Clinical Genomic Scientist - WGS

Baylor Genetics; United States; On-site; USD 110,000 - 170,000; Full time

Job summary

Baylor Genetics is seeking a Clinical Genomics Scientist II to analyze clinical genetics data, curate variants and genes, and summarize findings for clinical reports. The role supports laboratory directors and R&D with validation of cutting-edge technologies and software platforms.

The position entails curation of variants and gene-disease correlations per ACMG guidelines, analyses of genomic data, and potential participation in report drafting and test validation.

Qualifications

• PhD or MD in clinical medicine, genetics, molecular biology or equivalent.
• Or Master’s degree with relevant experience and 2–4 years of variant curation experience.

Responsibilities

• Curation of variants, genes, and gene-disease correlations following ACMG guidelines (50%).
• Analysis of clinical genomics data and selection of variants for curation/confirmation with HGVS nomenclature.
• May involve clinical report drafting, test validation, process refinement, presenting findings, and monitoring turnaround times.

Skills

Variant curation

Genomics data analysis

HGVS guidelines

Medical writing

Education

PhD in clinical medicine/genetics/molecular biology

MD in clinical medicine/genetics/molecular biology

Master’s degree with relevant experience

Tools

Bioinformatics analysis

Scripting languages

Job description

Job Summary

The Clinical Genomics Scientist II analyzes clinical genetics data, curates variants and genes, and summarizes findings for clinical reports. Our scientists assist laboratory directors and R&D with validation of cutting-edge technologies and software platforms.

Job Summary

The Clinical Genomics Scientist II analyzes clinical genetics data, curates variants and genes, and summarizes findings for clinical reports. Our scientists assist laboratory directors and R&D with validation of cutting-edge technologies and software platforms.

Key Responsibilities

• Curation (50%): curation of variants, genes, and gene-disease correlation following ACMG guidelines.
• Analysis (30%): analyzing clinical genomics data, selecting variants for curation/confirmation, variant nomenclature following HGVS guidelines.
• Other (20%): may involve clinical report drafting, test validation, process refinement, presenting findings, monitoring test turnaround time and task delegation.

Qualifications

Required

• PhD or MD in clinical medicine, genetics, molecular biology or equivalent.

Or

• Strong candidates with a Master’s degree and relevant experience.
• 2-4 years of variant curation experience.

Preferred

• MB(ASCP) certification.

COMPETENCIES

• Familiarity with American College of Medical Genetics (ACMG) variant curation guidelines.
• Knowledge of genomic variation and its correlation with human disease.
• Expertise in concepts of clinical medicine, genetics, genomics, or molecular biology.
• Experience in data quality assessment and communicating genetic details effectively.
• Excellence in reading and writing medical language.
• Proficiency in Microsoft Office (Excel, Word, PowerPoint, Outlook).
• Desired: experience in bioinformatics analysis, variant effect prediction algorithms, and scripting languages.

PHYSICAL DEMANDS AND WORK ENVIRONMENT

• Frequently required to sit, using screen, keyboard, and mouse.
• Punctuality attending virtual meetings.
• Occasional weekend rotation may be needed (for example, once a month).

EEO STATEMENT

Baylor Genetics is proud to be an equal opportunity employer committed to fostering an inclusive and diverse workplace. We welcome and encourage applicants from all backgrounds to apply. We do not discriminate on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, age, veteran status, disability, genetic information, pregnancy, childbirth, or any other status protected by applicable federal, state, or local law. If you need an accommodation during the application process, please contact our Human Resources team.