Biotechnician III

BeiGene, Ltd.; Hopewell (VA); On-site; USD 88,456,000 - 122,841,000; Full time

Job summary

BeOne Medicines Ltd. in Hopewell, VA is hiring a Biotechnician III to support the startup of our first US biopharmaceutical plant and then perform hands-on cGMP manufacturing operations.

The role emphasizes compliance, batch documentation, and collaboration across purification, formulation, and fill/finish groups. You will execute media prep, cell culture sampling, harvest operations, equipment sanitation, deviations investigations, and CAPA processes while working with DCS, CIP/SIP systems and

Qualifications

• 3+ years’ experience in biopharmaceutical manufacturing.
• AS/BS/BA in science-related field preferred.
• Ability to communicate effectively, both verbally and in writing.
• Able to work in a fast-paced environment with competing priorities.
• Willing to work any shift; travel (<5%) may be required.

Responsibilities

• Perform hands-on cGMP manufacturing activities to deliver the production plan.
• Follow cGMP procedures for manufacturing execution and documentation.
• Media preparation, transfers, and cell culture sampling.
• Harvest operations and equipment cleaning in purification groups.
• Assist in deviation investigations and CAPA implementation as needed.
• Operate DCS, CIP/SIP, and related equipment.
• Labeling and packaging of finished drug product.
• Complete batch documentation and review records for accuracy.

Skills

cGMP

Bioprocessing

Cell culture

Quality assurance

Documentation

Deviation investigations

CAPA

DCS operation

Autoclave

Gowning

Education

AS/BS/BA in science

High school diploma or GED

Tools

No tools listed

Job description

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.General Description:The Biotechnician III position will directly phase the startup phase of the Hopewell manufacturing facility and then shift focus to hands-on execution and support of cGMP manufacturing operations.Facility Start-Up: Focused on related activities required to design, build, commission, and license BeOne’s first biopharmaceutical plant in the United States.Essential Functions of the Job: include but not limited to:Hands-On cGMP Operations: Focused on execution of cGMP manufacturing activities required to deliver the production plan reliably and compliantly.Follow cGMP procedures to support manufacturing execution and automated recipesMedia preparation & transfers / filtration (if working in cell culture group)Cell culture sampling, monitoring & transferring (if working in cell culture group)Harvest operations (if working in cell culture group)Operational and cleaning of chromatography and filtration system (if working in purification group)Buffer preparation & transfers / filtrationEquipment & process troubleshootingDeviation identification, reporting, drafting, investigate closureChange control drafting, presenting, closurecGMP procedure development and optimizationRequesting, staging, and verifying materials for production activitiesSetup and preparation of equipment for formulation and fillingFinal filtration and formulation of drug productAseptic filling of vials inside a Grade A isolator using automated filling equipment (if working in Drug Product group)Performing in-process visual inspection for quality assurance (if working in Drug Product group)Labeling and packaging of finished drug product in compliance with cGMP (if working in Drug Product group)Completing batch documentation and reviewing records for accuracySupporting routine cleanroom operations, equipment sanitization, and environmental monitoringAssisting in deviation investigations and participating in CAPA implementation as neededOperation of Distributed Computer System (DCS)Operation of equipment’s such as Clean-in-Place (CIP), Steam-in-Place (SIP) skid, Caustic skid, autoclave, part washer, filter integrity tester, biowelders, etc.Cleaning of equipment and facility.Collection of samples for environmental monitoringRemoval of process wasteLeadership Skills:Perform as acting supervisor/leader in the absence of supervisor.Support supervisor managing day to day activities, including staff availability and task loadSelf-directed leadership within both predicable and ambiguous work environmentsThoughtfully escalates issues/concerns in a timely manner as appropriatePhysical Requirements:Must be able to stand for long periods, up to 8 to 10 hours/day.Must be able to reach above shoulder level, bend/stoop, push/pull, and handle/grip frequently.Must be able to work scheduled 40 hours with the ability to work overtime as needed.Must be comfortable in working in varying temperatures.Frequent lifting, pushing, pulling, and carrying. Ability to lift to 40 lbs.Regular reaching, bending, stooping, and twisting.Repetitive motion and substantial movement of the wrists, hands, and/or fingers.Environment requires dedicated gowns, depending on area.Work with hazardous materials and chemicals.Willing to work any shift.Computer Skills: Familiarity with computer-based systems. Word, Excel, and PowerPoint a must.Education Required:High school education or GED and 3+ years’ experience in biopharmaceutical company required.AS/BS/BA in science related field, biopharmaceutical or equivalent technical experience preferred.Other Qualifications:Evidence of good verbal and written communication.Ability to work in fast paced dynamic environment with competing priorities.Demonstrated ability to collaborate within and between diverse groups.Proactive identification and implementation of continuous improvement opportunities.Aptitude for learning moderately complex technical systems.Able to receive and incorporate feedback – passion for ongoing professional development a plus.Travel: International and domestic may be required (< 5%).Global CompetenciesWhen we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.Fosters TeamworkProvides and Solicits Honest and Actionable FeedbackSelf-AwarenessActs InclusivelyDemonstrates InitiativeEntrepreneurial MindsetContinuous LearningEmbraces ChangeResults-OrientedAnalytical Thinking/Data AnalysisFinancial ExcellenceCommunicates with ClaritySalary Range: $30.87 - $42.87 per hourBeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness.We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact [e-mail].