Clinical Laboratory Associate, Prenatal

BillionToOne; Union City (CA); On-site; USD 55,000 - 85,000; Full time

Job summary

BillionToOne Inc. is hiring a Clinical Laboratory Associate (CLA) to support daily operations in our Union City lab. This onsite role focuses on pre-analytical testing steps, equipment maintenance, QA procedures, and compliance with lab requirements.

The position offers career growth opportunities and clear tracks tied to performance reviews every six months. Shift hours are Wed-Sat, 10pm–8:30am, with 50% and 55% overnight differentials for Weekday and Weekend shifts respectively.

Qualifications

• Bachelor's degree in biology or related life sciences required.
• Excellent attention to detail is essential.
• Effective written and verbal communication skills are required.
• Ability to multitask and work independently.

Responsibilities

• Perform isolation procedures according to SOPs and CLA responsibilities.
• Maintain equipment according to SOPs.
• Clean labware, equipment, and benches.
• Prepare documents and binders for equipment and personnel records.
• Document corrective actions when test systems deviate from specs.
• Perform and document routine preventative maintenance.
• Prepare reagents required for laboratory preparation.
• Communicate effectively with coworkers and non‑lab personnel.
• Report concerns of accessioning quality and/or safety to leadership.
• Participate in inspection preparation activities.
• Review controlled documents as assigned.

Skills

Attention to detail

Written communication

Verbal communication

Multitasking

Education

Bachelor's degree or equivalent in biology or life sciences

Job description

A Rare Opportunity to Shape the Future of Genomics

Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.

Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.

If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.

We are looking for passionate Clinical Laboratory Associates (CLA) to be responsible for assisting our day-to-day operations, providing equipment maintenance in the clinical laboratory, completing the pre‑analytical phase of testing (e.g., plasma and buffy coat isolation), performing quality assurance procedures, while complying with all local, state, and federal laboratory requirements. The Clinical Laboratory Associate (CLA) is an onsite position at Union City and provides a great opportunity for career growth - at BillionToOne, we offer an array of career growth opportunities and clear growth tracks supported by our performance reviews (every 6 months).

Shift Hours: Wed - Sat, 10pm - 8:30am, 4 days/10 hour shifts

• Weekday Overnight, 50% shift differential

• Weekend Overnight, 55% shift differential

Responsibilities:

• Perform isolation procedures according to the laboratory's standard operating procedures to CLA responsibilities

• Maintain equipment according to the laboratory's standard operating procedures

• Clean labware, equipment, and benches

• Prepare documents and binders for equipment and personnel records

• Document all corrective actions taken when test systems deviate from the established performance specifications

• Perform and document routine preventative maintenance

• Prepare reagents required for laboratory preparation

• Communicate effectively with coworkers and non- laboratory personnel

• Report all concerns of accessioning quality and/or safety to the Laboratory Director, Supervisor, or Safety Officer

• Participate in inspection preparation activities

• Review of controlled documents as assigned

Qualifications:

• Bachelor's degree or equivalent in biology or related life sciences field

• Excellent attention to detail

• Effective written and verbal communication skills

• The ability to multitask and work independently

Nice-To-Haves:

• Biophysics, Molecular biology (DNA purification, PCR, electrophoresis) or next‑generation DNA sequencing laboratory experience

• At least 6 months of experience with molecular biology techniques in a research or clinical laboratory

• Previous clinical laboratory experience is preferred

BillionToOne is a next‑generation molecular diagnostics company on a mission to make powerful, accurate diagnostic tests accessible to everyone. Our revolutionary QCT molecular counting technology enhances disease detection resolution by over a thousandfold using cell‑free DNA,a breakthrough that has already transformed the lives of over half a million patients worldwide.

Our Impact

Unity Complete™ is the only non‑invasive prenatal screen capable of assessing fetal risk for both common recessive conditions and aneuploidies from a single maternal blood sample.
Unity Confirm™ enables non‑invasive confirmation for high‑risk screening results through the capture of intact circulating fetal cells using BillionToOne's Fetal Cell Capture™ Technology.
Our Northstar® liquid biopsy test uniquely combines treatment selection with real‑time monitoring, giving oncologists unprecedented precision in cancer care.

Our Growth

From $0 to $400M+ annualized revenue run‑rate in just 6 years. In 2025, we completed one of the most successful IPOs for a medical diagnostics company, building on nearly $400M in private funding,including our $130M Series D in 2024 and backed by world‑class investors including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

Our Recognition

Forbes named us one of America's Best Startup Employers for 2025 and we're Great Place to Work certified , with 100% of our people willing to go the extra mile, even as we've scaled to over 700 employees.

Our Future

Headquartered in Menlo Park with facilities in Union City, CA, and a new lab opening in Austin, TX in 2027, we're continuing to push the boundaries of what's possible in molecular diagnostics. We're just getting started.