Contractor, Drug Metabolism and Pharmacokinetics (DMPK)

PTC Therapeutics, Inc; Bridgewater (MA); On-site; USD 62,000 - 96,000; Full time

Job summary

PTC Therapeutics, Inc. is seeking a Contractor in DMPK to plan and perform in vitro and in vivo metabolism/bioanalysis assays in support of discovery and early development.

You will interpret data and communicate results to the supervisor and colleagues as part of cross-functional project teams. The position requires a Master’s or Bachelor's in related sciences with 2–4 years of relevant experience in pharma/biotech, and offers an hourly pay range with up to 5% travel.

Qualifications

• Master's or Bachelor's degree in listed sciences with required years of experience.
• Experience in pharmaceutical/biotech environment preferred.
• Knowledge of drug metabolism and pharmacokinetics required.

Responsibilities

• Initiates and executes scientific research within a multi-disciplinary team.
• Performs in vitro and in vivo metabolism/bioanalysis assays.
• Develops new DMPK assays and improves existing ones.
• Documents results and prepares study reports.
• Contributes to lab maintenance and equipment purchases.

Skills

DMPK knowledge

LC-MS/MS experience

Team collaboration

Education

Master's degree in Biology, Chemistry, Biochemistry, Pharmaceutical Science, Pharmacology or related field

Bachelor's degree in Biology, Chemistry, Biochemistry, Pharmaceutical Science, Pharmacology or related field

Tools

LC-MS/MS instrumentation

Laboratory equipment & maintenance

Job description

PTC Therapeutics is a global commercial biopharmaceutical company. For over 25 years our team has been deeply committed to a unified purpose: Extending life's moments for children and adults living with a rare disease.

At PTC, we cultivate an inclusive culture where everyone feels valued, respected, and empowered. We welcome candidates from all backgrounds to join our team, fostering a strong sense of belonging.

Visit our website to learn more about our company and culture! Site: www.ptcbio.com

Job Description Summary:

The Contractor, Drug Metabolism and Pharmacokinetics (DMPK) plans and performs in vitro and in vivo metabolism/bioanalysis assays in support of DMPK studies in discovery and early development.

The Contractor, DMPK interprets data and communicates experimental results to his/her supervisor and colleagues.

The incumbent works cross-functionally with internal departments, and external resources as appropriate, as part of PTC's discovery science project teams.

The Contractor, DMPK supports adherence to relevant regulatory requirements and company Standard Operating Procedures (SOPs) as appropriate.

ESSENTIAL FUNCTIONS

Primary duties/responsibilities:

• With guidance, initiates and executes scientific research and experiments and interprets and communicates results as part of multi-disciplinary team(s).
• Performs and maintains established in vitro and in vivo metabolism/bioanalysis assays.
• With guidance, develops new, and improves upon existing DMPK assays.
• Performs hands‑on in vitro and in vivo metabolism/bioanalysis assays using LC-MS/MS.
• Documents experiment details in lab books, records results in database and prepares study reports.
• Abides by all safety and regulatory guidelines.
• Performs other tasks and assignments as needed or specified by management.
• Contributes to general lab needs such as:
• Equipment maintenance and/or troubleshooting.
• Capital equipment purchases.

KNOWLEDGE/SKILLS/ABILITIES REQUIRED

* Minimum level of education and years of relevant work experience.

* Special knowledge or skills needed and/or licenses or certificates required.

• A Master's degree in Biology, Chemistry, Biochemistry, Pharmaceutical Science, Pharmacology or other related scientific discipline and a minimum of 2 years of relevant and progressively responsible experience in a pharmaceutical, biotechnology or similar environment OR a Bachelor's degree in these same disciplines and a minimum of 4 years of the same experience.

*Special knowledge or skills and/or licenses or certificates preferred.

• Knowledge of drug metabolism and pharmacokinetics in discovery preclinical research.

*Travel requirements

• Up to 5%
• Office/Laboratory based position

Expected Hourly Range:

$45-$70/hour. The hourly salary offered will be contingent on assessment of candidate education level, background, and experience relative to the requirements of the position they are being considered for, as well as review of internal equity.

EEO Statement:

PTC Therapeutics is an equal opportunity employer. We welcome applications from all individuals, regardless of race, color, national origin, gender, age, physical characteristics, social origin, disability, religion, family status, pregnancy, sexual orientation, gender identity, gender expression, disability, veteran status or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.