Cyber Defense Platforms Staff Engineer

Alnylam Pharmaceuticals; Cambridge (MA); Hybrid; USD 174,000 - 236,000; Full time

Benefits offered by this job

Healthcare benefits

Annual incentive awards

Equity compensation

Job summary

Alnylam Pharmaceuticals seeks an Associate Director (Staff Engineer) for Cyber Defense Platforms in Cambridge, MA. You will own the defense technology stack end-to-end, including SIEM, SOAR, EDR, DLP, email security, and anti-phishing, with detection content, automation, and tooling driving enterprise-wide protection.

This senior IC role requires influencing across IT, security, and engineering teams, mentoring staff, and shaping platform roadmaps while delivering measurable improvements in

Qualifications

• 8+ years of progressive experience in security engineering, security operations, or detection engineering with ownership of defense platforms
• Deep hands-on expertise architecting SIEM, SOAR, EDR, or related protection technologies
• Strong software engineering skills in Python/Go/PowerShell for security automation
• Experience building and managing detection content at scale using MITRE ATT&CK
• Proven automation-driven improvements reducing response times or increasing capacity

Responsibilities

• Own deployment, configuration, and lifecycle of defense platforms (SIEM, SOAR, EDR, DLP, email security, phishing)
• Define platform roadmap; evaluate, deploy, integrate, and rationalize security technologies
• Engineer and maintain security data pipelines: onboarding, normalization, enrichment, retention, cost
• Own detection content lifecycle: development, testing, tuning, versioning, retirement
• Establish detection-as-code practices with CI/CD and automated validation
• Map coverage to MITRE ATT&CK; partner with threat intel, IR, and offensive security
• Design and build SOAR playbooks and workflow automation to speed triage
• Build internal tooling and APIs connecting security platforms to enterprise systems
• Set standards for defense technology; act as technical authority
• Lead cross-functional initiatives; mentor engineers and analysts

Skills

SIEM

SOAR

EDR

DLP

Email security

Anti-phishing

Python

Go

PowerShell

MITRE ATT&CK

Education

GIAC GCDA/GDAT/GCIA

CISSP

Tools

CI/CD pipelines

API development

Security automation tooling

Job description

Overview

As the Associate Director (Staff Engineer) for Cyber Defense Platforms, you will own the defense technology stack end-to-end: SIEM, SOAR, EDR, DLP, email security, and anti-phishing platforms, along with the detection content, automation, and tooling that make them effective. This is a senior individual contributor role with enterprise-wide impact: every alert triaged, threat detected, and incident contained across the company depends on the systems you build and operate.

This is a hybrid position and will be primarily based in Cambridge, MA.

Responsibilities

• Own the deployment, configuration, administration, and lifecycle of defense platforms including SIEM, SOAR, EDR, DLP, email security, and phishing
• Define the platform roadmap: evaluate, deploy, integrate, and rationalize security technologies to maximize defensive coverage and operational efficiency
• Engineer and maintain security data pipelines across the enterprise: log source onboarding, normalization, enrichment, retention, and cost management
• Own the detection content lifecycle end-to-end: development, testing, tuning, versioning, and retirement of rules and analytics across all platforms
• Establish detection-as-code practices, including version control, peer review, CI/CD deployment, and automated validation of content
• Map detection coverage to MITRE ATT&CK, identify gaps, and partner with threat intel, IR, and offensive security to convert findings into durable detections
• Design and build SOAR playbooks and workflow automation that reduce manual analyst effort and accelerate triage and response, including automated handling of user-reported phishing
• Build internal tooling, integrations, and APIs that connect security platforms to each other and to enterprise systems
• Set the standards for how Cyber Defense builds, deploys, and operates its technology, and serve as the technical authority for the defense technology domain
• Lead cross-functional technical initiatives across IT, infrastructure, and engineering teams, and mentor engineers and analysts across the broader team

Qualifications

• 8+ years of progressive experience in security engineering, security operations, or detection engineering, with demonstrated ownership of defense and security platforms
• Deep hands-on expertise architecting and administering: SIEM, SOAR, EDR, DLP, or email security and anti-phishing platforms
• Strong software engineering skills in a language commonly used for security automation (e.g., Python, Go, PowerShell), with experience building production-quality integrations and tooling
• Proven experience building and managing detection content at scale, measured against frameworks like MITRE ATT&CK
• Track record of delivering measurable operational improvements through automation, such as reduced response times or expanded capacity without added headcount
• Ability to operate autonomously in a build-from-zero environment and drive technical work across teams you don't manage
• Experience standing up or modernizing a security operations stack (SIEM migration, SOAR implementation, EDR rollout) from early maturity
• Cloud security experience, particularly AWS-native security services
• Experience in regulated industries (pharma, biotech, healthcare, financial services)
• Relevant certifications (e.g., GIAC GCDA/GDAT/GCIA, CISSP) or equivalent expertise

About Alnylam

We are the leader in RNAi therapeutics– a revolutionaryapproach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possibleand are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, wherean authentic, inclusive culture and breakthrough thinkingfuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.

Before applying, please review Alnylam's Candidate Privacy Notice regarding how Alnylam handles Personal Data you provide with your application for employment.

The pay range below reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well‑being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers

U.S. Pay Range

$174,300 - $235,700 USD