Associate Scientist – Solid State Characterization

Eurofins; New London (CT); On-site; USD 65,000 - 86,000; Full time

Benefits offered by this job

Medical, dental, and vision options

Life and disability insurance

401(k) with company match

Paid vacation and holidays

Job summary

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer. The Associate Scientist will provide laboratory support in synthesizing salt forms and polymorphs of drug candidates and evaluate these forms for acceptability as drug substances.

The role focuses on solid form characterization and particle characterization, based in Groton, CT (USA), with daily responsibilities across multiple analytical techniques and collaboration with cross-disciplinary

Qualifications

• BS with 2+ years of experience or MS in pharmaceutical science, chemistry, chemical engineering, or related field.
• Experience with solid state characterization techniques (X-ray powder diffraction, polarized light microscopy, DSC, TGA, spectroscopy, etc.). Strong data analysis and interpretation skills.
• Experience and understanding of infrared spectroscopy (FTIR, NIR, FT-Raman) and/or SSNMR is an advantage.
• Experience with solving Materials Science problems via experimental approaches and teamwork.
• Understanding of physical, analytical, and organic chemistry.
• Good organizational skills, ability to work independently, and excellent oral and written communication skills.
• Strong interest in learning new technologies; programming experience is a plus.

Responsibilities

• Conduct solid state characterization (e.g., X-ray powder diffraction, thermal analysis, moisture sorption, microscopy, spectroscopy) of small molecules of pharmaceutical relevance.
• Support multidisciplinary project teams and collaborate to define and implement crystallization, polymorph, salt, and co-crystal screening activities according to project timelines.
• Support API particle characterization activities according to project timelines.
• Conduct physical and surface characterization of powders, including particle size, shape, surface energy and roughness.
• Collaborate with Medicinal Chemistry, Formulation and Biopharmaceutics to align screening and characterization strategies with solid form selection for clinical studies.
• Solve scientific problems using contemporary Materials Science experimental techniques.
• Contribute to development of new scientific approaches within Materials Science organization.
• Maintain contemporaneous and accurate entries in the electronic laboratory notebook per good practice.

Education

Bachelor’s or Master’s degree in pharmaceutical science/chemistry/chemical engineering or related field

Job description

Company Description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate. The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products. In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products. In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years.

Job Description

The Associate Scientist provides laboratory support in synthesizing salt forms and polymorphs of drug candidates and evaluates these forms for acceptability as drug substances with respect to chemical manufacturing and formulation into pharmaceutical products. The successful candidate will engage in solid form characterization and in particle characterization. The position is based in Groton, CT (USA).

Role Responsibilities

• Conduct solid state characterization (e.g., X-ray powder diffraction, thermal analysis, moisture sorption, microscopy, spectroscopy) of small molecules of pharmaceutical relevance.
• Support multidisciplinary project teams and collaborate with colleagues to define and implement crystallization, polymorph, salt, and co-crystal screening activities according to project timelines.
• Support multidisciplinary project teams and collaborate with colleagues to define and implement API particle characterization activities according to project timelines.
• Conduct physical and surface characterization of powders of pharmaceutical relevance. This includes particle characterization (e.g., particle size, shape) and surface characterization (e.g., surface energy, surface roughness).
• Collaborate with colleagues in Medicinal Chemistry, Formulation and Biopharmaceutics to define and implement screening and characterization strategies consistent with solid form selection for clinical studies.
• Solve scientific problems using contemporary Materials Science experimental techniques.
• Contribute to the development of new scientific approaches and knowledge within the Materials Science organization.
• Ensure contemporaneous and accurate entries are made in the electronic laboratory notebook system according to accepted good practice.

Qualifications

• Bachelor's Degree (BS) with 2+ years of experience or a Master's degree (MS) in pharmaceutical science, chemistry, chemical engineering, or related field.
• Strong pharmaceutical, API, small molecules testing for drug production is strongly preferred
• Experience in solid state characterization techniques (such as x-ray powder diffraction, polarized light microscopy, differential scanning calorimetry, thermogravimetric analysis, spectroscopy, etc.). Strong data analysis and interpretation skills.
• Experience and understanding of infrared spectroscopy (FTIR, NIR, FT-Raman) and/or SSNMR is an advantage.
• Experience with solving Materials Science problems, e.g., solid state chemistry and particle characterization using experimental approaches and team collaboration.
• Understanding of physical, analytical, and organic chemistry.
• Good organizational skills, the ability to work independently, and excellent oral and written communication skills are required.
• A strong interest and motivation to learn new technologies and concepts is expected.
• Some programming experience is a plus, but not required.

Additional Information

• Position is Monday-Friday 8:00am-5:00pm Overtime as needed
• May be requested to work on weekends, overtime, and holidays based on business needs
• Candidates currently living within a commutable distance of Groton, CT are encouraged to apply.
• Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays
• Authorization to work in the United States indefinitely without restriction or sponsorship

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.