Bioinformatics Scientist - Pipeline Development

Axtria; United States; Remote; USD 80,000 - 120,000; Full time

Job summary

An established industry player is seeking a Bioinformatics Scientist to join their dynamic team at a prestigious research institute. This role involves addressing complex bioinformatics needs, supporting high-throughput genomic analyses, and collaborating with leading scientists to drive innovative research. The ideal candidate will leverage their expertise in bioinformatics and programming to develop and maintain robust pipelines, contributing to impactful scientific publications. Join a forward-thinking company committed to advancing healthcare through data science and research excellence, all while enjoying the flexibility of remote work.

Benefits

100% Medical, Dental & Vision Coverage for Employees

Paid Time Off and Paid Holidays

401K match up to 5%

Educational Benefits for Career Growth

Employee Referral Bonus

Flexible Spending Accounts

Qualifications

• 4+ years of experience in bioinformatics with expertise in NGS analysis.
• Strong programming skills in Python, R, or C/C++ required.

Responsibilities

• Provide bioinformatics support for high-throughput genome-scale technologies.
• Contribute to the development of scalable resources for NGS bioinformatics.

Skills

Bioinformatics

Statistical modeling

Scripting

Biological interpretation

Programming (Python, R, C/C++, sh/bash)

Education

Bachelor's degree in related field

Master's or Ph.D. preferred

Tools

Docker

Snakemake

Nextflow

AWS

GCP

Azure

Job description

Overview

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Axle is seeking a highly ambitious, adaptable, structured, and detail-oriented Bioinformatics Scientist-Pipeline Development to join our vibrant team at the National Institutes of Health (NIH), National Institute of Allergy and Infectious Diseases (NIAID), Division of Intramural Research (DIR), Research Technologies Branch (RTB), Integrated Data Sciences Section (IDSS) in Bethesda, MD. *Work remote*

Benefits We Offer:

• 100% Medical, Dental & Vision Coverage for Employees
• Paid Time Off and Paid Holidays
• 401K match up to 5%
• Educational Benefits for Career Growth
• Employee Referral Bonus
• Flexible Spending Accounts:
  • Healthcare (FSA)
  • Parking Reimbursement Account (PRK)
  • Dependent Care Assistant Program (DCAP)
  • Transportation Reimbursement Account (TRN)

Responsibilities:

• Address bioinformatics, scientific computing, and data analysis needs of users within the Division of Intramural Research (DIR) at NIAID and their collaborators by lending expertise in the proper statistical design of biological experiments involving high-throughput genome-scale technologies, data mining and knowledge discovery techniques, automated workflow development, statistical and scientific experimental design consulting. Provide bioinformatics support to include somatic and germline variant calling and analysis, single-cell and bulk gene expression analysis, de novo assembly of genomes and transcriptomes, comparative genomics of model and non-model organisms, proteomics, ChIP-seq, ATAC-seq, and the development of high-throughput pipelines for the analysis of the above data modalities.
• Provide programming and troubleshooting support to the Research Technologies Branch (RTB) of the National Institute of Allergy and Infectious Diseases (NIAID) and collaborating Institutes in the dissemination of research data. Perform computational data analysis on genomic and clinical research data. Work with staff on scientific programming and experimental design. Provide statistical support/analysis on research data. Contribute to and co-author scientific publications in leading peer-reviewed journals.
• Contribute to the development of a scalable and flexible resource to provide NGS bioinformatics, structural biological and computational, machine learning data support to NIAID scientists and investigators. It is expected that the bioinformatics scientist will need strong skills in the following:
  • NGS analysis (whole-exome, whole-genome, RNA-seq, ChIP-Seq, both long- and short-read technologies, etc.)
  • Statistical modeling
  • Scripting
  • Biological interpretation

Specific Qualifications:

• Ability to obtain and maintain a Public Trust Security clearance
• Minimum Bachelor’s degree in related field, Master’s or Ph.D. preferred
• 4+ years of experience in bioinformatics
• 2+ years of experience developing and maintaining production bioinformatics pipelines
• Expert in two (2) of the following languages: Python, R, C/C++, sh/bash
• Experience building images using one (1) of the following: Docker, Podman, Singularity/Apptainer
• Expert in one (1) pipeline framework: Snakemake, Nextflow, CWL/WDL
• Expertise building technical and user documentation for tools, pipelines, and applications
• Experience building pipelines locally on-premise using available HPC infrastructure
• Experience building pipelines/applications in the Cloud with AWS/GCP/Azure is a plus
• Experience building applications using one (1) of the following frameworks is a plus: Django, Flask, RShiny, Electron, Flutter, React
• Experience working in a laboratory setting is a plus but not required

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on