Chief Medical Officer

Immix Biopharma (Nasdaq: IMMX); Los Angeles (CA); Sur place; USD 400 000 - 900 000; Plein temps

Résumé du poste

Immix Biopharma is seeking a physician leader to serve as Chief Medical Officer. You will guide clinical development across autoimmune and oncology indications, interfacing with sites, CROs and investigators, and shaping the broader development strategy.

The ideal candidate has deep early-to-late-stage development experience, with a track record of advancing precision medicines and a rigorous scientific approach.

Qualifications

• MD/DO/MBBS with fellowship in medical hematology/oncology.
• Five or more years of FDA-facing clinical development experience.
• Deep knowledge of autoimmune diseases and oncology, including drug development paradigms and regulatory approaches.
• Outstanding written and verbal communication skills.
• Ability to drive collaboration and resolve conflicts across stakeholders.
• In-depth understanding of phase I–IV drug development.
• Passion for clinical development and precision medicine with external expert network.

Responsabilités

• Provide leadership to a cross-functional, matrix team of physicians, clinical scientists and other development teams.
• Contribute therapeutic area expertise to enhance trial design and execution.
• Oversee clinical development plans and regulatory documents.
• Lead IND, NDA, BLA submissions with regulatory agency interactions.
• Act as clinical lead for early development studies: design, protocol writing, monitoring and reporting.
• Build relationships with investigators and thought leaders with Medical Affairs collaboration.
• Support scientific advisory boards and external collaborations.

Connaissances

Medical leadership

Clinical development

Regulatory strategy

Cross-functional collaboration

IND/NDA expertise

Formation

MD/MBBS/DO with hematology-oncology fellowship

Description du poste

Immix Biopharma is seeking a motivated physician leader with drug development experience to serve as Chief Medical Officer. This leadership role sits within a growing clinical development organization in the autoimmune and oncology space. You will directly influence the development of our portfolio in autoimmune and oncology indications and help to define the broader clinical development strategy. You will interface with sites, CROs, investigators and advisors. You will collaborate internally with clinical, translational and scientific groups.

The ideal candidate will have deep expertise in early to late-stage clinical development and a demonstrable track record of advancing precision medicines from bench to bedside to approval with strong scientific rigor and a thorough understanding of target and disease biology.

What You Will Do

• Provide leadership to a cross-functional, matrix team of physicians, clinical scientists and other development teams
• Provide specific therapeutic area expertise to enhance innovation and efficiency in clinical trial design and execution
• Responsible for the generation and continual refinement of clinical development plans
• Provide key contribution to IND, NDA, BLA submissions via overseeing medical documentation and active participation in meetings with regulatory agencies
• Clinical lead for early development study conduct including study design, protocol writing, regulatory documents, CRO interactions, study start up, investigator interactions, data monitoring, health authority interactions, analyses and study reports.
• Establish and develop relationships with investigators, thought leaders, in close collaboration with the Medical Affairs function
• Assist in scientific advisory boards, conference activities, external collaborations and partnerships
• Provide medical, disease‑specific, and development perspective into specific research programs or broader research initiatives

What We Look For

• Medical Doctor (MD/MBBS/DO) degree with fellowship training in medical hematology/oncology at a US-accredited program
• Five (5) or more years of FDA‑facing clinical development experience
• Possess a deep knowledge and understanding of autoimmune diseases and oncology, including drug development paradigms, clinical pharmacology and technical, business, and regulatory approaches
• Outstanding interpersonal and communication skills both written and oral and ability to communicate complex information clearly and succinctly
• Effective skills directed toward driving collaboration, achieving results, influencing, and resolving conflicts across internal and external stakeholders
• In depth understanding of phase I-IV drug development
• You are passionate about clinical development and precision, and are well connected to external experts and highly credible advisors in the oncology space
• You have talent and ability in forging and nurturing key partnerships and collaborations with the external scientific community, including academia, governmental organizations, nonprofit organizations and CROs

About Immix Biopharma

Immix Biopharma, Inc. (ImmixBio) (Nasdaq: IMMX) is the global leader in relapsed/refractory AL Amyloidosis. AL Amyloidosis is a devastating disease where the immune system, that’s supposed to protect, instead produces toxic light chains, clogging up the heart, kidney and liver, causing organ failure and death. Our lead candidate is sterically-optimized BCMA‑targeted chimeric antigen receptor T (CAR‑T) cell therapy NXC-201 with a “digital filter” that is designed to filter out non‑specific activation. NXC-201 teaches the immune system to recognize and eliminate the source of the toxic light chains. NXC-201 is being evaluated in the U.S. multi‑center study for relapsed/refractory AL Amyloidosis NEXICART-2 (NCT06097832), with a registrational design. NXC-201 has been awarded Breakthrough Therapy Designation (BTD) and Regenerative Medicine Advanced Therapy (RMAT) by the US FDA and Orphan Drug Designation (ODD) by FDA and in the EU by the EMA.