Cytogenetic Technologist
University of Colorado Anschutz
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Job summary
University of Colorado Anschutz in Aurora, CO, is seeking a Cytogenetic Technologist at an intermediate to senior level to join the clinical cytogenetics team. The role performs high-complexity testing including chromosome analysis, FISH, CMA, and prenatal/postnatal oncology workflows, with opportunities to review and interpret cases.
The candidate will participate in QA/QC, new method validation, and ongoing lab operations while adhering to policies and regulatory requirements.
Qualifications
- Bachelor's degree in biological sciences or a related field is required.
- ASCP CG eligible or certified is required for Senior level; eligibility for Intermediate level.
- Experience in cytogenetics and related testing methods preferred.
Responsibilities
- Perform and oversee cytogenetic testing including chromosome analysis, FISH, and CMA.
- Prepare digitized karyotype images and summarize findings.
- Contribute to QA/QC and validation of new testing methods.
- Review cases for accuracy and ensure appropriate test selection and interpretation.
- Assist with training and mentoring staff as needed.
Education
Tools
Job description
University of Colorado Anschutz
Department of Pathology
Cytogenetic Technologist (Healthcare Intermediate to Senior Professional)
Position #00818316 - Requisition #40768
The Colorado Genetics Laboratory (CGL), Department of Pathology, is seeking a full-time (1.0 FTE) technologist at the intermediate or senior level to join our clinical cytogenetics team. This position performs complex clinical cytogenomic testing utilizing standard and high-resolution chromosome analysis, fluorescence in situ hybridization (FISH) analysis, and chromosomal microarray analysis. Responsibilities also include specimen processing for prenatal diagnosis, postnatal constitutional genetic evaluation, and oncology testing to support cancer diagnosis and treatment monitoring.
In addition to performing testing, the technologist may review cases completed by other staff members for accuracy, completeness, and interpretation before Laboratory Director review, as appropriate for the position level. The technologist may also preview cases to ensure the requested testing is appropriate for the clinical indication and specimen received, support laboratory workflow and process decisions, and contribute to efficient laboratory operations.
The technologist participates in quality control and quality assurance activities, supports the development, validation, and implementation of new testing methodologies, and supports continuous improvement as cytogenomic technologies evolve. The successful candidate will adhere to established laboratory procedures, policies, and regulatory requirements while fostering a collaborative, efficient, and mission-driven work environment dedicated to providing high-quality patient care.
- Performs specimen processing for oncology chromosome analysis as the primary area of responsibility, including initiation, maintenance, and harvest of cell cultures and preparation of high-quality metaphase chromosome slides. May also perform specimen processing for fluorescence in situ hybridization (FISH) and chromosomal microarray (CMA) testing, including DNA extraction, as needed to support laboratory operations.
- Selects and performs appropriate specimen processing methodologies and techniques to produce high-quality cytogenetic and molecular preparations for clinical testing that meet established laboratory quality standards.
- Contributes to quality control, quality assurance, process improvement, and troubleshooting activities to maintain reliable laboratory operations. Recognizes and communicates processing errors, equipment malfunctions, or other issues affecting testing quality or workflow to senior technologists or laboratory leadership.
- Maintains proficiency in sterile technique, cell culture, DNA extraction, operation and maintenance of laboratory instrumentation, laboratory information systems, and the safe handling and disposal of biohazardous materials and hazardous chemicals in accordance with laboratory, institutional, and regulatory requirements.
- Participates in the validation, implementation, and optimization of new cytogenomic testing methodologies and laboratory procedures, as assigned.
- Performs oncology chromosome analysis and may also participate in constitutional chromosome analysis, fluorescence in situ hybridization (FISH) scoring, and chromosomal microarray analysis to support clinical diagnostic testing.
- Prepares high-quality digitized images of karyotypes and FISH specimens using computerized imaging systems and summarizes case findings by correlating chromosome, FISH, and chromosomal microarray findings.
- Prepares standardized case interpretations for reviewers and Laboratory Directors and participates in proficiency testing and other regulatory compliance activities required by accrediting agencies, including the College of American Pathologists (CAP).
- May review completed case analyses for accuracy, completeness, and adherence to laboratory standards prior to Laboratory Director review, as appropriate for the position level.
- May preview test requests and specimens to ensure appropriate test selection and support laboratory workflow and case prioritization.
- Prepares laboratory reagents and media, as needed, and monitors laboratory equipment quality control parameters to support reliable and compliant testing.
- Performs routine cleaning and preventive maintenance of laboratory equipment, disposes of hazardous waste in accordance with CGL and CU Anschutz policies and protocols, and maintains laboratory records and materials, including filing completed case slides.
- Maintains clean, organized, and well-stocked work areas; participates in inventory management; and may be authorized to purchase laboratory supplies using a CU procurement card and/or CU Marketplace in accordance with CU policies.
- Receives, labels, stores, and organizes laboratory supplies and independently manages laboratory resources to support efficient daily operations.
