Biologics Formulation Intern

Zoetis, Inc; Kalamazoo (MI); Sur place; USD 22 000 - 50 000; Plein temps

Résumé du poste

Zoetis, Inc. in Kalamazoo, MI seeks a Biologics Formulations Summer Intern to develop a rapid NIR-based moisture analysis tool for lyophilized products. You will prepare samples, collect KF and NIR data, and build chemometric models to predict moisture and improve lyophilization processes.

The role focuses on data-driven formulation research, stability, and product quality, with hands-on lab work and technical reporting across a 10–12 week window.

Qualifications

• Experience working in a laboratory setting and recording data.
• Interest in Lyophilization techniques, PAT, spectroscopy (NIR/IR).
• Comfortable with data (e.g. Excel, JMP).
• Detail-oriented, able to document experimental work.

Responsabilités

• Familiarize and operate lyophilization equipment and prepare samples across moisture targets.
• Perform Karl Fischer titration and acquire NIR spectra.
• Develop and evaluate chemometric models (PLS) correlating NIR spectra with KF moisture.
• Process and analyze experimental data; assess model performance.
• Document findings and support technical reports and presentations.

Connaissances

Laboratory experience

Data handling (Excel/JMP)

Analytical chemistry concepts

Communication skills

Formation

Bachelor's in Pharmaceutical Sciences or related

Outils

Karl Fischer titration

NIR spectroscopy

Lyophilization equipment

Chemometric modeling (PLS)

Description du poste

Role Description:

We are seeking a talented Biologics Formulations Summer Intern to join our team and contribute to the development of a robust moisture-prediction model for lyophilized drug products. In this role, you will support formulation development and data-driven research efforts aimed at improving the stability, quality, and performance of lyophilized pharmaceuticals.

Biologics Formulation Intern: Advancing Moisture Analytics: Development of a NIR Spectroscopy Method and Chemometric Model for Lyophilized Biopharmaceutical Products

Location: Kalamazoo, Michigan

Internship Summary:

This 10-12-week internship will focus on developing a rapid, non-destructive Near-Infrared (NIR) spectroscopy method to measure moisture content in lyophilized drug products as a Process Analytical Technology (PAT) tool. The intern will prepare samples across a range of moisture levels, collect paired Karl Fischer (KF) and NIR data, and develop and evaluate a chemometric model, such as partial least squares (PLS) regression. The project aims to enable faster, more efficient moisture analysis and support the future implementation of 100% vial testing and improved lyophilization process development.

Internship Job Duties:

• Familiarize and operate freeze-drying/lyophilization equipment and prepare formulations across a defined range of moisture-content targets.


• Perform Karl Fischer (KF) titration and acquire Near-Infrared (NIR) spectra using established sample-handling and laboratory procedures.


• Develop, optimize, and evaluate chemometric models-such as PLS regression-to correlate NIR spectra with KF moisture measurements.


• Process and analyze experimental data, assess model performance, and support method optimization to minimize false-positive and false-negative results.


• Conduct laboratory experiments under supervision, document findings, and contribute to technical reports and posters/presentations and analytical-method documentation supporting future PAT implementation.

Internship Qualifications:

• Currently enrolled in a bachelor's degree in Pharmaceutical Sciences, Analytical Chemistry, Chemical/Biomedical Engineering, or a related field


• Experience working in a laboratory setting, operating laboratory equipment, recording data


• Interested in learning Lyophilization techniques, PAT, spectroscopy (NIR/IR), and/or analytical methods


• Comfortable working with data (e.g. Excel, JMP, or similar)


• Detail-oriented, structured, and able to document experimental work


• Effective communication skills

The following hourly pay rates reflect the anticipated base pay for this position:

If the selected candidate is a student pursuing an Associate-level degree: $16.00 per hour

If the selected candidate is a student pursuing an Undergraduate-level degree: $22.00 per hour

If the selected candidate is a student pursing a Graduate-level degree: $32.50 per hour

If the selected candidate is a student pursuing a Doctorate-level degree: $36.00 per hour

The following hourly pay rates reflect the anticipated base pay for this position if a selected candidate were to be located in California, Connecticut, District of Columbia, Illinois (Chicago area), Massachusetts, New Jersey, New York, Washington (Seattle area):

Student pursuing an Associate-level degree: $17.00 per hour

Student pursuing an Undergraduate-level degree: $24.20 per hour

Student pursing a Graduate-level degree: $36.40 per hour

Student pursuing a Doctorate-level degree: $40.30 per hour

Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability. Please contact Zoetis Colleague Services at [e-mail] to request an accommodation. Zoetis also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must possess or obtain authorization to work in the US for Zoetis. Zoetis retains sole and exclusive discretion to pursue sponsorship for the acquisition or maintenance of nonimmigrant status and employment eligibility, considering factors such as availability of qualified US workers. Individuals requiring sponsorship must disclose this fact. Please note that Zoetis seeks information related to job applications from candidates for jobs in the U.S. solely via the following: (1) our company website at www.Zoetis.com/careers site, or (2) via email to/from addresses using only the Zoetis domain of "@zoetis.com". In addition, Zoetis does not use Google Hangout for any recruitment related activities. Any solicitation or request for information related to job applications with Zoetis via any other means and/or utilizing email addresses with any other domain should be disregarded. In addition, Zoetis will never ask candidates to make any type of personal financial investment related to gaining employment with Zoetis.