Data Scientist: Real‑World Evidence & Biostatistics

Calyxo, Inc.; United States; On-site; USD 135,000 - 155,000; Full time

Benefits offered by this job

Stock options

401(k) and healthcare

Paid vacation

Job summary

Calyxo, Inc. is seeking a Data Scientist to transform real-world, clinical, and preclinical data into reliable datasets, analyses, and insights that support research and cross-functional business needs.

The ideal candidate brings strong hands-on data science and statistical skills, with the ability to translate research questions into fit-for-purpose datasets and analytical approaches. This role will support real-world data initiatives and the statistical execution of preclinical and clinical

Qualifications

• Bachelor’s degree in a quantitative field plus 7 years of experience; or Master’s degree plus 5 years.
• Practical experience using R to prepare, analyze, visualize, and validate complex datasets.
• Experience translating a research question into a well-defined dataset, analysis plan, and transparent, reproducible analytical workflow.
• Experience with statistical analysis of clinical, preclinical, observational, or other health-related data.
• Working knowledge of study design, endpoint definition, analysis planning, and interpretation of study data.

Responsibilities

• Translate research and business questions into cohort definitions, data requirements, analytic plans, and clear deliverables.
• Work with real-world data sources (EHR, claims, clinical data) to assess data availability, provenance, quality, and suitability for analysis.
• Build, validate, and maintain reproducible workflows for data extraction, transformation, and analysis-ready datasets.
• Develop, validate, and document repeatable workflows for structured clinical data and unstructured notes, including NLP where appropriate.
• Support real-world evidence and post‑market analyses, including trend assessments and subgroup analyses.

Skills

R programming

Data wrangling

Statistical analysis

Education

Bachelor’s degree in data science, statistics, biostatistics, computer science, epidemiology, public health, or a related quantitative field

Master’s degree in a related field

Tools

SAS

Python

SQL

Job description

Calyxo, Inc. is seeking a Data Scientist to transform real-world, clinical, and preclinical data into reliable datasets, analyses, and insights that support research and cross-functional business needs.

The ideal candidate brings strong hands-on data science and statistical skills, with the ability to translate research questions into fit-for-purpose datasets and analytical approaches. This role will support real-world data initiatives and the statistical execution of preclinical and clinical