Clinical Development Head Neuroscience

Biopharma Careers; Cambridge (MA); Hybrid; USD 319,000 - 592,000; Full time

Benefits offered by this job

Health insurance

401(k) matching

Generous paid time off

Job summary

Novartis is seeking a senior clinical leader to shape development strategy for neuroscience programs in the US. You will provide strategic leadership for Global Program Clinical Heads and cross-functional teams, drive study design, biomarkers and evidence generation, and ensure value and access considerations are integrated across the portfolio.

You will oversee resource planning, governance, and professional development of senior clinical leaders, while engaging with regulators, investigators

Qualifications

• MD or equivalent medical degree required with specialty training in neurology, psychiatry, neuroscience or related fields.
• Minimum 10 years in clinical drug development with leadership of global programs and cross-functional teams.
• Deep neuroscience expertise, disease biology, trial design, biomarkers, and data science.

Responsibilities

• Lead the clinical function for the Neuroscience Development Unit with strategic leadership.
• Establish and execute short- and long-term disease area and development strategy.
• Drive development excellence across portfolio: study design, dose selection, endpoints and evidence generation.
• Ensure strategies integrate scientific, regulatory, operational, commercial and patient considerations.
• Oversee resource planning, governance, and leadership development of senior clinical leaders.
• Provide senior clinical oversight for governance, budgeting, regulatory interactions and submissions.
• Represent clinical function in governance forums and collaborate with leadership teams.
• Build relationships with investigators, authorities, patient groups and partners.

Skills

Clinical leadership

Strategy development

Regulatory submissions

Team leadership

Neuroscience expertise

Education

MD or equivalent medical degree

Board certification in neurology/psychiatry or related field

Job description

#LI-HybridAre you ready to shape clinical development strategy and advance innovative medicines for patients living with serious neurological and neuropsychiatric conditions?

Key Responsibilities

• Lead the clinical function for the Neuroscience Development Unit, providing strategic leadership, functional oversight, coaching and performance management for Global Program Clinical Heads and other clinical and medical associates.
• Establish and execute the short- and long-term disease area, portfolio and clinical development strategy in partnership with the Development Unit Head, Global Program Heads and cross-functional leadership.
• Drive clinical development excellence across the portfolio, including study design, protocol strategy, dose selection, biomarker strategy, endpoint selection, evidence generation and application of innovative clinical methodologies and technologies.
• Ensure clinical development strategies integrate scientific, medical, regulatory, operational, commercial, patient, value and access considerations across the full research, development and commercialization continuum.
• Oversee clinical resource planning, organizational effectiveness, workforce deployment and functional excellence to ensure delivery of portfolio and program priorities.
• Develop and strengthen global clinical talent through leadership, succession planning, capability building and mentoring of senior clinical and medical leaders.
• Provide senior clinical leadership for portfolio governance, program prioritization, benefit-risk assessment, investment decisions, regulatory interactions, submissions and key development-stage transitions.
• Represent and advocate for the clinical function within Development Unit and enterprise governance forums, influencing strategic decisions and partnering effectively across Clinical Development and Novartis leadership teams.
• Build and maintain strong relationships with investigators, key opinion leaders, health authorities, patient organizations, alliance partners and other internal and external stakeholders while leading due diligence, business development and licensing activities as required.
• Ensure the highest standards of scientific rigor, patient safety, quality, ethics and compliance while fostering an inspired, curious, collaborative and inclusive culture aligned with Novartis Values and Behaviors.

Essential Requirements

• MD or equivalent medical degree required; board certification and relevant specialty or subspecialty training in neurology, psychiatry, neuroscience or related fields preferred.
• Minimum 10 years of clinical drug development, translational medicine and/or clinical research experience, including leadership of global development programs and multidisciplinary teams.
• Deep expertise in neuroscience and advanced understanding of disease biology, clinical practice, clinical trial methodology, biomarkers, dose selection, biostatistics, data science and emerging technologies supporting clinical development.
• Proven ability to design and implement scientifically robust clinical development strategies that integrate multiple complex dimensions across the research, development and commercialization continuum.
• Significant experience across Phases I-IV clinical development, including regulatory agency interactions, submissions, evidence generation, market access considerations and benefit-risk assessment.
• Demonstrated success leading, developing and inspiring diverse global teams and matrix organizations across multiple geographic regions and functions.
• Strong business acumen and experience supporting portfolio prioritization, governance decision-making, business development, licensing, alliance management, due diligence and M&A evaluations.
• Recognized credibility and influence with physicians, investigators, regulators, scientific experts, key opinion leaders and senior internal stakeholders.
• Outstanding leadership, communication, collaboration and stakeholder management skills, with the ability to influence without authority and drive enterprise-level outcomes in a complex global matrix environment.
• Demonstrated commitment to scientific excellence, patient centricity, quality, compliance, ethics, inclusion and Novartis Values and Behaviors.

Desirable Requirements

• Relevant postgraduate clinical specialty or subspecialty training in neurology, psychiatry, neuroscience or another related medical discipline.
• Medical board certification or an equivalent recognized specialist qualification.

Novartis Compensation and Benefit Summary

• The salary for this position is expected to range between $318,500 - $591,500 per year. The final salary offered is determined based on factors including, but not limited to, relevant skills, experience and geographic location, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.
• Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.
• US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits.
• In addition, employees are eligible for a generous time-off package, including vacation, personal days, holidays and other leaves.
• At Novartis, we are committed to reimagining medicine together and rewarding the people who make it happen.