Clinical Research Physician

Eli Lilly; Boston (MA); On-site; USD 250,000 - 350,000; Full time

Job summary

Verve Therapeutics, a Lilly subsidiary, seeks a Senior Medical Director, Clinical Development to lead clinical trial oversight for gene-editing therapies targeting cardiovascular disease.

The role requires medical leadership, regulatory expertise, and collaboration across cross-functional teams to ensure patient safety and scientific integrity throughout trial lifecycles.

Qualifications

• Medical Doctor must be board eligible or certified in a medical specialty relevant to the role or have completed the comparable level of post-medical school clinical training relevant to the country of hiring. U.S. trained.
• Experience leading clinical development programs and regulatory submissions is required.
• Strong communication, leadership, and attention to detail are essential.

Responsibilities

• Provide medical oversight and leadership across the clinical trial lifecycle.
• Lead preparation of key clinical documents (study protocols, investigators' brochures, informed consent).
• Ensure development strategy aligns with regulatory guidelines and cross-functional input.
• Lead review of trial data including safety and efficacy endpoints.
• Represent the company at regulatory discussions, conferences, and advisory boards.
• Collaborate with operations, regulatory, and data teams to execute trials on time.

Skills

Medical leadership

Regulatory strategy

Cross-functional collaboration

Clinical development

IND submissions

Education

MD/DO

Board eligible/certified

Job description

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work—but it’s work worth doing. If you’re driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.

Verve Therapeutics – a wholly ownedsubsidiaryof Eli Lilly and Company – is seeking a Senior Medical Director, Clinical Development to lead the clinical trial efforts for our innovative gene editing therapies targeting cardiovascular disease. In this key role, you will provide medical oversight and strategic leadership throughout the trial lifecycle, ensuring scientific integrity, regulatory compliance, and patient safety. You will collaborate with cross-functional teams, contribute to regulatory submissions, and help implement biomarker strategies. You will help shape the transition of assets from Phase 1 to later phases of development. Reporting to the Vice President of Genomic Medicine, this high-visibility position offers the opportunity to drive clinical development and engage with key external stakeholders. The ideal candidate will excel in a fast-paced, dynamic environment and possess strong communication skills and attention to detail.

Job Responsibilities

• Provide medical oversight and strategic leadership throughout the clinical trial lifecycle, including the design, planning, execution, and interpretation of trials for investigational compounds, ensuring patient safety and scientific integrity.
• Contribute to the design and development of key clinical documents, including study protocols, investigator’s brochures, informed consent documents, and other essential materials.
• Ensure the clinical development strategy adheres to industry best practices and regulatory guidelines while collaborating with study investigators and medical experts in the development and execution of study protocols.
• Lead the review and interpretation of clinical trial data, including safety assessments, efficacy endpoints, and overall trial progress.
• Serve as a key medical expert in cross-functional discussions, including regulatory submissions, investigator meetings, and advisory boards.
• Work with the Clinical Operations team to identify and resolve trial-related issues, ensuring smooth execution and compliance.
• Collaborate closely with the clinical operations, regulatory, and data management teams to ensure timely and high-quality execution of clinical trials.
• Collaborate with the research team to develop and implement a translational biomarker strategy for the program integrating early-phase data to inform clinical strategy.
• Contribute to regulatory submission efforts by providing clinical insight into IND submissions, clinical trial applications, and other regulatory documents support responses to health authorities and ethics committees.
• Represent the company at scientific conferences, advisory boards, and meetings with regulatory authorities.
• Develop and maintain relationships with external stakeholders, including key opinion leaders (KOLs), clinical investigators, and contract research organizations (CROs).
• Foster a collaborative and positive team environment that encourages innovation, scientific rigor, and high-performance standards.
• Travel to clinical sites, conferences, and regulatory meetings as needed.
• Other duties as assigned.

Qualifications:

• Minimum Requirements

  • Medical Doctor must be board eligible or certified in a medical specialty relevant to the role or have completed the comparable level of post-medical school clinical training relevant to the country of hiring. U.S. trained