Computational Biologist

Biohub; Chicago (IL); On-site; USD 130,000 - 163,000; Full time

Benefits offered by this job

Generous employer match on 401(k) contributions

Paid time off for volunteering

Relocation support

Job summary

Biohub in Chicago is seeking an exceptional Computational Biologist for spatiotemporal multi-omics technology. Candidates should possess a PhD in bioinformatics or a related field and have experience in developing bioinformatic methods and analysis pipelines.

This hybrid position requires collaboration with experimental scientists and development of data workflows and visualization tools. The role offers a competitive salary and engaging work culture focused on innovation.

Qualifications

• PhD in bioinformatics, computer science, statistics, or a related quantitative discipline.
• Minimum 2 years of experience in developing bioinformatic methods or software tools.
• Minimum of 1 year of experience in spatial data analysis or multi-omics integration.

Responsibilities

• Develop data analysis workflows for spatiotemporal and multi-omics datasets.
• Build visualization tools for complex biological data.
• Integrate proteomics, metabolomics, and related datasets.

Skills

Bioinformatics methods development

Spatial data analysis

Machine learning for biological applications

Collaboration with wet-lab teams

Education

PhD in bioinformatics or related field

Tools

Programming languages (for bioinformatics)

Job description

Biohub is the first large‑scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general‑purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere.

The Team

The Biohub is a group of nonprofit research institutes that bring together scientists, engineers, and physicians with the goal of pursuing grand scientific challenges on 10- to 15-year time horizons. The Biohub focuses on understanding underlying mechanisms of disease and developing new technologies that will lead to actionable diagnostics and effective therapies.

Our Vision

• We pursue large scientific challenges that cannot be pursued in conventional environments
• We enable individual investigators to pursue their riskiest and most innovative ideas
• The technologies developed at the Biohub facilitate research by scientists and clinicians at our home institutions and beyond
• Diversity of thought, ideas, and perspectives are at the heart of Biohub and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution.

The Opportunity

The Biohub Chicago is seeking an exceptional Computational Biologist, Spatiotemporal Multi‑Omics to join our growing team. We are looking for a creative and collaborative bioinformatics researcher who is excited to build the analytical foundation for our spatiotemporal multi‑omics technology platform.

What You’ll Do

• Develop data analysis workflows for spatiotemporal and multi‑omics datasets.
• Build visualization tools that enable exploration and interpretation of complex biological data across space and time.
• Integrate proteomics, metabolomics, and related datasets, and explore machine learning or transfer learning approaches to support biological discovery.
• Collaborate closely with experimental scientists, communicate findings clearly, and contribute to publications, presentations, and open‑source software as appropriate.

What You’ll Bring

• PhD in bioinformatics, computer science, statistics, computational biology, biomedical engineering or a related quantitative discipline.
• Minimum 2 years of experience in developing bioinformatic methods, analysis pipelines, or software tools for biological data using appropriate programming language.
• Minimum of 1 year of experience in at least one of the following areas: spatial data analysis, multi‑omics integration, or machine learning for biological applications.
• A strong record of research productivity, including publications, open‑source contributions, or both.
• A collaborative mindset, strong communication skills, and enthusiasm for working closely with wet‑lab teams.

Preferred Qualifications

• 1+ year of experience with imaging mass spec (e.g., MALDI)
• 1+ year of experience with single‑cell proteomics and/or metabolomics
• 1+ year of experience building visualization tools, or scientific software.

Compensation

The Chicago, IL base pay range for a new hire in this role is $130,000 - $163,000. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job‑related skills and experience, as evaluated throughout the interview process.

This position may be eligible to participate in our discretionary annual performance bonus program. Bonus eligibility and targets are determined in accordance with our total rewards philosophy and may vary by role.

Better Together

As we grow, we’re excited to strengthen in‑person connections and cultivate a collaborative, team‑oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in‑office days determined by the team’s manager. The exact schedule will be at the hiring manager's discretion and communicated during the interview process.

Benefits for the Whole You

We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.

• Provides a generous employer match on employee 401(k) contributions to support planning for the future.
• Paid time off to volunteer at an organization of your choice.
• Relocation support for employees who need assistance moving

As set forth in the organization’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.