Clinical Research Nurse

Actalent; Philadelphia (Philadelphia County); Hybrid; USD 55,000 - 62,000; Full time

Benefits offered by this job

Medical, dental & vision

401(k) Retirement Plan

Life Insurance

Disability insurance

Health Spending Account (HSA)

Transportation benefits

Employee Assistance Program

Paid time off

Job summary

Actalent is seeking a Clinical Research Registered Nurse – Oncology in Philadelphia to support oncology/hematology trials in a leading academic cancer research center. You will coordinate studies, guide patients through complex treatment protocols, and collaborate with physicians and research teams to advance innovative cancer therapies.

The role requires PA RN license, 5+ years RN experience, 2–3 years clinical research, oncology expertise, IRB handling, and GCP knowledge.

Qualifications

• Active RN license in PA.
• Minimum 5+ years RN experience.
• 2–3 years clinical research experience.
• Oncology nursing experience.
• Experience with IRB and informed consent processes.
• Knowledge of GCP guidelines.
• Experience with CTCAE adverse event reporting.

Responsibilities

• Coordinate and support oncology/hematology clinical trials per protocol and GCP.
• Screen patients for eligibility and pre-screening for trials.
• Manage patient enrollment, scheduling, and documentation.
• Obtain informed consent per IRB requirements.
• Provide direct nursing care within a clinical research context.
• Collaborate with physicians and research teams to ensure study operations.
• Monitor adverse events using CTCAE and document them.
• Maintain research records and source documents.
• Educate patients and families about procedures and risks.
• Support trials across malignancies and translational research.
• Participate in quality improvement and compliance activities.

Skills

RN license PA

RN experience 5+ years

Clinical research 2–3 years

Oncology nursing

IRB/consent processes

GCP knowledge

CTCAE adverse event reporting

Patient advocacy

Communication with physicians

Education

BSN preferred

Job description

Job Title: Clinical Research Registered Nurse – Oncology

Job Description

This Clinical Research Registered Nurse role focuses on supporting oncology and hematology clinical trials within a leading academic cancer research environment. You will use your oncology nursing expertise and clinical research experience to coordinate studies, guide patients through complex treatment protocols, and collaborate closely with physicians and research teams. The position plays a key role in advancing innovative cancer therapies, improving patient outcomes, and contributing to high-profile, well-funded research initiatives.

Responsibilities

• Coordinate and support oncology and hematology clinical research studies, ensuring adherence to protocol, Good Clinical Practice (GCP), and regulatory requirements.
• Conduct chart reviews and pre-screen patients to assess eligibility for participation in clinical trials.
• Manage patient enrollment into studies, including scheduling, tracking, and documentation of all study-related activities.
• Obtain and document informed consent from patients in accordance with ethical standards and institutional review board (IRB) requirements.
• Provide direct patient care as a Registered Nurse within the context of clinical research, including monitoring clinical status and supporting treatment plans.
• Collaborate closely and comfortably with physicians, research coordinators, and multidisciplinary team members to ensure smooth study operations.
• Monitor and report adverse events related to cancer medications using CTCAE criteria, ensuring timely and accurate documentation.
• Maintain accurate and detailed research records, including source documents, case report forms, and electronic data capture systems as required.
• Educate patients and families about study procedures, potential risks and benefits, and ongoing participation requirements.
• Support the conduct of innovative clinical trials across a range of genitourinary and other malignancies, contributing to efforts to improve diagnosis and treatment.
• Participate in continuous quality improvement and compliance activities related to clinical research processes and patient safety.
• Contribute to the mission of reducing the burden of cancer by helping translate scientific discoveries into new models of prevention and treatment.

Essential Skills

• Active Registered Nurse (RN) license in the Commonwealth of Pennsylvania.
• 5+ years of experience as a Registered Nurse.
• Minimum of two to three years of clinical research experience.
• Oncology nursing experience, with strong knowledge of cancer care and treatment protocols.
• Comfort and confidence interacting and collaborating with physicians.
• Experience working with institutional review boards (IRB) and informed consent processes.
• Proficiency in patient enrollment and coordination of clinical trial activities.
• Ability to perform chart review and pre-screening of patients for clinical trial eligibility.
• Knowledge and application of Good Clinical Practice (GCP) guidelines.
• Experience with cancer medications and adverse event reporting using CTCAE.
• Strong patient advocacy and communication skills in a research setting.
• Ability to manage multiple studies and patient cases with attention to detail and accuracy.

