Clinical Research Program Manager, Oncology Operations (Academic Medical Center)

Cedars-Sinai; Los Angeles (CA); On-site; USD 90,000 - 120,000; Full time

Job summary

A leading medical institution in Los Angeles is seeking a Clinical Research Program Manager to lead oncology clinical trials. The successful candidate will provide operational leadership, ensuring compliance with regulatory standards while mentoring research staff. Requirements include at least 5 years of management experience and 3 years in clinical research, specifically in oncology. This role will significantly impact the advancement of cancer therapies and improve patient outcomes.

Qualifications

• Minimum 5 years of experience in management or related field.
• Minimum 3 years of experience in a clinical research or related industry.
• Demonstrated oncology and/or cancer clinical research experience.

Responsibilities

• Provide strategic and operational leadership across oncology clinical trials.
• Drive program governance ensuring compliance with regulatory standards.
• Establish and improve operational workflows and quality standards.

Skills

Oncology clinical research management

Regulatory compliance (FDA, IRB, GCP)

Operational leadership

Critical decision making

Team mentoring

Communication skills

Education

High School Diploma or GED

Job description

This is a unique opportunity for an experienced Clinical Research Program Manager with a strong background in oncology research and academic medical centers to lead complex, high-impact clinical trial programs at the forefront of innovation.

In this role, you won’t just manage operations—you will shape the direction and execution of a dynamic oncology research portfolio, partnering closely with physician-scientists, cross-functional leaders, and institutional stakeholders. Your expertise in clinical research operations, including regulatory compliance (FDA, IRB, GCP), study coordination, and staff development, will directly influence the advancement of novel therapies and improve outcomes for patients facing cancer

We are seeking a leader who understands the rigor and pace of academic research environments and brings a deep commitment to scientific integrity, operational excellence, and patient-centered outcomes.

What You’ll Do:

• Provide strategic and operational leadership across a portfolio of oncology clinical trials within an academic medical setting.
• Drive program governance, ensuring compliance with regulatory standards (FDA, IRB, GCP) while maintaining efficiency and quality.
• Serve as a trusted partner to Principal Investigators and senior leadership, advising on program strategy, feasibility, and execution.
• Establish and continuously improve operational workflows, metrics, and quality standards across studies.
• Lead, mentor, and develop research staff while fostering a culture of accountability, collaboration, and innovation.
• Independently make critical decisions impacting program operations, timelines, and resource allocation.

What Sets You Apart

• Proven experience managing oncology clinical research programs within an academic medical center.
• Strong understanding of complex clinical trial design, regulatory frameworks, and research infrastructure.
• Ability to operate both strategically and tactically in a fast-paced, high-stakes environment
• Confident communicator with the ability to influence across multidisciplinary teams
• Passion for advancing cancer research and improving patient outcomes.
• High School Diploma or GED required
• Minimum 5 years of experience in management, program/project management, or a related field.
• Minimum 3 years of experience in a clinical research or related industry setting
• Demonstrated oncology and/or cancer clinical research experience required
• Academic medical center or academic research institution experience required
• Demonstrated experience managing and directly supervising staff within a clinical research environment.