Associate Scientist II, Research

Vaxcyte; San Carlos (CA); On-site; USD 108,000 - 120,000; Full time

Benefits offered by this job

Equity component

Comprehensive benefits

Job summary

Vaxcyte is seeking an energetic and talented individual to join the Research Department as a key support role. You will assist senior scientists with pre-formulation and formulation studies for novel vaccine candidates, stability studies to select optimum formulations for tech transfer, and process development to support multiple projects.

The role requires hands-on laboratory work, accurate ELN documentation, and close collaboration with Analytical and other teams.

Qualifications

• BA/BS in Pharmaceutical Sciences or related field with 2+ years of industrial experience; or MS with 1+ year industrial experience.
• Experience in preparation of buffers and lab reagents.
• Experience in basic biological characterization techniques (pH, Nanodrop, biochemical assays, particle size).
• Structured lab work, notebook upkeep, data generation and presentation.
• Excel for data entry/analysis; understanding of statistical analysis preferred.
• Attention to detail and pipetting skills.
• Ability to work collaboratively in cross-functional teams.
• Strong written and verbal communication skills.

Responsibilities

• Conduct pre-formulation and formulation studies, including bio-characterization and stability studies.
• Provide testing support (protein concentration, pH, visual assessments).
• Assist in developing analytical methods for biocharacterization (DSC, CD, SEC).
• Support process development for ongoing research projects.
• Maintain accurate experiment records in Vaxcyte's ELN system.
• Collaborate with Analytical and other Research teams within a cross-functional environment.
• Be scientifically proactive, agile in thought and execution.

Education

Bachelor's degree in Pharmaceutical Sciences / Organic Biochemistry / Chemical Biochemical Engineering / Biology

Master's degree in one of the listed disciplines

Tools

Excel

ELN system

Job description

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.

WHATwe do is every bit as important asHOWwe do it!Our work together is guided by four enduring core values:

*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.

*AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.

*LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.

*MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.

Summary:

Vaxcyte is looking for an energetic and talented individual to play a key supporting role in the Research Department.
The successful candidate will be proficient in basic laboratory techniques and be responsible for the support of the senior scientists in the execution of large and complex experimentation. These experiments will primarily take the form of pre-formulation and formulation studies for novel vaccine candidates, stability studies designed to select optimum formulation for tech transfer, process development studies to support projects within research department and troubleshooting studies to remove roadblocks for early-stage pipeline projects.

Essential Functions:

• Conducting and coordinating pre-formulation and formulation studies, including bio-characterization studies, excipient screening, short- and long-term stability studies.
• Responsible for testing support for within the team which includes running assays such as protein concentration, pH and visual assessments.
• Support senior scientists in developing analytical methods for biocharacterization of large molecules such as DSC, CD, SEC and other similar techniques.
• Support senior scientists in developing processes to support a wide range of ongoing research projects.
• Being scientifically accurate and keeping excellent written records of experiments undertaken using Vaxcyte’s ELN system.
• This position will report into the Formulation and Process line within the Research Department. Significant partnerships with the Analytical and other research teams will occur, thus ability to work within this collaborative environment is essential.
• This role will require the incumbent to be agile in both thought processes and practical execution. In addition, being scientifically pro-active within the small group will be encouraged.

Requirements:

• BA/BS in Pharmaceutical Sciences, Organic/Biochemistry, Chemical/Biochemical Engineering, Biology, or a related discipline, with a minimum of 2 years of industrial experience; or MS in one of these disciplines with a minimum of 1 year of industrial experience.
• Experience in preparation of buffers and lab reagents required.
• Experience in basic biological characterization techniques preferred, including pH, Nanodrop, biochemical assays and particle size determinations
• Highly efficient and structured work practices including practical laboratory work, notebook upkeep, data generation and presentation to research and wider teams.
• Experience with analytical software like Excel for data entry/maintenance and analysis. An understanding of analytical statistical analysis is also preferred.
• Attention to detail and excellent skills in pipetting and sample preparation
• Demonstrated ability to work collaboratively in a cross-functional team environment on multiple projects.
• Strong interpersonal skills, with excellent written and verbal communication skills

Reports to: Staff Scientist, Research

Work Arrangement (may be adjusted based on business needs, job responsibilities, or changes to company policy):

Onsite (minimum of 4 days per week onsite)

Compensation:

The compensation package will be competitive and includes comprehensive benefits and an equity component.

Salary Range: $108,000 - $120,000

We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.

Voluntary Self-Identification

For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.

As set forth in Vaxcyte’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.

If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:

A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.

A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.

An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.

An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.