Associate Scientist - Chemistry

City Therapeutics; Cambridge (MA); On-site; USD 70,000 - 90,000; Full time

Job summary

A leading biotechnology company in Cambridge, Massachusetts is seeking a dedicated Associate Scientist to join their Chemistry team. In this full-time onsite role, you will perform QC testing to support the development of RNA medicines and contribute to continuous method improvement. The ideal candidate holds a BS in Chemistry with 1-2 years of lab experience, and demonstrates strong skills in analytical testing and laboratory instrumentation.

Qualifications

• At least 1-2 years of chemistry lab experience in an industrial or academic setting.
• Knowledge of analytical chemistry and oligonucleotide chemistry.

Responsibilities

• Perform QC testing to support internal synthesis and activities in R&D.
• Demonstrate knowledge of analytical testing to support method implementation.
• Operate and troubleshoot laboratory instrumentation.

Skills

Analytical testing (U/HPLC, LC-MS, etc.)

Laboratory instrumentation maintenance

Communication skills

Education

BS in Chemistry or related field

Tools

Cary UV-Vis

Agilent LC-QTOF

Job description

We are seeking a dedicated and detail-oriented Associate Scientist to join our Chemistry team in developing next-generation RNA medicines. The ideal candidate will be highly motivated, passionate about early-discovery work, eager to learn, and capable of adapting flexibly to a dynamic work environment.

Please note this is a full-time onsite opportunity

Responsibilities

• Independently performs a variety of moderate to complex QC testing to support internal synthesis, biology, bioanalytical, and CMC activities in an R&D setting. Contributes to the expansion of QC capabilities by contributing to continuous method improvement and implementation of new analytical tests.
• Demonstrates knowledge of analytical testing (U/HPLC, LC-MS, endotoxin, spectroscopy, etc.) to support method implementation and routine testing.
• Operate, maintain, and troubleshoot laboratory instrumentation such as Cary UV-Vis, Endosafe nexgen-MCS, osmometer, pH meter, Agilent LC-QTOF, and other state-of-the-art laboratory equipment, ensuring their proper use and performance.
• Closely work with internal research departments to communicate timelines and facilitate QC requests.
• Track progress, generate status updates, organize experimental data, and present in both written and oral formats at cross-functional team meetings.
• Prepare SOPs and accurately record detailed experimental procedures and results in electronic lab notebooks. Peer review data related to chemistry testing.

Qualifications

• BS in Chemistry or a related field.
• At least 1-2 years of chemistry lab experience in an industrial or academic setting, preferably in RNA therapeutics.
• Knowledge of analytical chemistry and/or oligonucleotide chemistry, including purity analysis by LC-MS, analysis of impurities, and characterization of compounds by mass spectrometry etc.

City Therapeutics is accepting resumes/CVs from direct applicants only. Recruitment Agency inquiries or submissions will not be accepted at this time.

City Therapeutics is an Equal Opportunity and Affineative Action employer committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race;color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.