Computational Biologist, Perturb-seq & Microglia

Artists Raising Consciousness, Inc.; Palo Alto (CA); On-site; USD 150,000 - 190,000; Full time

Job summary

Arc Institute is hiring two Scientist positions in Palo Alto to turn large-scale Perturb-seq, single-cell, and multi-omic datasets into mechanistic biological insights. Scientists will work at the Computational Technology Center, collaborating with experimental teams and ML researchers to identify functional relationships between genes and cell states.

Successful candidates will model and interpret high-throughput data, contribute to the Virtual Cell and Alzheimer's Disease Initiatives, and help

Qualifications

• PhD in computational biology, bioinformatics, genomics, systems biology, ML, CS, or related field.
• Postdoc experience is 0–4 years.
• Strong background in large-scale genomic data analysis and modeling.

Responsibilities

• Perform tertiary analyses of Perturb-seq, single-cell sequencing, multi-omic data to link genes to cellular phenotypes.
• Model perturbation effects and trajectories in cell states across experiments.
• Collaborate with experimental teams to refine study design and interpretation.
• Develop and share reusable analysis notebooks and software tools.
• Present results to Arc researchers and contribute to open-source projects when relevant.

Skills

Single-cell data analysis

Perturbational data analysis

Education

PhD in computational biology, bioinformatics, genomics, systems biology, machine learning, computer science, molecular biology

Job description

Arc Institute is hiring two Scientist positions in Palo Alto to turn large-scale Perturb-seq, single-cell, and multi-omic datasets into mechanistic biological insights. Scientists will work at the Computational Technology Center, collaborating with experimental teams and ML researchers to identify functional relationships between genes and cell states.

Successful candidates will model and interpret high-throughput data, contribute to the Virtual Cell and Alzheimer's Disease Initiatives, and help