Clinical Research Associate II (CRA II) - 176775

Piper Companies; Orlando (FL); Hybrid; USD 115,000 - 118,000; Full time

Job summary

Piper Companies is seeking a Clinical Research Associate II (CRA II) to support a leading biopharmaceutical organization’s clinical programs. The role involves hybrid monitoring across Florida, Georgia, or Texas, with a preference for Central Florida for Florida-based roles.

The ideal candidate has at least two years of clinical monitoring experience, strong knowledge of GCP, and the ability to manage multiple protocols and sites.

Qualifications

• Bachelor’s degree or equivalent four-year degree required.
• Minimum of 2 years of clinical research monitoring experience as a CRA.
• Experience supporting General Medicine clinical trials preferred.
• Demonstrated experience conducting all types of clinical monitoring visits.
• Ability to independently manage multiple protocols and a portfolio of approximately 8–10 sites.
• Strong knowledge of GCP, clinical trial regulations, monitoring practices, and clinical documentation.
• Willingness and ability to travel approximately 50% of the time.

Responsibilities

• Conduct on-site and remote clinical monitoring visits to ensure compliance with study protocols, GCP, and regulatory requirements.
• Manage a portfolio of approximately 2–3 clinical study protocols and 8–10 investigative sites.
• Perform site initiation, interim monitoring, and closeout visits.
• Monitor site performance, review study documentation, and ensure accurate and complete data.
• Identify and support resolution of protocol deviations and site-level issues.
• Collaborate with clinical operations teams to support study timelines and quality objectives.
• Travel approximately 50% of the time, averaging 6–8 monitoring visits per month.

Skills

Clinical monitoring

CRA experience

Education

Bachelor’s degree or equivalent

Job description

Clinical Research Associate II (CRA II)

Clinical Research Associate II (CRA II)

Location: Florida, Georgia, or Texas (Central Florida preferred for Florida-based roles)

Compensation: Up to $115,000 annually; up to $118,000 for highly qualified candidates

Position Type: Full-Time

Travel: Approximately 50%

Target Start Date: November 9, 2026

About The Opportunity

We are seeking experienced Clinical Research Associate II (CRA II) professionals to support a leading biopharmaceutical organization’s clinical research programs. This is an excellent opportunity to join a collaborative, supportive clinical operations team focused on General Medicine studies.

The ideal candidate will have at least two years of clinical monitoring experience, a strong understanding of clinical trial site management, and experience conducting all types of monitoring visits. This role offers a hybrid monitoring model, a manageable site portfolio, and no on-site productivity metrics.

Key Responsibilities

• Conduct on-site and remote clinical monitoring visits to ensure compliance with study protocols, Good Clinical Practice (GCP), and applicable regulatory requirements.
• Manage a portfolio of approximately 2–3 clinical study protocols and 8–10 investigative sites.
• Perform all types of monitoring visits, including site initiation, interim monitoring, and closeout visits.
• Monitor site performance, review study documentation, and ensure accurate and complete clinical trial data.
• Identify, document, and support the resolution of protocol deviations, compliance concerns, and site-level issues.
• Collaborate with clinical operations teams and investigative site personnel to support study timelines and quality objectives.
• Travel approximately 50% of the time, averaging 6–8 monitoring visits per month.

Required Qualifications

• Bachelor’s degree or equivalent four-year degree required.
• Minimum of 2 years of clinical research monitoring experience as a CRA.
• Experience supporting General Medicine clinical trials preferred.
• Demonstrated experience conducting all types of clinical monitoring visits.
• Ability to independently manage multiple protocols and a portfolio of approximately 8–10 sites.
• Strong knowledge of GCP, clinical trial regulations, monitoring practices, and clinical documentation.
• Willingness and ability to travel approximately 50% of the time.

Additional Details

• Sites will generally be assigned within the CRA’s home state or within a short, direct flight; neighboring states may be included.
• Monitoring will be a combination of on-site and remote visits.
• No on-site productivity metrics.
• Collaborative team environment with a strong emphasis on employee retention and support.

Interested in learning more?

This job opens for applications on 10/17/2026. Applications for this job will be accepted for at least 30 days from the posting date.