Data Management Specialist II, Center for Human Brain Variation

Broad Institute of MIT and Harvard; Cambridge (MA); On-site; USD 70,000 - 94,000; Full time

Benefits offered by this job

Medical benefits

Dental and vision insurance

Life and disability insurance

401(k) retirement plan

13+ paid holidays

Job summary

The Broad Institute of MIT & Harvard is seeking a Data Management Specialist to support the Center for Human Brain Variation with high-volume single-cell data across multiple management systems. You will collaborate with project teams, manage data quality, and coordinate large dataset submissions to NeMO and NDA.

You will present quality metrics to scientists, work with engineers to optimize workflows, and help ensure timely deliverables while adhering to NIH data sharing policies.

Qualifications

• Bachelor’s degree in bioinformatics, computer science or a related field.
• 1-2+ years in a high-data-volume scientific environment; experience with reports and data workflows.
• Experience with databases and data management systems.
• Proficiency in scripting (Python or R).
• Linux familiarity; Bash preferred.
• Familiarity with cloud platforms (Google Cloud or AWS).
• Experience with Nextflow a plus; ability to learn new tools.

Responsibilities

• Advance large single-cell and spatial transcriptomic datasets through analysis workflows.
• Plan and execute data quality assessments for high-volume data.
• Present data quality metrics to scientific teams and at lab meetings.
• Communicate complex metrics to stakeholders with varied backgrounds.
• Coordinate submission of large datasets to data repositories (NeMO, NDA).
• Ensure single-cell libraries are tracked and quality-checked in NIMP.
• Collaborate with consortium members and sites on data releases.
• Work with software engineers to optimize analysis workflows for high data volume.
• Produce reports summarizing data usage and storage needs.
• Support the managing director with progress reports on data deliverables.

Skills

Python

R

Linux

Bash

Google Cloud

AWS

Nextflow

Single-cell tech

Data reporting

Education

Bachelor's degree in bioinformatics or related

Job description

The Broad Institute of MIT & Harvard is looking for an outstanding Data Management Specialist to provide comprehensive data management support for the Center for Human Brain Variation. The mission of the Center is to address an unmet need in cell census research: to understand the cell-type-specific mechanisms and larger tissue-level biological principles that generate meaningful variation in brain biology among people.

We are looking for a data management professional who is passionate about the mission of the Broad Institute and Center for Human Brain Variation. The ideal candidate will be highly collaborative and be prepared to lead and take direction as part of cross functional project teams.

The candidate must be comfortable working with a high volume of single-cell datasets across multiple data management systems.

Responsibilities

• Advance large single-cell and spatial transcriptomic datasets through analysis workflows.
• Plan and execute analytical processes by which high-volume experimental data are quickly assessed for quality.
• Present key data quality metrics to scientific teams generating the data; provide regular updates to the project team at weekly lab meetings.
• Communicate complex quality metrics to stakeholders with different areas of expertise; develop presentation content appropriate for a variety of audiences.
• Coordinate the submission of large datasets to the appropriate data repositories (ie NeMO, NDA) and other key constituencies, while ensuring compliance with applicable policies such as the NIH Data Sharing Policy.
• Work with project managers and researchers to ensure that single-cell libraries are tracked and reviewed for quality in NIMP (Neuroanatomy-anchored Information Management Platform).
• Serve as the main point of contact for consortium data releases, working in close collaboration with other consortium members and sites.
• Work with software engineers toward optimization of analysis workflows for high-data-volume experiments.
• Collaborate closely with laboratory and data analysis teams to support overall project deliverables, ensuring deliverables are met on time.
• Provide a variety of reports summarizing research data usage. Assist the lab’s scientific teams in utilizing disk and cloud storage in cost-efficient and time-efficient ways.
• Assist the managing director with the preparation of progress reports that involve data deliverables.

Qualifications

• Bachelor’s degree in bioinformatics, computer science or a related field
• 1-2 + years of experience working in a high-data-volume scientific environment, including experience advancing data sets through complex analysis workflows
• Experience working with databases
• Working knowledge of at least one scripting language (ie. Python, R)
• Experience working in Linux operating system, including working knowledge of Bash, is preferred
• Familiarity with Google Cloud and/or AWS (Amazon Web Services)
• Experience with NextFlow a plus
• Ability to thrive in a fast-paced rapidly changing environment
• Excellent organizational skills and ability to prioritize tasks thoughtfully
• Expertise in using Google Docs and Google Sheets
• Experience creating and managing reports (e.g. trend analysis, summary reports)
• Familiarity with single-cell technologies is preferred; for example, understands the entire 10X workflow from sample preparation through data analysis
• Experience working with sequencing output data, including BAM files and fastqs, is strongly preferred
• Comfortable learning new software and technologies
• Must possess a demonstrated ability to interact with an interdisciplinary group of both professional staff and academic trainees; including project managers, data analysts, computational scientists, and laboratory scientists

Pay Range: $70,000.00/yr - $94,000.00/yr

The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.

At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.

The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

Should you need a reasonable accommodation to complete the application or interview process, please contact [e-mail] for assistance.