Clinical Science Lead

Takeda; Boston (MA); On-site; USD 177,000 - 278,000; Full time

Job summary

Takeda is seeking a Director-level leader to shape the scientific and operational strategy for clinical studies across interventional and non-interventional programs. You will drive Phase 3B/Phase 4 efforts, real-world evidence, and investigator-initiated activities, ensuring quality, compliance, and alignment with business priorities in a digitally enabled environment.

You will collaborate across functions to govern studies, oversee vendors, manage budgets, and translate complex findings into

Qualifications

• Advanced degree in a scientific, clinical, epidemiologic, quantitative, or health-related discipline.
• 10+ years of experience in clinical development, evidence generation, clinical research, or related disciplines involving interventional and non-interventional studies.
• Significant experience in clinical science, clinical development, study implementation, epidemiology, real-world evidence, or related biopharmaceutical functions.
• Strong experience authoring, reviewing, and approving clinical trial protocols and related study documentation.
• Experience leading global or multi-country clinical studies through implementation and publication.

Responsibilities

• Provide scientific and operational leadership for planning, implementation, oversight, execution, and reporting of clinical, real-world evidence, and externally sponsored studies.
• Lead study design and document development through protocols, amendments, study concepts, and related materials.
• Ensure study quality and feasibility by aligning study designs and execution plans with evidence generation priorities and stakeholder needs.
• Manage study delivery and performance by overseeing timelines, enrollment, budgets, operational metrics, risks, and quality indicators.
• Interpret and communicate clinical findings by translating complex clinical and safety data into recommendations, reports, publications, and decision-support materials.
• Partner across functional teams to support compliant study governance, vendor oversight, contracting, reporting, and archiving activities.
• Lead vendor and external partnership management while maintaining budget stewardship across the assigned portfolio.
• Drive continuous improvement and innovation through the adoption of digital and AI-enabled tools that strengthen planning, oversight, analytics, and decision-making.

Skills

Leadership & strategy

Clinical development

Evidence generation

Regulatory compliance

Cross-functional collaboration

Education

Advanced degree in a scientific/clinical discipline

Job description

Job Description

About the Role:

In this Director level role, you will help shape the scientific and operational strategy for clinical studies across a diverse evidence generation portfolio. You will play a key role in advancing Phase 3B and Phase 4 interventional and non-interventional studies, real-world evidence initiatives, collaborative research, and investigator-initiated activities. Working across functions, you will help ensure studies are scientifically robust, operationally feasible, and delivered with a strong focus on quality, compliance, and business priorities. You will be part of a team that supports evidence-based decision-making while advancing efficient, scalable, and digitally enabled approaches to clinical research. Your work will contribute to the successful design, implementation, governance, and delivery of studies that generate meaningful evidence and support organizational goals, while promoting the appropriate use of digital and artificial intelligence-enabled tools to strengthen planning, oversight, analytics, and decision-making.

How You Will Contribute:

• Provide scientific and operational leadership for the planning, implementation, oversight, execution, and reporting of clinical, real-world evidence, and externally sponsored studies.

• Lead study design and document development through the creation, review, and approval of protocols, amendments, study concepts, and related materials.

• Ensure study quality and feasibility by aligning study designs and execution plans with evidence generation priorities and stakeholder needs.

• Manage study delivery and performance by overseeing timelines, enrollment, budgets, operational metrics, risks, and quality indicators.

• Interpret and communicate clinical findings by translating complex clinical and safety data into recommendations, reports, publications, and decision-support materials.

• Partner across functional teams to support compliant study governance, vendor oversight, contracting, reporting, and archiving activities.

• Lead vendor and external partnership management while maintaining budget stewardship across the assigned portfolio.

• Drive continuous improvement and innovation through the adoption of digital and artificial intelligence-enabled tools that enhance evidence generation and study management.

Qualifications:

• Advanced degree in a scientific, clinical, epidemiologic, quantitative, or health-related discipline.

• 10+ years of experience in clinical development, evidence generation, clinical research, or related disciplines involving interventional and non-interventional studies.

• Significant experience in clinical science, clinical development, study implementation, epidemiology, real-world evidence, or related biopharmaceutical functions.

• Strong experience authoring, reviewing, and approving clinical trial protocols and related study documentation.

• Experience leading global or multi-country clinical studies through implementation and publication.

• Extensive knowledge of interventional and non-interventional study designs, good clinical practice, applicable regulations, ethics, quality standards, and standard operating procedure-driven practices.

• Demonstrated ability to interpret complex clinical and safety data and communicate findings effectively to diverse audiences.

• Strong program leadership, stakeholder management, vendor oversight, decision-making, and team leadership skills, including experience using digital and artificial intelligence-enabled tools in a regulated environment.

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:

Boston, MA

U.S. Base Salary Range:

$177,000.00 - $278,080.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time

Job Exempt

YesIt is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.