Data Architect

Lindus Health; United States; Hybrid; USD 130,000 - 180,000; Full time

Benefits offered by this job

Competitive salary

Stock options

27 days annual leave

Health insurance

Wellness allowance

Learning & Development funds

Parental leave

Company events

Job summary

Lindus Health seeks a Data Architect to own end-to-end study data design and delivery on Citrus, ensuring analysis-ready data through automated checks and validation. You’ll lead data strategy with Clinical Operations, Biostatistics, and Product, shaping automation to improve data quality and speed.

You’ll design data capture, implement edit checks, and drive data integrity while aligning with GCP, ICH E6, and 21 CFR Part 11. A startup mindset is essential.

Qualifications

• 5+ years in clinical data management or trial platform design.
• Experience with study setup, data review, and database lock.
• Ability to design data capture on an EDC platform and specify edit checks.
• Programming experience or willingness to learn Python, R, or SQL.
• Knowledge of CDISC standards; CDASH and SDTM familiarity preferred.
• Experience with external data transfers and data reconciliation.
• Understanding of GCP, ICH E6, and 21 CFR Part 11.
• Cross-functional collaboration across Clinical Operations, Biostatistics, and Product.

Responsibilities

• Own assigned studies end to end from planning to database lock.
• Design Citrus study specifications and AI-assisted edit check logic.
• Assess feasibility and flag complexity and risk early.
• Manage the full query lifecycle with sites.
• Lead proactive, risk-based data review with automated checks.
• Use scripting and AI tools to automate data review and flag anomalies.
• Handle fixes and change requests with testing and sign-off.
• Perform ongoing safety data review and MedDRA/WHODrug coding with the medical team.
• Build reports using Python, R, and SQL; deliver on schedule.
• Ensure compliance with regulations; support auditors and inspectors.
• Report bugs and feed insights to Product to improve Citrus.

Skills

Clinical data management

Study design

SQL

Python

R

CDISC standards

SDTM familiarity

Data transfers

GCP

21 CFR Part 11

Automation & AI

Cross-functional collaboration

Tools

Python

SQL

R

Job description

Our mission

Great science regularly stalls in the clinic, not because the science is wrong, but because the company behind it lacks the capital, infrastructure, or focus to take it all the way through. Today’s clinical-stage biopharma model is broken, and as a result promising treatments never reach patients.

Our mission is to fix this: we're building the next generation of biopharma by in‑licensing clinical‑stage therapeutic assets and developing them through Lindus Health’s integrated, technology‑first clinical trial infrastructure. We’re a new initiative, but we’re building on a proven foundation - the same infrastructure that has delivered 82% of Lindus Health’s sponsor trials on or ahead of timeline, across 40+ completed trials across the US and Europe.

We’re in‑licensing 5-7 clinical‑stage, typically Phase‑2‑ready assets, funded directly from Lindus Health’s balance sheet. We’re targeting deal close on our first assets through 2026, with first trials launching in H1 2027.

About the role

The Data Architect owns assigned studies end‑to‑end, taking full responsibility for both the design of the database on Citrus and the quality of the data it produces, from study planning through database lock. The role designs with the final analysis in mind, writes code where manual review would slow delivery, and designs the edit checks and validation that prevent issues before they make their way downstream. The Data Architect is the technical and data lead for assigned studies and works with Clinical Operations, Biostatistics, Programme Directors, and Product to ensure each study captures the data its scientific objectives require.

One person owns the database from study planning through lock, so the design and the data it produces never drift apart. The role also shapes how data delivery on Citrus develops, identifying where manual work can be automated.

About you

• You have around 5+ years of experience across clinical data management and/or trial platform design, with hands‑on involvement in study setup, data review, and database lock

• You can design a study’s data capture on an EDC platform and define its specification: you understand edit checks and validation, and you can see how a design decision today could become a data quality problem later

• You work with data programmatically, or are ready to build that skill quickly: Python, R, or SQL are used daily in this role, and you are expected to learn them on the job if you do not already have them

• You have working knowledge of CDISC standards, particularly CDASH, with SDTM familiarity a plus, and you design with analysis‑ready data in mind

• You have experience with external data transfers and reconciliation

• You understand GCP, ICH E6 and 21 CFR Part 11 and apply them in day‑to‑day decisions

• You apply AI and automation responsibly to improve the quality and speed of data work in a regulated setting

• You have a track record of working well across functions, especially Clinical Operations, Biostatistics, Programme Directors, and Product

• You thrive in a startup environment that challenges the norms of typical biotechs, with high agency and a bias for action

