Biochemist I

Meso Scale Diagnostics LLC; Rockville (MD); On-site; USD 52,000 - 76,000; Full time

Benefits offered by this job

401(k) matching

Paid vacation

Paid sick leave

Paid holidays

Parental leave

Disability insurance

Life insurance

Job summary

Meso Scale Diagnostics LLC in Rockville, MD, is seeking a Manufacturing Associate to support production of immunoassay kits in a GMP environment. You will operate instruments and perform gel filtration, centrifugation, spectrophotometry, reconstitution, and various assays to ensure high-quality products.

Responsibilities include buffer exchanges, antibody conjugation with Biotin or NHS-ester, protein quantification, and meticulous documentation in a cleanroom setting.

Qualifications

• Bachelor's degree or equivalent work experience in a related field.
• internship experience in relative field is highly desirable.

Responsibilities

• Buffer exchanges protein solutions via spin column gel filtration to prepare conjugation/coating solutions or remove free-tag.
• Conjugates antibodies with Biotin or SULFO-TAG NHS-Ester to produce detection/capture antibodies for kits.
• Reconstitutes antibody materials for use in conjugation and buffer exchange procedures.
• Quantifies protein concentrations via spectrophotometry or BCA assay.
• Runs assays to quantify biotin/protein ratios or glycerol content.
• Participates in developing solutions to improve routine manufacturing initiatives.
• Completes documentation to support procedures including data entry and batch records.
• Performs daily maintenance and documentation of production equipment.
• Participates in general lab maintenance including cleanliness, supplies and equipment.
• Prepares and reports raw material inventories.
• Participates in year-end physical inventory.
• Specific duties may vary.

Skills

Laboratory techniques

cGMP/ISO knowledge

Communication skills

Multi-tasking

Safety compliance

Analytical mindset

Education

Bachelor's degree in Biology, Chemistry, Biotechnology, Engineering or related field

Associate's degree with equivalent work experience

Tools

JDE

MS Office

Job description

POSITION SUMMARY:

This job is responsible for manufacturing products using instruments and biochemical processes. The incumbent will utilize techniques such as gel filtration, centrifugation, spectrophotometry, reconstitution, and various assays.

DUTIES AND RESPONSIBILITIES:

• Buffer exchanges protein solutions via spin column gel filtration to prepare conjugation/coating solutions or remove free-tag.


• Conjugates antibodies with Biotin or SULFO-TAG NHS-Ester in order to produce detection/capture antibodies for use in catalog and custom kits.


• Reconstitutes antibody materials for use in conjugation and buffer exchange procedures.


• Quantifies protein concentrations utilizing techniques such as spectrophotometry or BCA Assay.


• Runs assays to quantify biotin/protein ratios or glycerol content in solution.


• Participates in developing solutions to improve routine manufacturing initiatives that provide for better quality and quantity of products.


• Documentation
  
  
  
  • Completes appropriate documentation to support process and production procedures including data entry and production batch records.
  
  
  • Performs daily maintenance and documentation of all production equipment.
  
  
  
  


• Participates in general laboratory maintenance including maintaining laboratory cleanliness, supplies and equipment.


• Prepares, maintains and reports raw material or reagent inventories.


• Participates in year-end physical inventory.


• Specific duties may vary depending upon departmental requirements.

EXPERIENCE AND QUALIFICATIONS:

• Bachelor's degree in Biology, Chemistry, Biotechnology, Engineering or related field; or an Associate's degree with equivalent applicable work experience.


• Internship experience in relative field is highly desirable.


• Prior manufacturing experience is a plus.

KNOWLEDGE, SKILLS AND ABILITIES:

• A demonstrated aptitude for learning and adhering to standard laboratory techniques and safety precautions.


• Knowledge of JDE is preferred.


• Knowledge of cGMP and/or ISO certification is highly preferred.


• Ability to learn additional software applications/tools, as required.


• Ability to follow laboratory safety instructions; ability to use protective equipment.


• Knowledge of scientific fundamentals and possess a strong analytical background.


• Mechanical aptitude including equipment troubleshooting.


• Excellent oral, written communication and interpersonal skills.


• Ability to effectively communicate issues/problems and results that impact timelines, accuracy and reliability of laboratory data.


• Proficiency in MS Office Suite.


• Ability to multi-task and work productively in a demanding manufacturing environment with changing priorities.

PHYSICAL DEMANDS:

• This position requires the ability to communicate and exchange information, utilize equipment necessary to perform the job, and frequent lifting up to 25 lbs.


• Up to 80% of the day may be spent at a lab bench and/or in the cleanroom.

WORK ENVIRONMENT:

Standard industrial laboratory environment

COMPENSATION SUMMARY:

The annual base salary for this position ranges from $52,400 to $76,000. This salary range represents a general guideline as MSD considers other factors when presenting an offer of employment, such as scope and responsibilities of the position, external market factors, and the candidate's knowledge, skills, abilities, education and experience. Employees may qualify for a discretionary or non-discretionary bonus in addition to their base salary. These annual bonuses are intended to recognize individual performance and enable employees to benefit from the Company's overall success.

BENEFITS SUMMARY:

At MSD, we offer a comprehensive benefits package to support our employees' well-being and financial security. In addition to competitive salaries, our benefits include medical, dental, and vision coverage, along with prescription benefits. We provide a 401(k) plan with company matching, flexible spending accounts, and company-paid short- and long-term disability insurance as well as group life and accidental death and dismemberment insurance. Our offerings also encompass paid vacation, paid sick leave, paid holidays, and paid parental leave, along with an employee assistance program. Additional voluntary perks include a fitness club membership contribution, pet insurance, identity theft protection, home and auto insurance discounts, and optional supplemental life insurance.

EEO/AA STATEMENT:

MSD is an Equal Opportunity/Affirmative Action Employer. We are committed to fostering a diverse and inclusive workplace where all individuals are treated with respect and dignity. We welcome applications from all qualified candidates, making employment decisions without regard to race, color, religion, creed, sex, sexual orientation, gender identity, genetic information, marital status, national origin, age, protected veteran status, pregnancy, disability status, or any other protected characteristic. For our full EEO/AA and Pay Transparency statement, please click on the following link: https://www.mesoscale.com/en/our_company/careers/equal_employment_opportunity_statement.

Meso Scale Diagnostics uses E-Verify to validate the work eligibility of candidates.

This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights notice from the Department of Labor.