Cryo-EM Scientist

Brookhaven Science Associates, LLC; Upton (NY); On-site; USD 103,000 - 138,000; Full time

Benefits offered by this job

Comprehensive benefits program

Job summary

Brookhaven Science Associates, LLC seeks an experienced cryo-EM scientist to support operation and improvement of cryo-electron microscopy capabilities. The role includes operating and maintaining cryo-EM microscopes, training users, and developing new methods. Candidates should have a PhD in a relevant field and at least 2 years of postdoctoral experience.

The position offers a salary range of $103,000 - $138,000 per year with comprehensive benefits.

Qualifications

• PhD in a relevant field with at least 2 years of postdoctoral experience.
• Ability to work both independently and collaboratively.
• Flexibility in scheduling to support operations.

Responsibilities

• Operate and maintain cryo-EM microscopes and equipment.
• Train and support users through the training program.
• Optimize experiments and provide data collection guidance.

Skills

Effective communication

Organizational skills

Independent work

Data collection

Education

PhD in biology or related field

Tools

CryoSPARC

Relion

IMOD

Job description

Position Overview

The Laboratory for BioMolecular Structure (LBMS) at Brookhaven National Laboratory seeks an experienced scientist to support operation and improvement of LBMS cryo-electron microscopy (cryo-EM) capabilities. The cryo-EM scientist will help users obtain high-quality Cryo-EM data, lead cryo-EM efforts on collaboration projects, participate in the 3-tier training program, and develop or implement new methods. A strong background in biology and experience with cryo-EM techniques are essential.

Responsibilities

• Operate and maintain cryo-EM microscopes and related equipment, including sample preparation and image acquisition.
• Train, support, and educate users and the public through the 3-tier training program.
• Collaborate with users to design and optimize experiments; provide guidance on sample preparation, data collection, and analysis.
• Communicate with academic and industrial user communities and provide support.
• Contribute to method development in cryo-EM and support overall LBMS operations.

Qualifications

• PhD in a relevant field (biology, biochemistry, biophysics, chemistry, microbiology, virology) with at least 2 years of postdoctoral experience.
• Effective, constructive communicator.
• Ability to work independently as a self-starter and as a proactive team player.
• Ability to maintain a flexible schedule, including evenings and weekends, to support continuous facility operations and user needs.
• Strong organizational and record-keeping skills.
• Experience in at least one of the following areas: cryo-EM instrumentation, sample preparation, high-resolution single-particle data collection, or cryo-electron tomography.

Preferred Qualifications

• Experience with single-particle image processing software such as CryoSPARC, Relion, cisTEM, or EMAN2.
• Experience with tomography image processing software such as IMOD, AreTomo, or related packages.
• Experience with cryogenic sample preparation using cryo-FIB or cryo-microtome.
• Experience with fluorescence light microscopy for correlative or complementary studies.
• Experience working in a Linux/UNIX environment.
• Strong record of peer-reviewed publications.

Compensation and Benefits

Salary range: $103,000 - $138,000 per year. The position offers a comprehensive benefits program designed to support employee well-being and career development.

Equal Opportunity Statement

Brookhaven National Laboratory is an Equal Employment Opportunity Employer. We consider all qualified applicants without regard to any characteristic protected by law. Individuals with disabilities are provided reasonable accommodation to participate in the application and interview process, perform essential job functions, and receive other employment benefits. Please contact us to request accommodation.