• You are passionate about our mission: changing how the healthcare industry operates and how new health treatments are developed

What you’ll focus on

• Own your assigned studies end‑to‑end, from defining critical data items and the data management plan through to database lock

• Own the design of your studies on Citrus, utilizing AI combined with your expert review to translate protocol requirements into a specification and edit check logic that capture clean, analysis‑ready data, and sign off that the design meets the protocol before go‑live

• Assess feasibility and flag complexity and risk early, where a design choice could affect data integrity, participant safety or study endpoints

• Manage the full query lifecycle from generation through resolution, working directly with sites

• Lead proactive, risk‑based data review, automated where possible, to keep key study milestones on track, building repeatable checks rather than one‑off reports

• Use scripting and AI tooling day‑to‑day to automate data review, flag anomalies, and surface issues earlier, applied responsibly within validation, GCP and 21 CFR Part 11 expectations

• Own fixes and change requests on your own studies during conduct, assessing their impact and the level of testing and sign‑off required

• Perform ongoing safety data review and facilitate medical coding (MedDRA, WHODrug) with the medical team

• Build reports using programmatic data access (Python, R, SQL), delivered accurately and on schedule

• Conduct all activities in line with relevant regulations and Lindus SOPs, keep study documentation to a standard that holds up under audit or inspection, and support auditors and inspectors on your studies where needed

• Report bugs and usability issues, and feed operational insight back to Product to improve how Citrus supports data delivery

What we offer (US)

Make an impact across all areas of our business and fix one of the world's most broken industries.

• Competitive salary, plus meaningful stock options
• 27 days annual leave in addition to 11 National Holidays
• Health insurance coverage through our PEO Trinet
• $40 monthly wellness allowance, which you can spend on a wellhub membership, or wellness activities and expenses of your choice!
• Enhanced Parental Leave: 16 weeks full pay for primary caregiver and 6 weeks full pay for secondary caregiver
• $2,000 Learning and Development allowance each year to put towards courses, certifications, and development
• Regular whole company and team events, both in person and virtually
• Access to gym and retail discounts through our benefits platform Happl
• Monthly lunch voucher for our remote teams
• Charity events and fundraising opportunities through our charity partnership with the Forward Trust

What we offer (UK)

Make an impact across all areas of our business and fix one of the world's most broken industries.

• Competitive salary, plus meaningful stock options
• Flexible working: We have an incredible office near London Bridge and encourage people to work 3 days per week from the office
• 30 days annual leave in addition to Bank Holidays, resulting in 39 paid days off per year
• £60 monthly wellness allowance, which you can spend on our company health insurance scheme through AXA, a wellhub membership, or wellness activities and expenses of your choice!
• Enhanced Parental Leave: 16 weeks full pay for primary caregiver and 4 weeks full pay for secondary caregiver
• £1,000 Learning and Development allowance each year to put towards courses, certifications, and development
• Regular whole company and team events, both in person and virtually
• Access to gym and retail discounts through our benefits platform Happl
• A well-stocked pantry and drinks fridge, Monday breakfast spread and catered team lunch on a Thursday for the UK office every week!
• Cycle-to-work scheme and other salary sacrifice options available
• Charity events and fundraising opportunities through our charity partnership with the Forward Trust

Our Hiring Process

We believe hiring should be transparent, respectful of your time, and give you a real feel for what Lindus Health is like. Here's what to expect:

Online Critical thinking test via TestGorilla (20 mins)
Once your invited to meet with us you'll be send a booking like as well as a link to TestGorilla's platform. This is a 2 part first stage.

Initial conversation with Sophie, Head of Talent (30 mins)
Get to know each other, discuss the role, and answer any questions you have

Meet the hiring manager with Tatiana, AD Data(30 mins)

Talk through the role in more detail and your experience.

Functional interview with two members of the Data team (60 mins)
Deep dive into your experience and how you'd approach key challenges

Values interview with our CEO, Meri and Veronica, VP Data (30 mins)
A chance to get to know each other and explore how our values align

We'll arrange at least one interview in‑person at our office if you are UK based so you can meet more of the team and get a feel for our environment - usually the final values stage.

We will only contact you from lindushealth.com email addresses. Please check the spelling of emails which appear to come from Lindus carefully before responding. We will never ask for your financial information over email.

We are an equal opportunity employer committed to building a diverse and inclusive workforce. We evaluate all candidates based solely on their skills, experience, and qualifications relevant to the role. We do not discriminate on the basis of race, ethnicity, religion, gender, gender identity, sexual orientation, age, disability, veteran status, or any other legally protected status