Computational Associate

Massachusetts General Hospital; Boston (MA); On-site; USD 70,000 - 95,000; Full time

Job summary

Massachusetts General Hospital is seeking a Computational Research Associate to join an interdisciplinary research team focused on precision oncology through digital pathology, AI, machine learning, genomics, and multi-omics research. You will work with clinicians and researchers at Mass General Hospital and Harvard Medical School.

You will develop ML and CV models, analyze multi-omics data, and build workflows that link pathology images to molecular and clinical outcomes, contributing to

Qualifications

• Bachelor's or Master's degree in Computer Science, Bioinformatics, Computational Biology, Biomedical Engineering, Statistics, Data Science, Genetics, Epidemiology, or related field.
• Proficiency in Python and/or R programming.
• Experience with machine learning, artificial intelligence, bioinformatics, computational biology, or biomedical data science.
• Strong analytical, organizational, communication, and collaboration skills.
• Experience with digital pathology, whole-slide image analysis, computer vision, or medical imaging applications.
• Familiarity with PyTorch or TensorFlow.
• Experience analyzing genomics, RNA sequencing, spatial transcriptomics, single-cell, or epigenomic datasets.
• Experience integrating and interpreting multiple biological data modalities across complex research projects.

Responsibilities

• Develop and apply machine learning and computer vision models for digital pathology and whole-slide image analysis.
• Analyze genomic, transcriptomic, epigenomic, and spatial biology datasets.
• Build computational workflows that integrate pathology images, molecular data, and clinical outcomes.
• Support biomarker discovery and prognostic model development through multimodal data analysis.
• Collaborate with a multidisciplinary team and contribute to scientific presentations, manuscripts, and publications.

Skills

Python

R programming

Machine learning

Statistical analysis

Communication

Education

Bachelor's or Master's degree in Computer Science

Bioinformatics / Computational Biology / Biomedical Engineering / Statistics

Related quantitative field

Tools

PyTorch

TensorFlow

Job description

Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Site: The General Hospital Corporation

Job Summary

Summary: The Research Data Analyst will work under the direction of the Principal Investigator to assist graduate students, post-doctoral fellows, clinical fellows, and others with research projects that focus on analytical and computational needs.

Essential Functions

• Provide direct assistance with experimental studies.
• Performs basic computational modeling and statistical analysis; prepares drafts of work for review; applies feedback received to create final analyses and/or reports.
• Meets with the PI and team to discuss work plans, activities, and results to support the applicability of efforts, learning opportunities, and professional development.
• Reviews, collates, and prepares standard analyses of medical record data.
• Perform administrative tasks, such as required for data collection; prepare documentation and record-keeping; update databases; run reports.
• Conducts literature searches and submits appropriate articles to PI and team for consideration; identifies topics of interest for personal reading and may present at lab meetings.

Qualifications

Joint Urology-Pathology Research Laboratory | Massachusetts General Hospital & Harvard Medical School

Drs. Chin-Lee Wu and Douglas Dahl are seeking a Computational Research Associate to join an interdisciplinary research team focused on advancing precision oncology through digital pathology, artificial intelligence, machine learning, genomics, and multi-omics research in genitourinary cancers.

This is an exciting opportunity to contribute to cutting-edge translational research at the intersection of computational pathology, cancer biology, human genetics, and biomedical data science while collaborating with pathologists, clinicians, and researchers at Massachusetts General Hospital and Harvard Medical School.

Key Responsibilities

• Develop and apply machine learning and computer vision models for digital pathology and whole-slide image analysis.
• Analyze genomic, transcriptomic, epigenomic, and spatial biology datasets.
• Build computational workflows that integrate pathology images, molecular data, and clinical outcomes.
• Support biomarker discovery and prognostic model development through multimodal data analysis.
• Collaborate with a multidisciplinary team and contribute to scientific presentations, manuscripts, and publications.

Preferred Qualifications

• Bachelor's or Master's degree in Computer Science, Bioinformatics, Computational Biology, Biomedical Engineering, Statistics, Data Science, Genetics, Epidemiology, or a related quantitative field
• Proficiency in Python and/or R programming
• Experience with or strong interest in machine learning, artificial intelligence, bioinformatics, computational biology, or biomedical data science
• Strong analytical, organizational, communication, and collaboration skills
• Experience with digital pathology, whole-slide image analysis, computer vision, or medical imaging applications
• Familiarity with deep learning frameworks such as PyTorch or TensorFlow
• Experience analyzing genomics, RNA sequencing, spatial transcriptomics, single-cell, or epigenomic datasets
• Experience integrating and interpreting multiple biological data modalities across complex research projects

Why Join Us?

• Work on innovative research combining AI, digital pathology, genomics, and precision medicine.
• Collaborate with world-class investigators at Massachusetts General Hospital and Harvard Medical School.
• Gain hands-on experience with advanced computational and translational research methodologies.
• Receive mentorship and opportunities for scientific authorship, presentations, and career development.
• Contribute to discoveries that improve the understanding and treatment of cancer.

Education

Bachelor's Degree Computational Biology required or Bachelor's Degree Related Field of Study required

Experience

Experience as attained through education 0-1 year required

Knowledge, Skills and Abilities

• Understanding of human pathophysiology, hematologic function, pregnancy physiology and related fields of study.
• Understanding of mathematical modeling, including dynamical systems, statistical analysis, and computational methods.
• Ability to work collaboratively as part of a team and with supervision from team members.
• Ability to work productively with scientists and clinicians at all levels.
• Works in an organized manner with the ability to follow instructions, processes and timelines.
• Can identify roadblocks occurring within areas of responsibility and refer them to