- Assists with the orientation and training of new employees, genetics students, residents, fellows, and other healthcare professionals in accessioning, wet laboratory processing, wet laboratory maintenance, inventory control, and established laboratory procedures to promote competency, consistency, and compliance with laboratory standards.
- Provides guidance and technical support to less experienced staff, as appropriate for the position level.
Onsite - this role is expected to work onsite and is located in Aurora, CO
Welcome to the Department of Pathology of the University of Colorado, Anschutz Medical Campus. The Department has grown substantially in the past 15 years, from 40 to 120 faculty in parallel with the remarkable growth of our hospital-based affiliates as well as the city and county of Denver. Our work is value driven and focused on scientific investigation, lifelong learning, and a balance of personal and professional values. In addition to a vibrant and highly competitive residency program with 25 positions, we offer 9 fellowships and participate in numerous graduate schools and the MD/PhD program of the CU School of Medicine.
We have AMAZING benefits and offerexceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:
- Medical: Multiple plan options
- Dental: Multiple plan options
- Additional Insurance: Disability, Life, Vision
- Retirement 401(a) Plan: Employer contributes 10% of your gross pay
- Paid Time Off: Accruals over the year
- Vacation Days: 22/year (maximum accrual 352 hours)
- Sick Days: 15/year (unlimited maximum accrual)
- Holiday Days: 15/year
- Tuition Benefit: Employees have access to this benefit on all CU campuses
- ECO Pass: Reduced rate RTD Bus and light rail service
There are many additional perks & programs with the CU Advantage.
Minimum Qualifications
- Bachelor's degree in biological science, nutrition, nursing, health, human services, psychology, counseling, social work, or a directly related field from an accredited institution and at least 1 year of cytogenetics experience
- American Society for Clinical Pathology (ASCP) - Clinical Cytogenetics (CG) eligible
- Bachelor's degree in biological science, nutrition, nursing, health, human services, psychology, counseling, social work, or a directly related field from an accredited institution.
- At least 2 years of cytogenetics experience, and ASCP Clinical Cytogenetics (CG) certification or equivalent qualification consistent with laboratory requirements.
Applicants must meet minimum qualifications at the time of hire.
Preferred Qualifications
- Experience working in a clinical cytogenetics laboratory.
- Experience with cell culture techniques.
- Experience processing and analyzing specimens for cancer chromosome analysis, chromosomal microarray, and/or fluorescence in situ hybridization (FISH) testing.
- Experience reviewing cytogenomic testing results.
- Experience supporting laboratory workflow and/or mentoring or training laboratory staff.
- Applicants must be legally authorized to work in the United States without requiring sponsorship. We are unable to provide work visa sponsorship or employment authorization for this position now or in the future.
- Ability to communicate effectively, both in writing and orally.
- Ability to establish and maintain effective working relationships with employees at all levels throughout the institution.
- Outstanding customer service skills.
- Ability to prioritize and manage multiple laboratory workflows in a high complexity clinical environment
- Knowledge of chromosome analysis, fluorescence in situ hybridization (FISH), and chromosomal microarray technologies and their clinical applications.
- Knowledge of the operation and routine maintenance of laboratory equipment and familiarity with medical and laboratory terminology.
- Proficiency with laboratory information systems and standard computer applications, including database, word processing, and spreadsheet software.
- Knowledge of HIPAA Privacy and Security Rules and College of American Pathologists (CAP) laboratory accreditation standards.
- Ability to maintain a high level of confidentiality and protect sensitive patient information in accordance with applicable policies and regulations.
- Demonstrated commitment to quality, accuracy, customer service, and attention to detail.
- Ability to organize, prioritize, and manage multiple responsibilities while meeting established deadlines.
- Demonstrated ability to communicate effectively, both verbally and in writing.
- Ability to establish and maintain effective working relationships with colleagues, healthcare professionals, and other stakeholders across the institution.
- Ability to work collaboratively in a team-oriented environment, adapt to changing priorities, and exercise sound judgment when seeking or providing assistance or guidance.
Applications will be accepted until finalists are identified, but preference will be given to complete applications received by August 30, 2026. Those who do not apply by this date may or may not be considered.
The starting salary range (or hiring range) for this position has been established as:
- Intermediate: $68,971 to $92,421
- Senior: $74,563 to $99,915
The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level.
Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.
Total Compensation Calculator
CU is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply, including protected veterans and individuals with disabilities.
The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@cuanschutz.edu.
The University of Colorado Anschutz is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.
CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program.
Application Materials Required: Cover Letter, Resume/CV, List of References
Job Category: Health Care
Primary Location: Aurora
Department: U0001 -- Anschutz Med Campus or Denver - 20112 - SOM-Pathology
Schedule: Full-time
Posting Date: Aug 10, 2026
Unposting Date: Ongoing
Posting Contact Name: Hala Nijmeh
Posting Contact Email: Hala.Nijmeh@cuanschutz.edu
Position Number: 00818316
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