Biologics MES Deployment Lead

GlaxoSmithKline; King of Prussia (PA); On-site; USD 140,000 - 190,000; Full time

Job summary

GlaxoSmithKline is seeking a Biologics MES Deployment Lead to drive MES rollout across US biologics facilities, collaborating with engineering, manufacturing, quality, validation, and IT to ensure compliant and efficient production.

You will partner with Product Owners, Architects, and external vendors to define deployment plans, standardize processes, and apply responsible AI tools while maintaining regulatory and data-security standards.

Qualifications

• Bachelor's degree in engineering or related field.
• 7+ years of experience delivering MES/deployments in regulated environments.
• Experience with GMP-regulated environments and MES validation.

Responsibilities

• Lead MES deployment projects from planning through go-live at biologics sites with cross-functional teams and vendors.
• Define system requirements with manufacturing, quality, and engineering partners to support production and compliance.
• Co-create deployment roadmap and value case with Global MES Lead and Product Owners, tracking paper removal and batch-record cycle time.
• Drive standardization and limit customization across deployments.
• Oversee configuration, testing, validation, and release activities to meet regulatory and user requirements.
• Develop deployment plans, cutover strategies, training materials, and readiness activities for site teams.
• Troubleshoot deployment issues on-site and remotely to minimize production impact.
• Identify opportunities for continuous improvement of MES performance, usability, and integration.
• Lead teams in using approved AI tools while adhering to Responsible AI and security guidelines.
• Collaborate with architects to ensure secure, scalable, and integrated designs.

Skills

Agile Methodology

Cross-Functional Teamwork

Data Analysis

Design Thinking

DevOps

Prioritization

Product Development Research

Product Roadmapping

Project Management

ROI

Software Development

Strategy Deployment

UX

UI Design

Education

Bachelor's degree in Engineering, Life Sciences, Computer Science, Information Technology, or a related discipline

Tools

Emerson DeltaV MES

DCS

ERP

LIMS

DMS

Job description

Business Introduction

GSK remains committed to achieving bold commercial ambitions for the future. By 2031, we aim to deliver 40 billion in annual sales, leveraging our existing strong performance momentum to significantly increase our positive impact on the health of billions of patients globally. Our Ahead Together strategy is centred on early intervention to prevent and alter the course of disease, thereby protecting people and supporting healthcare systems. Our diverse portfolio consists of vaccines, specialty medicines, and general medicines. Through continuous innovation and a dedicated focus on scientific and technical excellence, we strive to develop and launch new, groundbreaking treatments that address critical health challenges.

Job Purpose

The Biologics MES Deployment Lead is accountable for leading the deployment of Manufacturing Execution Systems (MES) for biologics facilities across the United States, including brownfield and greenfield facilities. The role works across engineering, manufacturing, quality, validation, and technology teams to deliver MES solutions that enable safe, compliant, and efficient production.

The Biologics MES Deployment Lead works closely with Product Owners, Business Process Owners, Architects, Engineers, Service Managers, Data and Cyber Security teams, and external partners. The role will also identify opportunities for simplification, standardization, automation, and responsible use of data and AI.

Key Responsibilities

This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following:

• Lead MES deployment projects from planning through go-live at biologics sites, coordinating cross-functional teams and external vendors.
• Define system requirements with manufacturing, quality, and engineering partners to support production and compliance needs.
• Co-create the deployment roadmap and value case for MES at biologics sites with the Global MES Lead and Product Owners, with measures such as paper removed and batch-record cycle time agreed upfront and tracked after go-live.
• Challenge existing ways of working to drive standardization and limit the level of customization across deployments.
• Oversee configuration, testing, validation, and release activities to ensure systems meet regulatory and user requirements.
• Develop deployment plans, cutover strategies, training materials, and support readiness activities for site teams.
• Troubleshoot deployment issues on-site and remotely, driving timely resolution to minimize production impact.
• Identify and drive continuous improvement opportunities to enhance MES performance, usability, and integration with other systems.
• Lead your team in using approved AI tools to improve productivity and ways of working, role-modelling responsible use and following GSK's Responsible AI, privacy, and security requirements.
• Partner with Solution and Enterprise Architects to assess solution options and ensure designs are secure, integrated, scalable, supportable, and aligned with architecture and data standards.
• Coach site teams and junior deployment staff in MES deployment practices and share lessons learned across sites.
• Lead product-level vendor and solution evaluations using transparent, capability-led criteria and contribute to commercial decisions, supplier performance reviews, and lifecycle planning.
• Drive adoption and operational readiness by ensuring business change, training, support models, documentation, release communications, and onboarding needs are reflected in deployment plans.

Why you?

Basic Qualifications

We are looking for professionals with the following required skills to achieve our goals:

• Bachelor's degree in Engineering, Life Sciences, Computer Science, Information Technology, or a related discipline, or equivalent relevant experience.
• 7+ years of experience delivering Manufacturing Execution Systems (MES) or manufacturing systems within biologics, biotechnology, pharmaceutical, or another regulated manufacturing environment.
• Experience with MES configuration, testing, and validation in a GMP-regulated environment.
• Experience supporting biologics manufacturing processes, including batch records and electronic batch record concepts.
• Experience leading cross-functional teams during MES or manufacturing system deployments.
• Experience coordinating third-party vendors during site deployments.
• Experience developing deployment documentation and training end users.
• Experience integrating MES with manufacturing or enterprise systems such as DCS, ERP, LIMS, or DMS.
• Experience with SDLC documentation and validation requirements within a regulated manufacturing environment.
• Experience managing technical projects using formal project management methodologies to track scope, schedule, progress, and risk.

Preferred Qualifications

If you have the following characteristics, it would be a plus:

• Master's degree in Engineering, Life Sciences, Computer Science, Information Technology, or a related discipline.
• Experience with Emerson DeltaV MES (previously Syncade) or other commercial MES solutions.
• Experience leading digital transformation initiatives that transition manufacturing processes from paper-based to recipe-driven manufacturing.
• Experience applying automation or approved AI tools to support MES deployment activities.
• Experience with enterprise architecture, systems integration, data, cyber security, validation, service management, and operational resilience.
• Experience evaluating solution cost, value, benefits, risk, and total cost of ownership.
• Experience working with senior functional stakeholders in a matrixed organization.
• Project management, validation, or relevant MES vendor certification or training.

#GSK-LI #AGTech

Skills

Agile Methodology, Cross-Functional Teamwork, Data Analysis, Design Thinking, DevOps, Prioritization, Product Development Research, Product Roadmapping, Project Management, Return on Investment (ROI), Software Development, Strategy Deployment, User Experience (UX), User Interface (UI) Design

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases - to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/