Bioinformatics Scientist (51683)

GAP SOLUTIONS INC; North Carolina; On-site; USD 110,000 - 128,000; Full time

Job summary

GAP Solutions Inc. seeks an Experienced Bioinformatics Scientist to support NIEHS within NIH at RTP, NC. Lead analyses of NextGen sequencing data and integrate genomics findings with biological interpretation.

The role emphasizes collaboration with biologists, data-driven reporting, and workflow development. A Ph.D. in a related field and strong programming in R, Python, MATLAB, and Linux are required.

Qualifications

• Ph.D. in Bioinformatics, Biostatistics, Computational Biology or related field.
• Experience with R, Python, MATLAB, Java.
• Experience with Linux, Unix, Shell, PERL.
• Skilled in Next Gen sequencing data analysis (RNA-Seq, ChIP-Seq, etc).
• Skilled in analyzing large genomic datasets and multi-omics data.

Responsibilities

• Coordinate with biologists to design models that explain experimental data.
• Prepare reports and publication quality graphics from experiments.
• Present findings in meetings with biologists and groups.
• Develop workflows for data quality, genome integration and analyses.
• Write scripts and custom programs to support discovery.
• Analyze differential gene expression; compute fold changes and p-values.

Skills

R

Python

MATLAB

Java

Education

Ph.D. in Bioinformatics or related field

Tools

NextGen sequencing

ChIP-Seq RNA-Seq analysis

Job description

Job DetailsLevel: ExperiencedJob Location: National Institutes of Health - Research Triangle Park NIEHS - Research Triangle Park, NC 27709Position Type: Full TimeEducation Level: Ph.D.Salary Range: $110,000.00 - $128,000.00 Salary/monthTravel Percentage: NoneJob Shift: DayJob Category: Public Health

Position Objective: The Bioinformatics Scientist will provide support to the National Institute of Environmental Health Sciences (NIEHS) within the National Institutes of Health (NIH).

Duties and Responsibilities:

• Coordinate with biologists and/or other bioinformaticians in the design of models summarizing and explaining experimental data, provide interpretive analyses of data derived from different experimental platforms to generate biological meaning
• Prepare reports and publication quality graphics summarizing experimental data including providing written documents
• Participate in meetings with biologists; present findings to individuals and groups
• Conduct analyses on NextGen sequencing data including data derived in ChIP-Seq, RNA-Seq, miRNA-Seq and other experimental models 1
• Conduct analysis and interpretation on data from genomic platforms including expression, exon, tiling, promoter and others array types 2
• Conduct data analysis and interpretation on other large data types in genomic context 3
• Establish and maintain workflows including experimental design, analyses of data quality, genome and meta-genome integration and others 4
• Write utility scripts, macros and/or custom programs or algorithms in support of biological discovery 5
• Work products and documents related to conducting data analyses on NextGen sequencing data; analyzing and interpreting data from genomic platforms, including expression microarrays and others.
• Work products and documents related to identifying and discovering analyses of differentially expressed genes; calculating fold change, p-values, multiple test adjustments and custom analyses; conducting data quality analyses/assessments, analyses of raw and normalized data using graphical techniques.
• Work products and documents related to developing and/or managing workflows, experimental design, analyses of data quality, genome and meta-genomic context and others.
• Work products and documents related to writing custom programs and algorithms; designing models summarizing/explaining experimental data; preparing reports and publication quality graphics; participating in meetings.

QualificationsBasic Qualifications:

• Ph.D. in Bioinformatics, Biostatistics, Computational Biology or a biological/life science with a field of study in Biology, Environmental Science, Genetics, Molecular Biology, Mathematics and Computer Science, or similar.
• Experience with R, Python, MATLAB, Java
• Experience with Linux, Unix, Shell, PERL
• Skilled in Next gen sequencing data analysis: Bulk RNA-Sequencing, Next gen sequencing data analysis, and Clinical and/or translational research
• Skilled in Single Cell RNA-Sequencing, working with large data sets, Microarray data analysis, and Pipeline development
• Skilled in Methylation Analysis, Multi-omics Analysis, Cluster Analysis, and Core facility

Preferred Qualifications:

• Ability to communicate effectively, orally and in writing, with non-technical and technical staff
• Detail-oriented and possess strong organizational skills with the ability to prioritize multiple tasks and projects

*This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required by this position.

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status or other characteristics protected by law.

This position is contingent upon contract award.