic Qualifications

• Bachelors degree in engineering, Science, Life Sciences, Business, or any related field.
• 5 -7 years of experience in pharmaceutical or biopharmaceutical manufacturing.
• 5+ years of progressive, hands‑on leadership experience in a GMP manufacturing environment, with an expectation to interact with and solve problems at the shop floor level.
• Strong working knowledge of GMP and GDP regulations and their application in a manufacturing environment
• Proven expertise in Lean manufacturing methodologies (5s, Gemba Problem Solving, Daily Capacity Management) and defect identification/reduction.
• Demonstrated ability to perform thorough root cause analysis on manufacturing deviations and implement effective corrective actions.
• Experience with performance management routines, including +QDCI or equivalent operational excellence frameworks.
• Strong conflict management skills with the ability to navigate interpersonal and team dynamics effectively.
• Demonstrated sense of urgency and ability to prioritize and respond decisively in a fast-paced manufacturing environment
• Excellent communication, organizational, and stakeholder management skills
• Understanding of cell growth and propagation principles as they apply to biopharmaceutical drug substance manufacturing

Preferred Qualifications

• Advanced degree (MS, MBA) in Life Sciences, Engineering, Business Administration or related technical field.
• Hands‑on experience with one or more of the following technologies:
• Single Use Systems
• Chromatography
• Tangential Flow Filtration
• Stainless Steel Systems (Fermenters and Bioreactors)

Why choose us?

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether its through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well‑crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention andwellness programs and at least 14 weeks gender-neutral parental leave.
• Shape the future of medicine and vaccine delivery with cutting‑edge technology, ensuring seamless launches and a resilient global supply.
• Power industry‑leading performance by leveraging digital, data, and AI‑driven innovation at speed and scale
• Transform lives worldwide by delivering life‑changing treatments anywhere, anytime.

Sanofi US Services and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs, and additional benefits information can be found here.