Associate Scientist I/II, Discovery Neuroscience

BioSpace; Cambridge (MA); On-site; USD 90,000 - 130,000; Full time

Benefits offered by this job

Medical/dental/vision insurance

401(k) plan

Paid time off

Short-term incentive programs

Job summary

AbbVie is seeking a highly motivated cell biologist to join its Discovery Neuroscience group. The role supports early discovery for Parkinson's and related neurodegenerative diseases with in vitro data generation and model development.

You will work with scientists across discovery biology to advance programs, using neuronal cultures, iPSC-derived neurons, and recombinant cell lines, while ensuring data quality and compliance.

Qualifications

• Bachelors degree in Biology, Neuroscience, Pharmacology, Biochemistry, or related field.
• Hands-on experience with cellular biology techniques and data generation.
• Ability to work independently and in cross-functional teams.

Responsibilities

• Design, execute, and interpret cellular experiments to support discovery neuroscience programs.
• Collaborate with cross-functional project teams to support program objectives and data interpretation.
• Maintain and work with primary neuronal cultures, iPSC-derived neurons and glia, and other in vitro models.
• Support compound testing, genetic knockdown/KO and overexpression studies, assay development, and proof-of-concept studies.
• Contribute to assay optimization, troubleshooting, and new in vitro method implementation.
• Generate, organize, and analyze experimental data with accuracy and reproducibility.
• Maintain detailed and compliant experimental records and study documentation.

Skills

High-content imaging

Immunofluorescence

Cell viability assays

Reporter assays

ELISA

qPCR

In vitro neuronal models

Education

Bachelor's degree in Biology/Neuroscience/Pharmacology/Biochemistry

MS degree in related field

Job description

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.

Company Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube.

Job Description

We are seeking a highly motivated cell biologist to join our Discovery Neuroscience organization. This scientist will contribute to early discovery research efforts focused on identifying and advancing novel therapeutic approaches for Parkinsons Disease and related neurodegenerative diseases. This laboratory-based role will support in vitro data generation, cell culture-based model development, evaluation of small molecule and biologic therapeutics, and execution of proof-of-concept studies in a collaborative discovery environment. The successful candidate will work closely with scientists across discovery biology and translational functions to generate high-quality data that inform program decisions.

Key Responsibilities

• Design, execute, and interpret cellular experiments to support discovery neuroscience programs.
• Collaborate effectively with cross-functional project teams to support program objectives and data interpretation.
• Maintain and perform routine work with primary neuronal cultures, iPSC-derived neurons and glia, recombinant cell lines, and other neuroscience-relevant in vitro models.
• Support compound testing, genetic knockdown/KO and overexpression studies, assay development, and proof-of-concept studies through careful execution of experimental workflows.
• Contribute to assay optimization, troubleshooting, and implementation of new or modified in vitro methods.
• Generate, organize, and analyze experimental data with a high degree of accuracy and reproducibility.
• Maintain detailed and compliant experimental records, observations, and study documentation.
• Adhere to applicable safety, quality, and data integrity standards.

Required Qualifications

• Associate Scientist I: Bachelors degree in Biology, Neuroscience, Pharmacology, Biochemistry, or a related scientific discipline (no additional experience) in an academic, biotech, or pharmaceutical setting.
• Associate Scientist II: Bachelors degree with at least 3 years of experiencein Biology, Neuroscience, Pharmacology, Biochemistry, or a related scientific disciplineor MS (no additional experience)
• Hands-on experience with high-content imaging, immunofluorescence, cell viability and reporter assays, ELISA, qPCR, and/or related cellular biology techniques.
• Strong organizational skills, attention to detail, and commitment to high-quality data generation.
• Effective written and verbal communication skills.
• Ability to work independently and collaboratively in a fast-paced, team-oriented environment.

Preferred Qualifications

• Experience with primary neuronal culture, iPSC-derived neurons and glia, and immortalized neuronal and glial cell lines.
• Exposure to compound screening, assay development, troubleshooting, high-content image analysis, and mechanism of action studies in a discovery setting.
• Experience analyzing and presenting experimental data.
• Knowledge of neuroscience and/or neurodegenerative disease biology.
• Familiarity with statistical analysis or data visualization tools.

Core Competencies

• Scientific rigor and experimental discipline
• Strong attention to detail and follow-through
• Curiosity, initiative, and problem-solving mindset
• Collaboration and adaptability
• Commitment to data quality, reproducibility, and compliance

Additional Information

• The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at thetimeofthis posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographiclocation,andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.
• This job is eligible toparticipatein our short-term incentiveprograms.

Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.Theamountandavailabilityof anybonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company'ssoleandabsolutediscretion unless and until paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law.

Equal Opportunity

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html