Additional Skills & Qualifications

• Bachelor of Science in Nursing (BSN) preferred.
• Hematology experience preferred, particularly in the care of patients with hematologic malignancies.
• Background or familiarity with clinical research coordination or study coordination in oncology.
• Experience working on innovative clinical trials, including Phase I–IV studies, is an advantage.
• Understanding of translational research concepts and the integration of laboratory findings into clinical practice.
• Ability to work effectively within large, multidisciplinary academic research teams.
• Strong organizational, documentation, and time-management skills.
• Commitment to the mission of reducing cancer incidence, mortality, and morbidity through research and patient care.

Work Environment

This role is based within a prestigious academic cancer research center that offers a vibrant, well-funded research environment and state-of-the-art equipment. The cancer center supports nearly 200 active clinical trials and holds substantial grant funding from major national organizations, reflecting the high level of research activity. You will work on high-profile studies with large, well-known sponsors, focusing on areas of excellence such as translational research, breast cancer, melanoma, hematologic malignancies and bone marrow transplantation, tobacco-related research, developmental therapeutics, and immunobiology. The environment emphasizes collaboration among physicians, scientists, and research staff to pioneer scientific discoveries and translate them into new models of cancer prevention and treatment. The culture is mission-driven, centered on reducing the burden of cancer while training future cancer researchers and continually improving the ability to prevent, diagnose, and treat cancer. Working hours, shifts, and attire follow typical professional clinical and academic research standards, with an expectation of maintaining a professional appearance appropriate for patient-facing and research activities.

Job Type & Location

This is a Contract to Hire position based out of Philadelphia, PA.

Pay And Benefits

The pay range for this position is $40.00 - $45.00/hr.

Individual compensation offered for this position within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, geographic location, internal equity, and other pertinent job-related factors.

Eligibility requirements apply to some benefits and may depend on your job classification and length of employment. Benefits are subject to change and may be subject to specific elections, plan, or program terms. If eligible, the benefits available for this temporary role may include the following:

• Medical, dental & vision
• Critical Illness, Accident, and Hospital
• 401(k) Retirement Plan – Pre-tax and Roth post-tax contributions available
• Life Insurance (Voluntary Life & AD&D for the employee and dependents)
• Short and long-term disability
• Health Spending Account (HSA)
• Transportation benefits
• Employee Assistance Program
• Time Off/Leave (PTO, Vacation or Sick Leave) Workplace Type This is a hybrid position in Philadelphia,PA. Application Deadline This position is anticipated to close on Sep 30, 2026.

About Actalent

Actalent is a global leader in engineering and sciences services and talent solutions. We help visionary companies advance their engineering and science initiatives through access to specialized experts who drive scale, innovation and speed to market. With a network of almost 20,000 consultants and 5,000 clients across the U.S., Canada, Asia and Europe, Actalent serves many of the Fortune 500. We are proud to be an Engineering News-Record (ENR) Top 500 Design Firm for our engineering design services and a ClearlyRated Best of Staffing® winner for both client and talent service.

The company is an equal opportunity employer and will consider all applications without regard to race, sex, age, color, religion, national origin, veteran status, disability, sexual orientation, gender identity, genetic information or any characteristic protected by law.

If you would like to request a reasonable accommodation, such as the modification or adjustment of the job application process or interviewing process due to a disability, please email [e-mail] for other accommodation options.

San Francisco Fair Chance Ordinance:

Pursuant to the San Francisco Fair Chance Ordinance, for all positions located in the city and county of San Francisco, we will consider for employment qualified applicants with arrest and conviction records.

Massachusetts Lie Detector:

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Use of Artificial Intelligence (AI):

We may use Artificial Intelligence (AI) to support parts of our hiring process, including sourcing, screening, and evaluating candidates. AI helps assess applications and qualifications, but final decisions are made by our hiring team. By applying, you acknowledge and agree that your application may be reviewed using AI tools.