Associate Scientist, Immunology

Flagship Pioneering, Inc.; Cambridge (MA); On-site; USD 96,000 - 127,000; Full time

Job summary

Serif Biomedicines, a Flagship Pioneering portfolio company, is seeking an Associate Scientist of Immunology to join the therapeutic discovery team in Cambridge, MA. The role focuses on benchwork using in vitro and ex vivo approaches to advance Modified DNA therapies for autoimmune diseases and cancer immunotherapy.

You will design assays, perform tissue processing, and troubleshoot protocols under senior guidance while contributing to data presentation and collaboration across projects.

Qualifications

• BS or MS in biology, immunology, bioengineering or related discipline.
• 6+ years of relevant industry experience in immunology and/or immunotherapy.
• Strong experimental skills including tissue culture and flow cytometry.
• Experience with human and/or NHP T cells is preferred.

Responsibilities

• Independently design and execute in vitro assays to evaluate immune cell function, including multi-color flow cytometry and cytotoxicity assays.
• Conduct ex vivo analysis of immune cells through tissue processing and downstream assays.
• Develop, execute, and troubleshoot experimental protocols under guidance of senior team members and maintain accurate electronic lab notebook records.
• Analyze and communicate experimental data at team meetings.

Skills

Flow cytometry

T cell culture

Immunoassay development

Ex vivo analysis

Non-viral delivery

Education

BS or MS in biology/immunology/bioengineering or related field

Job description

Serif Biomedicines is a privately held, early-stage biotechnology company pioneering Modified DNA as a new class of medicines. Modified DNA brings together the best features of mRNA and gene therapy, while mitigating their limitations, by enabling medicines that are durable, redosable, programmable, and scalable. Serif was founded by Flagship Pioneering, an innovation enterprise that conceives, creates, resources, and grows first-in-category life sciences companies.

Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Generate Biomedicines (GENB), Seres Therapeutics (MCRB), Tessera Therapeutics, and Lila Sciences.

Position Summary:

We are seeking a highly motivated Associate Scientist of Immunology to join our therapeutic discovery team. The candidate will focus on hands‑on benchwork using in vitro and ex vivo experimental approaches. The candidate must be independent, goal oriented, technically competent and able to efficiently work across multiple projects. We are searching for enthusiastic, innovative, and highly motivated individuals, with scientific background in immunology, cancer immunotherapy, and/or autoimmune diseases, who are comfortable working in a fast‑paced entrepreneurial environment.

Key Responsibilities:

• Independently design and execute in vitro assays to evaluate immune cell function, including multi‑color flow cytometry, cytotoxicity assays and other functional readouts under the guidance of scientists
• Conduct ex vivo analysis of immune cells through tissue processing and downstream assays and analyses
• Develop, execute, and troubleshoot experimental protocols under the guidance of senior members on the team, and maintain accurate and timely electronic laboratory notebook records
• Analyze and communicate experimental data at team meetings

Qualifications:

• BS or MS degree in biology, immunology, bioengineering or related discipline with 6+ year of relevant industry experience in immunology and/or immunotherapy.
• Strong experimental skills, including tissue culture, primary immune cell culture, flow cytometry, immunoassay development, and ex vivo mouse model and NHP sample processing
• Experience with non‑viral delivery technologies and nucleic acid modalities is preferred
• Experience with primary human and/or NHP T cells is preferred
• Detail oriented, self‑motivated, and comfortable working with highly technical projects and personnel
• Highly adaptable and responsive to delivering challenging commitments

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

At Flagship, we recognize there is no perfect candidate. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies

Flagship Pioneering and its affiliated Flagship Lab companies (collectively, 'FSP') do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The salary range for this role is $96,000 - $126,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Serif Biomedicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Serif Biomedicines’s good faith estimate as of the date of publication and may be modified in the future.

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