Clinical Operations Manager

Scientific Search; Ewing Township (NJ); Hybrid; USD 120,000 - 180,000; Full time

Job summary

Scientific Search is seeking a Clinical Operations Manager to lead end-to-end trial execution across in-house and CRO models in a Hybrid role near Ewing, NJ. You will shape monitoring strategy, ensure inspection readiness, and mentor CRAs while driving RBM and QA across global studies.

With 8+ years in clinical research and 6+ years on-site CRA experience, you’ll partner across Clinical Development, DM, Stats, Safety & Regulatory to deliver compliant, high-quality trials.

Qualifications

• 8+ years in clinical research
• 6+ years on-site CRA experience
• Strong oversight skills (in-house + CRO models)
• Expert in GCP, RBM, and inspection readiness
• Strong communicator, mentor, and cross-functional partner

Responsibilities

• Oversee all operational aspects of trials—from start-up through close-out
• Manage CRAs and IHCRAs; coach, review deliverables, ensure monitoring quality
• Drive CRO oversight: KPIs, governance, performance management
• Ensure TMF accuracy, inspection readiness, and documentation excellence; Lead RBM strategy, SDV/SDR optimization, and centralized monitoring activities
• Support audits/inspections and act as escalation point for complex site issues
• Monitor enrollment, deviations, CAPAs, and timeline risks

Skills

Clinical operations leadership

CRO oversight

RBM monitoring strategy

GCP compliance

Mentoring / coaching

Cross-functional collaboration

Job description

Hybrid –Ewing Area , NJ (Travel Required)

Area clinical operations pro who thrives at the intersection of strategy, oversight, and hands-on leadership? My client—a fast-growing biopharma advancing meaningful global studies—is searching for a Clinical Operations Manager who can elevate trial execution, sharpen CRO performance, and mentor CRAs while keeping every study inspection-ready.

This is your chance to lead high-impact trials across in-house and outsourced models, shape monitoring strategy, and ensure quality that stands up to global regulatory scrutiny.

Why You Should Apply

• Lead complex trials across global regions with true operational authority
• Hybrid role with high visibility and direct influence on clinical success
• Work cross-functionally with Clinical Dev, DM, Stats, Safety & Regulatory
• A culture that values rigor, collaboration, and decisive leadership
• Competitive compensation + excellent benefits (details provided during interview)

What You’ll Be Doing

• Oversee all operational aspects of assigned trials—start-up through close-out
• Manage CRAs and IHCRAs; coach, review deliverables, ensure monitoring quality
• Drive CRO oversight: KPIs, governance, performance management
• Ensure TMF accuracy, inspection readiness, and documentation excellenceLead RBM strategy, SDV/SDR optimization, and centralized monitoring activities
• Support audits/inspections and act as escalation point for complex site issues
• Monitor enrollment, deviations, CAPAs, and timeline risks

About You

• 8+ years clinical research + 6+ years on-site CRA experience
• Strong oversight skills (in-house + CRO models)
• Expert in GCP, RBM, and inspection readiness
• Strong communicator, mentor, and cross-functional partner