Cell Therapy Strategy and Commercial Executive Director

AstraZeneca GmbH; Cambridge (MA); Hybrid; USD 268,000 - 402,000; Full time

Benefits offered by this job

In-office three days per week

Incentives and equity-based awards

Retirement benefits

Job summary

AstraZeneca GmbH is seeking a Strategy and Commercial Executive Director for Cell Therapy Strategy and Commercial. You will shape end-to-end strategy across a defined indication, lead global commercial initiatives, and partner with Therapeutic Areas on clinical strategy, pricing, and launch readiness.

You will work with senior leaders to define asset strategies, build evidence from real-world data, and guide cross-functional execution across GCSH, Medical Affairs, and Clinical Strategy teams.

Qualifications

• BA/BS or higher with 10+ years in life sciences or related consulting roles.
• MS/MBA with 8+ years in life sciences or consulting.
• PhD or MD with 5+ years in life sciences or consulting.
• Ability to communicate with senior executive teams; lead and influence professionals.

Responsibilities

• Define and drive end-to-end strategy for a defined indication within Cell Therapy.
• Lead global commercial and strategic initiatives including BD and competitive intelligence.
• Collaborate with Therapeutic Areas on clinical strategy and launch readiness.
• Provide strategic counsel to senior leadership and ensure cross-functional execution.
• Build disease-area strategy content with cross-functional teams.

Skills

Analytical skills

Communication

Strategic thinking

Cross-functional leadership

Business acumen

Education

BA/BS in life sciences or related field

MS/MBA

PhD or MD

Job description

Within the AstraZeneca Cell Therapy Enterprise, our ambition istorealizethe full potential of cell therapy for people living with cancer, immune-mediatedand rare diseases around the world.This unit has responsibility for the value chain from discovery through to late-stage development and commercialization. We are rapidly progressing a broad pipeline of cell therapies in collaboration with AstraZeneca’s Therapeutic Area Units.

The Strategy and Commercial Executive Director, Cell Therapy Strategy and Commercial (CTSC), is a high-impact leadership role accountable for shaping and driving the end-to-end strategy for a defined indication or disease area within Cell Therapy. You will lead global commercial and strategic initiatives within the Cell Therapy Enterprise CTU)—including business development and competitive intelligence—partnering with Therapeutic Areas on clinical strategy, collaborating with in-market commercial and medical affairs on launch readiness, and aligning with global pricing and brand teams. Working cross-functionally with senior leaders, you will define early asset, disease, and portfolio strategies through PH3IDs. Reporting to the VP, Cell Therapy Strategy and Commercial, you will be a key architect of the company’s Cell Therapy strategy and lead cross-functional execution.

Key Accountabilities:

Deliver end-to-end Strategy,including:

• Clear understanding and prioritization of current and future unmet needs

• Indication-level strategic vision for both near-term and long-term

• Integrated clinical strategy across all cell therapy platforms within the same indication
• Work with global Clinical and ClinOps within respective TAs to develop comprehensive development strategy

• Competitive early pipeline / long-term portfolioand life cycle management

• Above-asset initiatives (e.g., Translational Medicine, Precision Medicine, Data Sciences)

Own insights generationfor R&D and commercial activities

• Overseesand guides development and integration of industry-leading competitive intelligence, customer insight, market intelligence and analytics helping the organization to frame business problems and opportunities
• Shape future-proofed strategies and deliver sustainably differentiated brands/early assets, business developmentopportunitiesand TA strategies

• Responsible for the robustness and transparency of the forecasts for PH3IDs
• Bring an intelligence-driven perspective to strategic recommendations by synthesizing insights from diverse sources and publicly available information at the brand and Therapeutic Area level for internal and external communication

• Responsible for creating and curating evidencebankfrom real world data sources to support the PH3ID forecasts created within the team

Lead global commercial cell therapy within indication

• Build the referral capabilities between specific disease areas and the Cell Therapy delivery centers
• Partners closely across different areas of Cell Therapy, Global Commercial, in-market commercial and medical affairs teams to ensure execution of global strategy

• Lead and collaborate with cross-functional teams (e.g., GPTs, Clinical Development, Discovery, BD, Lifecycle and Pipeline, Competitive Intelligence) to develop disease area strategy content

• Provide strategic counselling to Global Clinical Strategy Head (GCSH), Global Commercial and Medical Affairs leadership, and other senior leaders

Basic Qualifications:

• BA/BS and 10 years of experience in life sciences or consulting firm with focus in life science programs

• OR MS/MBA and 8+ years of experience in life sciences or consulting firm with focus in life science programs

• OR PhD or MD and 5+ of experience in life sciences or consulting firm with focus in life science programs

• Ability to interact and communicate effectively with senior executive teams.

• Demonstrated ability to lead and influence experienced professionals.

• Ability to think critically,creativelyand toanticipateand solve problems.

• Ability to navigate and be successful in a fast-paced,highly-matrixedwork environment

Preferred Qualifications:

• Strong analytical and communication skills
• Strong business acumen and strategic thinking skills preferablydemonstratedin apharma relatedenvironment.

• Effective interpersonal and relationship management skills with consultative approach and ability to interact and build trust

• Operational effectiveness, highly organized process with follow through

• Strong initiative to understand our core business goals andestablishprocesses or programs to set direction, generate alignment and push forward

• Financial background and understanding of forecasts, budgets, financialactivitiesand tools

• Resourceful, motivated,influentialand proactive; able to prioritize in a fast-growing organization

• Experience in strategic planning processes and tools

• Scientific background

• Understanding of the pharmaceutical business (including R&D)

• Experience in translating business needs into a coordinated plan from cross-functional senior leadership team

• Ability to develop creative and simple solutions to complex problems

In-Office Working Requirements

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That’s why we work, on average, a minimum ofthree days per weekfrom the office. But that doesn’t mean we’re not flexible. This role can be based in Gaithersburg MD, Boston MA, South San Francisco CA, New York NY.

The annual base pay for this position ranges from $267,914 to $401,870. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

05-Aug-2026

Closing Date

27-Aug-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.