Clinical Research Nurse - 258533

Medix™; Harmonville (PA); On-site; USD 70,000 - 100,000; Full time

Job summary

Medix is seeking a compassionate Clinical Research Nurse in Plymouth Meeting, PA to bridge protocol management and high-quality patient care. You will oversee visits, perform procedures, and ensure regulatory compliance throughout trials.

The role requires oncology experience, RN licensure in Pennsylvania, and 2+ years in clinical research or related settings. Onsite, Monday–Friday, with direct hire employment. Strong communication and meticulous record-keeping are essential.

Qualifications

• Active RN license in Pennsylvania required.
• BSN preferred; ongoing professional development encouraged.
• Current BLS certification; ACLS preferred.
• Certification in clinical research is a strong plus.

Responsibilities

• Perform protocol-specified nursing procedures including phlebotomy and IV placement.
• Administer investigational products per protocol and nursing scope.
• Monitor participant safety and document adverse events.
• Complete eCRFs and e-source records per timelines and GCP.
• Coordinate trial materials and collaborate with study team and sponsors.

Skills

Oncology experience

Clinical research experience

IV placement

Phlebotomy

Clinical assessment

Empathetic communication

Education

RN license in PA

BSN preferred

BLS certification

ACLS preferred

OCN/CCRC certification advantage

Tools

EDC systems

eCRF completion

MS Office

Job description

Clinical Research Nurse in Plymouth Meeting, PA

Job Summary

We are seeking a compassionate, detail-oriented Clinical Research Nurse (CRN) with oncology experience to join our clinical trial team. In this role, you will bridge the gap between complex clinical protocol management and direct, high-quality patient care. You will oversee clinical study visits, perform specialized nursing procedures, administer investigational products, monitor participant safety, and maintain strict regulatory compliance.

Clinical Care & Protocol Execution

• Perform protocol-specified clinical procedures, including phlebotomy, peripheral IV insertion, venous blood sampling, biological specimen collection/processing, vital signs, and 12-lead ECGs/EKGs.
• Administer study drugs/investigational products (including oral, subcutaneous, intramuscular, and intravenous therapies) in compliance with protocol guidelines, safety standards, and nursing scope of practice.
• Assess, monitor, and document participant clinical status, vital signs, and potential drug toxicities or treatment responses throughout study visits.

Patient Advocacy & Safety Monitoring

• Conduct the Informed Consent Process in accordance with federal regulations, Good Clinical Practice (GCP), and IRB requirements, ensuring participants fully understand trial participation.
• Continuously monitor participant safety; promptly recognize, assess, and document Adverse Events (AEs) and Serious Adverse Events (SAEs).
• Report SAEs to study sponsors and IRBs within required timeframes (e.g., 24 hours) and immediately notify Principal Investigators (PI) and Sub-Investigators.
• Provide clinical education and guidance to study participants and their families regarding protocol compliance, home drug administration, and potential side effects.

Data Management & Regulatory Compliance

• Maintain comprehensive, accurate, and timely nursing assessments and source documentation.
• Complete Electronic Case Report Forms (eCRFs) and e-source records in accordance with protocol timelines, GCP, FDA, and ICH guidelines.
• Coordinate trial material logistics, ensuring accountability, proper storage, and handling of investigational products, biological samples, and laboratory supplies.
• Collaborate closely with Principal Investigators, Study Coordinators, CROs, and sponsor monitors to ensure trial integrity and data accuracy.

Requirements & Qualifications

Education & Licensure

• Required: Active, unencumbered Registered Nurse (RN) license in the state of Pennsylvania.
• Preferred: Bachelor of Science in Nursing (BSN).
• Certifications: Current BLS required; ACLS preferred. Certified Clinical Research Coordinator/Professional (CCRC/CCRP) or Oncology Certified Nurse (OCN) certification is a strong plus.

Experience & Skills

• Oncology Experience: Minimum of 1-2 years of nursing experience in an oncology setting (inpatient, outpatient infusion, or clinical research).
• Clinical Research Experience: Minimum of 2 years of clinical research experience preferred, with strong working knowledge of ICH/GCP guidelines, FDA regulations, and IRB oversight.
• Clinical Expertise: Advanced proficiency in IV placement, phlebotomy, specimen handling, drug administration, and clinical assessment.
• Technical Skills: Experience with electronic data capture (EDC) systems, e-source reporting, and Microsoft Office Suite.
• Core Competencies: Exceptional critical thinking, organizational skills, acute attention to detail, and empathetic patient communication.
• Job Title: Clinical Research Nurse
• Location: Plymouth Meeting, PA 19462
• Employment: Direct Hire/Permanent Position
• Hours: Monday-Friday; 9AM-5PM; Onsite 5 days a week