Biostatistics Co-op: Biomarkers, Causal Inference & CoP

Moderna; Cambridge (MA); On-site; USD 28,000 - 83,000; Full time

Benefits offered by this job

Free premium meditation access

Subsidized commuter benefits

Generous PTO and holidays

Job summary

Moderna’s Biometrics organization invites a Biostatistics internship in Cambridge, MA—a full-time co-op from January 18th to June 25th, 2027. You will collaborate with seasoned statisticians to develop, evaluate, and apply fit-for-purpose methods on trial and biomarker data.

You will explore causal inference for surrogate endpoints, perform simulations, and translate statistical insights into development decisions for next-generation mRNA medicines.

Qualifications

• Currently enrolled in a PhD program in Biostatistics, Statistics, Applied Mathematics, Data Science, or a related quantitative field.
• Graduate-level training or research in statistical methodology, including regression, survival analysis, and causal inference.
• Academic or research experience with causal inference and machine learning/deep learning methodologies.
• Proficiency in R (or SAS, Python) for statistical analyses, methodology research, and simulation studies.

Responsibilities

• Develop and apply fit-for-purpose statistical and causal inference approaches to evaluate biomarkers as potential CoP and surrogate endpoints for clinical benefit.
• Explore causal frameworks for surrogate endpoint evaluation, including mediation analysis, controlled efficacy, principal stratification, and other emerging methodologies.
• Design and conduct simulation studies to evaluate statistical properties, operating characteristics, and robustness of proposed methods under clinically relevant scenarios.
• Apply statistical methods to clinical trial and biomarker data to characterize relationships among treatment, immune or biological responses, and clinical outcomes.

Skills

Biostatistics

Causal inference

Regression analysis

Survival analysis

R/Python/SAS

Education

PhD candidate in Biostatistics

Tools

R

Python

SAS

Job description

Moderna’s Biometrics organization invites a Biostatistics internship in Cambridge, MA—a full-time co-op from January 18th to June 25th, 2027. You will collaborate with seasoned statisticians to develop, evaluate, and apply fit-for-purpose methods on trial and biomarker data.

You will explore causal inference for surrogate endpoints, perform simulations, and translate statistical insights into development decisions for next-generation mRNA medicines.