Associate Scientist- Oncological Sciences

Mount Sinai; New York (NY); On-site; USD 59,000 - 99,000; Full time

Job summary

Mount Sinai seeks an Associate Scientist experienced in human disease biology and stem cell models. You will maintain and expand iPSC cultures, reprogram patient cells, and perform routine cell culture and molecular biology experiments under established protocols.

You will mentor junior staff, contribute to grant applications and scientific communications, and help ensure biosafety and quality standards while pursuing advances in stem cell biology and organoid technologies.

Qualifications

• PhD required with at least three years of experience.
• Strong experience in mammalian cell culture and stem cell methods.
• Ability to design, execute, troubleshoot, and optimize complex experiments.

Responsibilities

• Maintain and expand human iPSC cultures.
• Reprogram patient cells to generate new iPSC lines.
• Perform routine cell culture procedures (passaging, freezing, thawing, counting).
• Differentiate iPSCs into hematopoietic stem cell types.
• Prepare media, reagents, and cell culture materials.
• Conduct general molecular and cellular biology experiments with established protocols.
• Monitor morphology, viability, and culture quality.
• Maintain accurate experimental records and documentation.
• Follow strict sterile and aseptic procedures.
• Assist with lab purchasing, reagent prep, and routine maintenance.
• Develop and optimize differentiation protocols and cellular assays.
• Contribute to grant applications, reports, manuscripts, and presentations.
• Mentor research associates and junior staff; supervise when needed.
• Assist with lab management and biosafety compliance.
• Stay current with advances in stem cell biology and organoid technologies.

Skills

iPSC reprogramming

cell culture

molecular biology

genome editing

flow cytometry

qPCR

mentoring

project management

scientific writing

mice handling

Education

Ph.D. in Biological Science or related field

Tools

Microsoft Office

Job description

Description

Job Description

The Associate Scientist is experienced in the conduct of research involving the understanding of human diseases and improvement of human health. May assist in the operation of the clinical laboratory. Engages in clinical investigation or other research, production, technical writing, and related activities, and may mentor less senior scientist and Associate Researcher staff.

Responsibilities

• Maintaining and expanding human iPSC cultures.
• Reprogramming patient cells to generate new iPSC lines.
• Perform routine cell culture procedures, including passaging, freezing, thawing, and cell counting.
• Perform differentiation of iPSCs into hematopoietic stem cell types
• Prepare media, reagents, and cell culture materials.
• Perform general molecular and cellular biology experiments according to established protocols.
• Monitor cell morphology, viability, and culture quality.
• Maintain accurate experimental records and documentation.
• Follow strict sterile and aseptic working procedures.
• Assist with laboratory purchasing, organization, reagent preparation, and routine maintenance.
• Developing and optimizing differentiation protocols, cellular assays, and quality control strategies to generate reproducible, scalable, and biologically relevant stem cell-derived models.
• Contributing to grant applications, technical reports, manuscripts, presentations, SOP development, and scientific communications.
• Mentoring research associates, trainees, and junior scientists while fostering a collaborative and innovative laboratory environment.
• May supervisor junior level research staff
• Assisting with laboratory management, including implementation of new technologies, oversight of laboratory resources, and ensuring compliance with biosafety and quality standards.
• Remaining current with advances in stem cell biology, developmental biology, and organoid technologies, and implement emerging methodologies.

Qualifications

• Ph.D. in Biological Science or related field
• Three years experience.

Preferred Skills

• Must possess basic Microsoft Office skills.
• Demonstrated expertise in mammalian cell culture, aseptic technique, and advanced molecular and cellular biology methodologies.
• Demonstrated experience with human iPSC reprogramming, culture, characterization, genome editing, and directed differentiation.
• Experience designing, executing, troubleshooting, and optimizing complex scientific experiments independently.
• Strong organizational and project management skills with the ability to lead multiple projects simultaneously.
• Excellent written and verbal communication skills, including preparation of manuscripts, technical reports, and scientific presentations.
• Experience mentoring junior scientists or research staff.
• Experience with molecular and cellular biology techniques such as qPCR, flow cytometry, RNA analysis, plasmid construction.
• Strong organizational, communication, and problem-solving skills.
• Ability to work independently while contributing effectively within a collaborative research environment.
• Strong scientific publication record appropriate to career stage.
• Experience with handling mice.

Employer Description

Strength through Unity and Inclusion

The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled legacy of achievement, education, and innovation as we work together to transform healthcare. We encourage all team members to actively participate in creating a culture that ensures fair access to opportunities, promotes inclusive practices, and supports the success of every individual.

At Mount Sinai, our leaders are committed to fostering a workplace where all employees feel valued, respected, and empowered to grow. We strive to create an environment where collaboration, fairness, and continuous learning drive positive change, improving the well‑being of our staff, patients, and organization. Our leaders are expected to challenge outdated practices, promote a culture of respect, and work toward meaningful improvements that enhance patient care and workplace experiences. We are dedicated to building a supportive and welcoming environment where everyone has the opportunity to thrive and advance professionally. Explore this opportunity and be part of the next chapter in our history.

About The Mount Sinai Health System

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high‑quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

Equal Opportunity Employer

The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.

Compensation

The Mount Sinai Health System (MSHS) provides salary ranges that comply with the New York City Law on Salary Transparency in Job Advertisements. The salary range for the role is $58661 - $98978.78 Annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range or contractual rate listed does not include bonuses/incentive, differential pay or other forms of compensation or benefits.