Corporate Facilities & Engineering Senior Manager (Remote Global Reliability Network Lead)

Amgen Inc. (IR); Puerto Rico; Hybrid; USD 140,000 - 210,000; Full time

Job summary

Amgen is seeking an Engineering Sr. Manager to lead the Global Reliability Network within Engineering Operations Services.

You will guide a network of site reliability engineers and maintenance leaders to turn data into actionable improvements that boost asset reliability and availability. Responsibilities include strategy development, KPI sharing, governance representation, and deploying PM/PdM optimizations while standardizing criticality-based maintenance across sites.

Qualifications

• Doctorate degree or 2+ years of engineering industry experience, or Master’s with 4+ years, or Bachelor’s with 6+ years, or Associate’s with 10+ years, or High school diploma/GED with 12 years in engineering.
• Beyond that, additional preferred qualifications are:
• Fluent English, written and verbal.

Responsibilities

• Lead the Global Reliability Network with site reliability engineers, maintenance leaders, system owners, and SMEs.
• Develop and execute the Reliability Network strategy, goals and milestones.
• Share reliability KPIs, bad actor trends, equipment improvements and lessons learned.
• Represent reliability priorities in senior engineering governance forums.
• Convert reliability insights into corrective actions, PM/PdM optimization and capital recommendations.
• Define a standard risk-based asset criticality approach across sites and standardize maintenance strategies.
• Lead Asset Performance Monitoring and PlantPulse adoption with SAP EAM and other teams.
• Translate reliability improvements into business impact and capacity gains.

Skills

CMMS/EAM

Asset performance monitoring

Power BI

Cross-functional leadership

GMP/biopharma

ISO 55000

FMEA/FMECA

Predictive maintenance

PdM

English fluency

Education

Doctorate degree

Master’s degree

Bachelor’s degree

Associate’s degree

High school diploma/GED

Tools

SAP

Maximo

SAP Analytics Cloud

Job description

Career Category Engineering Job Description Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

What you will do

In this vital role, you will lead Amgen’s Global Reliability Network as part of Engineering Operations Services (EOS) department, helping sites turn reliability data, maintenance history, failure trends, and equipment performance insights into actions that improve asset reliability, equipment availability, maintenance effectiveness, and operational capacity. You will also serve as the business lead for the CMMS Asset Performance Monitoring module and reliability-focused equipment insight tools across Amgen’s manufacturing network. Occasional on-site presence at the nearest Amgen operation site may be requested based on business needs.

• Lead the Global Reliability Network Lead a network of site reliability engineers, maintenance leaders, system owners, and technical SMEs.
• Develop and execute the Reliability Network strategy, goals, milestones, and maturity plans.
• Share reliability KPIs, bad actor trends, equipment improvements, lessons learned, and reusable solutions.
• Represent reliability priorities and recommendations in senior engineering governance forums.
• Turn data insights into equipment improvements Use CMMS data, Asset Performance Monitoring, Plant Pulse, PdM findings, and site input to identify recurring failures, high-risk assets, downtime drivers, and bad actors. Convert reliability insights into corrective actions, equipment improvements, PM/PdM optimization, spare parts strategies, and capital recommendations. Track improvement actions, verify benefits, and scale successful practices across sites.
• Advance asset criticality and maintenance strategy Define and maintain a standard risk-based asset criticality approach across sites. Use criticality to prioritize maintenance strategies, work execution, spare parts, lifecycle planning, and performance monitoring. Standardize maintenance strategies based on criticality, failure modes, operating context, and performance history. Support RCM, FMEA/FMECA, PM optimization, predictive maintenance, and condition-based maintenance approaches.
• Lead Asset Performance Monitoring and PlantPulse adoption Define business requirements for asset health, criticality, failure modes, risk ranking, performance monitoring, and continuous improvement. Partner with SAP EAM, Technology/IS, site engineering teams, the Reliability Network, and SMEs to support deployment, training, adoption, and data quality. Serve as PlantPulse business owner to ensure tools address reliability pain points, support troubleshooting, and generate actionable equipment insights.
• Connect reliability to business value Partner with OPEX teams to identify reliability improvements that unlock capacity and reduce downtime. Translate recurring failures and reliability constraints into business impact. Support lifecycle risk visibility for critical assets, including deterioration, obsolescence, maintenance cost, reliability concerns, and end-of-life planning. Integrate reliability principles into capital projects from conceptual design through turnover.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The Engineering Sr. Manager professional we seek is a collaborative individual contributor leader with these qualifications.

Basic Qualifications:

• Doctorate degree & 2 years of engineering industry experience OR Master’s degree & 4 years of engineering industry experience OR Bachelor’s degree & 6 years of engineering industry experience OR Associate’s degree & 10 years of engineering industry experience OR High school diploma/GED & 12 years of engineering industry experience

Beyond that, additional preferred qualifications are:

• Bachelor’s degree in Engineering.
• Experience in maintenance, reliability, engineering, asset management, manufacturing operations, and/or engineering digital transformation.
• Experience leading cross-functional initiatives in site, multi-site, or global environments.
• Strong knowledge of CMMS/EAM and asset performance monitoring systems, such as SAP, Maximo, or equivalent.
• Working knowledge of asset criticality, RCM, FMEA/FMECA, RCA, PM optimization, PdM, condition-based maintenance, and reliability KPIs.
• Ability to translate site needs into scalable business processes, digital product requirements, and improvement actions.
• Strong stakeholder management, communication, network leadership, and change leadership skills.
• Experience with analytics or dashboarding tools such as Power BI, Spotfire, SAP Analytics Cloud, or equivalent.
• Experience in GMP, biopharmaceutical manufacturing, GxP research, laboratory, or other regulated operations.
• Familiarity with ISO 55000, ISO 14224, SMRP, Uptime Elements, or similar reliability and asset management frameworks.
• Certification such as CMRP, CRL, PMP, Lean Six Sigma, or asset management certification.
• Experience deploying predictive maintenance, condition monitoring, smart sensors, AI-enabled analytics, or advanced asset health technologies.
• Experience developing business cases for reliability, maintenance, lifecycle asset management, or capacity improvement projects.
• Fluent English proficiency, written and verbal.
• Availability to commute to the nearest Amgen operation site as business needs arise, including for meetings, training, operational support, or other business-critical activities.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

• - A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental & vision coverage, and life & disability insurance
• - A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• - Stock-based long-term incentives
• - Award-winning time-off plans
• - Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Sponsorship

Sponsorship for this role is not guaranteed.

Equal Opportunity

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.

Amgen is committed to unlocking the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. This approach begins by using tools like advanced human genetics to unravel the complexities of disease and understand the fundamentals of human biology. Amgen focuses on areas of high unmet medical need and leverages its biologics manufacturing expertise to strive for solutions that improve health outcomes and dramatically improve people's lives. A biotechnology pioneer since 1980, Amgen has grown to be one of the world's leading independent biotechnology companies, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential. For more information, visit www.amgen.com and follow us on www.twitter.com/amgen